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Platform trials have gained a lot of attention recently as a possible remedy for time-consuming classical two-arm randomized controlled trials, especially in early phase drug development. This short article illustrates how to use the…

The R package optimParallel provides a parallel version of the gradient-based optimization methods of optim(). The main function of the package is optimParallel(), which has the same usage and output as optim(). Using optimParallel() can…

Computation · Statistics 2018-05-01 Florian Gerber , Reinhard Furrer

In this paper we propose a novel R package, called rsurv, developed for general survival data simulation purposes. The package is built under a new approach to simulate survival data that depends heavily on the use of dplyr verbs. The…

Computation · Statistics 2024-06-05 Fábio N. Demarqui

In this paper, we introduce a package for semi-supervised learning research in the R programming language called RSSL. We cover the purpose of the package, the methods it includes and comment on their use and implementation. We then show,…

Machine Learning · Statistics 2016-12-26 Jesse H. Krijthe

Many parallel and distributed computing research results are obtained in simulation, using simulators that mimic real-world executions on some target system. Each such simulator is configured by picking values for parameters that define the…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-07-03 Jesse McDonald , Maximilian Horzela , Frédéric Suter , Henri Casanova

The past decade has seen an increasing body of literature devoted to the estimation of causal effects in network-dependent data. However, the validity of many classical statistical methods in such data is often questioned. There is an…

Computation · Statistics 2017-05-31 Oleg Sofrygin , Romain Neugebauer , Mark J. van der Laan

The current landscape of scientific research is widely based on modeling and simulation, typically with complexity in the simulation's flow of execution and parameterization properties. Execution flows are not necessarily straightforward…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-07-26 Eduardo Ponce , Brittany Stephenson , Suzanne Lenhart , Judy Day , Gregory D. Peterson

We are living in the big data age: An ever increasing amount of data is being produced through data acquisition and computer simulations. While large scale analysis and simulations have received significant attention for cloud and…

Graphics · Computer Science 2019-02-26 Stefan Eilemann

Results of simulation studies evaluating the performance of statistical methods are often considered actionable and thus can have a major impact on the way empirical research is implemented. However, so far there is limited evidence about…

It is critical to accurately simulate data when employing Monte Carlo techniques and evaluating statistical methodology. Measurements are often correlated and high dimensional in this era of big data, such as data obtained in…

The capability of R to do symbolic mathematics is enhanced by the caracas package. This package uses the Python computer algebra library SymPy as a back-end but caracas is tightly integrated in the R environment. This enables the R user…

Applications · Statistics 2023-08-22 Mikkel Meyer Andersen , Søren Højsgaard

Background: Clinical prediction models are increasingly used to inform healthcare decisions, but determining the minimum sample size for their development remains a critical and unresolved challenge. Inadequate sample sizes can lead to…

Machine Learning · Computer Science 2026-03-02 Diana Shamsutdinova , Felix Zimmer , Oyebayo Ridwan Olaniran , Sarah Markham , Daniel Stahl , Gordon Forbes , Ewan Carr

We present `latentcor`, an R package for correlation estimation from data with mixed variable types. Mixed variables types, including continuous, binary, ordinal, zero-inflated, or truncated data are routinely collected in many areas of…

Computation · Statistics 2022-04-22 Mingze Huang , Christian L. Müller , Irina Gaynanova

Simulation studies allow us to explore the properties of statistical methods. They provide a powerful tool with a multiplicity of aims; among others: evaluating and comparing new or existing statistical methods, assessing violations of…

Applications · Statistics 2020-05-05 Alessandro Gasparini , Tim P. Morris , Michael J. Crowther

Evaluating forecasts is essential to understand and improve forecasting and make forecasts useful to decision makers. A variety of R packages provide a broad variety of scoring rules, visualisations and diagnostic tools. One particular…

Methodology · Statistics 2024-11-04 Nikos I. Bosse , Hugo Gruson , Anne Cori , Edwin van Leeuwen , Sebastian Funk , Sam Abbott

Mathematica is a powerful application package for doing mathematics and is used almost in all branches of science. It has widespread applications ranging from quantum computation, statistical analysis, number theory, zoology, astronomy, and…

Mathematical Software · Computer Science 2015-10-29 Santanu K. Maiti

The R package micompr implements a procedure for assessing if two or more multivariate samples are drawn from the same distribution. The procedure uses principal component analysis to convert multivariate observations into a set of linearly…

Mathematical Software · Computer Science 2021-05-11 Nuno Fachada , João Rodrigues , Vitor V. Lopes , Rui C. Martins , Agostinho C. Rosa

Here practical aspects of conducting research via computer simulations are discussed. The following issues are addressed: software engineering, object-oriented software development, programming style, macros, make files, scripts, libraries,…

Condensed Matter · Physics 2009-02-02 Alexander K. Hartmann , Heiko Rieger

With the advent of multi-core processors and their fast expansion, it is quite clear that {\em parallel computing} is now a genuine requirement in Computer Science and Engineering (and related) curriculum. In addition to the pervasiveness…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-02-13 Claude Tadonki

Package spar for R builds ensembles of predictive generalized linear models with high-dimensional predictors. It employs an algorithm utilizing variable screening and random projection tools to efficiently handle the computational…

Computation · Statistics 2024-11-28 Roman Parzer , Laura Vana-Gür , Peter Filzmoser