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Ion Mobility Spectrometry (IMS) is a well-known, sensitive and rapid technique to detect dangerous organic compounds. We propose a system in which a crown type discharge generates a ionic flow that is swept towards an array of collectors by…
We have operated a Medipix2 CMOS readout chip, with amplifying, shaping and charge discriminating front-end electronics integrated on the pixel-level, as a highly segmented direct charge collecting anode in a three-stage gas electron…
In this projecting work we propose a mass spectrometric patch-clamp equipment with the capillary performing both a local potential registration at the cell membrane and the analyte suction simultaneously. This paper provides a current…
Multispectral object detection aims to leverage complementary information from visible (RGB) and infrared (IR) modalities to enable robust performance under diverse environmental conditions. Our key insight, derived from wavelet analysis…
(abr.) We consider the potential of future microwave spectrometers akin to PIXIE in light of the sky-averaged global signal expected from the total intensity of extragalactic carbon monoxide (CO) and ionized carbon ([CII]) line emission. We…
Owing to its capacity for unique (bio)-chemical specificity, microscopy withmid-IR illumination holds tremendous promise for a wide range of biomedical and industrial applications. The primary limitation, however, remains detection; with…
In our article we report first quantitative measurements of imaging performance for the current generation of hybrid pixel detector, Medipix3, as direct electron detector. Utilising beam energies of 60 & 80 keV, measurements of modulation…
Analyzing microscopy images to extract biological object properties (e.g., their morphological organization, temporal dynamics, and population density) is fundamental to various biomedical research. Yet conducting this manually is costly…
Lensless on-chip microscopy has shown great potential for biomedical imaging due to its large-area and high-throughput imaging capabilities. By combining the pixel super-resolution (PSR) technique, it can improve the resolution beyond the…
Our work aims at using quantitative imaging tools to complement the limitation of noise encountered by high resolution fluorescence microscopy methods. Several cycles of fluorophore activation, imaging and deactivation produce a sequence of…
Ghost imaging is an unconventional imaging technique that generates high resolution images by correlating the intensity of two light beams, neither of which independently contains useful information about the shape of the object. Ghost…
Millimetre-wave observations represent an important tool for Cosmology studies. The Line Intensity Mapping (LIM) technique has been proposed to map in three dimensions the specific intensity due to line (e.g. [CII], CO) emission, for…
Structured illumination microscopy (SIM) is an important super-resolution based microscopy technique that breaks the diffraction limit and enhances optical microscopy systems. With the development of biology and medical engineering, there…
The Chinese Space Station Survey Telescope (CSST) is a next-generation Stage-IV facility renowned for its wide field of view, high image quality, and multi-band observational capabilities. Among the five instruments onboard the CSST, the…
Chopping observations with a tip-tilt secondary mirror have conventionally been used in ground-based mid-infrared observations. However, it is not practical for next generation large telescopes to have a large tip-tilt mirror that moves at…
Charged particle therapy (CPT) is an advanced modality of radiation therapy which has grown rapidly worldwide, driven by recent developments in technology and methods of delivery. To ensure safe and high quality treatments, various…
The upgrade of the China Spallation Neutron Source (CSNS-II) will raise the proton beam power to 500 kW. Consequently, the existing Timepix3-based detector systems, limited to a count rate of 80 Mhits/s, will encounter severe saturation…
We demonstrate an approach to two-dimensional electronic spectroscopy (2DES) that combines the benefits of shot-to-shot detection at high-repetition rates with the simplicity of a broadband white light continuum input and conventional…
Confocal laser-scanning microscopy (CLSM) is one of the most popular optical architectures for fluorescence imaging. In CLSM, a focused laser beam excites the fluorescence emission from a specific specimen position. Some actuators scan the…
Interferometric scattering microscopy has been a very promising technology for highly sensitive label-free imaging of a broad spectrum of biological nanoparticles from proteins to viruses in a high-throughput manner. Although it can reveal…