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In [Math. Comput. Sci. 12 (2018), no. 2, 111--127], a delayed model describing the dynamics of the Human Immunodeficiency Virus (HIV) with Cytotoxic T Lymphocytes (CTL) immune response is investigated by Allali, Harroudi and Torres. Here,…

Dynamical Systems · Mathematics 2022-10-03 Sandra Vaz , Delfim F. M. Torres

Malaria is one of the deadliest infectious diseases globally, causing hundreds of thousands of deaths each year. It disproportionately affects young children, with two-thirds of fatalities occurring in under-fives. Individuals acquire…

Populations and Evolution · Quantitative Biology 2023-06-07 Zhuolin Qu , Denis Patterson , Lauren Childs , Christina Edholm , Joan Ponce , Olivia Prosper , Lihong Zhao

We consider a branching model for a population of dividing cells infected by parasites. Each cell receives parasites by inheritance from its mother cell and independent contamination from outside the population. Parasites multiply randomly…

Probability · Mathematics 2009-08-05 Vincent Bansaye

This paper proposes a novel discrete-time multi-virus SIR (susceptible-infected-recovered) model that captures the spread of competing SIR epidemics over a population network. First, we provide a sufficient condition for the infection level…

Systems and Control · Electrical Eng. & Systems 2022-04-05 Ciyuan Zhang , Sebin Gracy , Tamer Basar , Philip E. Pare

This paper investigates the effect of drug treatment on the standard within-host HIV model, assuming that therapy occurs periodically. It is shown that eradication is possible under these periodic regimes, and we quantitatively characterize…

Other Quantitative Biology · Quantitative Biology 2008-01-30 Patrick De Leenheer

We discuss the criticality in the stochastic SIR model for infectious diseases. We adopt the path-integral formalism for the propagation of infections among susceptible, infectious, and removed individuals, and perform the perturbative and…

Populations and Evolution · Quantitative Biology 2022-02-14 Shigehiro Yasui , Yutaka Hatakeyama , Yoshiyasu Okuhara

During an infection, HIV experiences strong selection by immune system T cells. Recent experimental work has shown that MHC escape mutations form an important pathway for HIV to avoid such selection. In this paper, we study a model of MHC…

Probability · Mathematics 2009-09-02 Sivan Leviyang

A simple deterministic model is proposed to represent the basic aspects concerning the effects of different antiretroviral treatment schedules on HIV incidence and prevalence of affected populations. The model mimics current treatment…

Populations and Evolution · Quantitative Biology 2009-09-29 L. F. Lopez , F. A. B. Coutinho , M. N. Burattini , E. Massad

In this paper, we first propose a diffusive pathogen infection model with general incidence rate which incorporates cell-to-cell transmission. By applying the theory of monotone dynamical systems, we prove that the model admits the global…

Analysis of PDEs · Mathematics 2026-02-24 Shohel Ahmed

HIV is a deadly virus transmitted either through having of unprotected sex, mother to child transmission, sharing of unsterilized objects that is capable of making cut or wounds on the body, through blood or bodily fluid transmission. AIDS…

Populations and Evolution · Quantitative Biology 2016-09-19 M. O. Oladejo , Ali Onuche John

HIV virus replication is a time-related process that includes several stages. Focusing on the core steps, RNA polymerase II transcripts in an early stage pre-mRNA containing regulator proteins (i.e nef,tat,rev,vif,vpr,vpu), which are…

Genomics · Quantitative Biology 2020-04-03 Miguel Ramos Pascual

In this work, we use a new approach to study the spread of an infectious disease. Indeed, we study a SIR epidemic model with variable infectivity, where the individuals are distributed over a compact subset $D$ of $\R^d$. We define…

Probability · Mathematics 2025-11-18 Armand Kanga , Etienne Pardoux

We develop a stochastic framework for viral population dynamics at the cellular level that explicitly incorporates the replication cycle with random stage durations. The model is formulated as a structured birth-death process coupled with a…

Populations and Evolution · Quantitative Biology 2026-05-13 Seong Jun Park

The SIR model with spatially inhomogeneous infection rate is studied with numerical simulations in one, two, and three dimensions, considering the case that the infection spreads inhomogeneously in densely populated regions or hot spots. We…

Medical Physics · Physics 2020-12-25 Hidetsugu Sakaguchi , Yuta Nakao

It is the main purpose of this paper to introduce a graph-valued stochastic process in order to model the spread of a communicable infectious disease. The major novelty of the SIR model we promote lies in the fact that the social network on…

Applications · Statistics 2014-02-06 Charanpal Dhanjal , Stéphan Clémençon

In this paper we consider epidemic models of directly transmissible SIR (susceptible $\to$ infective $\to$ recovered) and SEIR (with an additional latent class) infections in fully-susceptible populations with a social structure, consisting…

Populations and Evolution · Quantitative Biology 2015-12-11 Frank Ball , Lorenzo Pellis , Pieter Trapman

We consider an epidemic model of SIR type set on a homogeneous tree and investigate the spreading properties of the epidemic as a function of the degree of the tree, the intrinsic basic reproduction number and the strength of the…

Analysis of PDEs · Mathematics 2021-06-09 Christophe Besse , Grégory Faye

In this article, we discuss an age-structured SIR model in which disease not only spread through direct person to person contacts for e.g. infection due to surface contamination but it can also spread through indirect contacts. It is…

Populations and Evolution · Quantitative Biology 2020-07-24 Manoj Kumar , Syed Abbas

The time-dependent reproduction number Rt can be used to track pathogen transmission and to assess the efficacy of interventions. This quantity can be estimated by fitting renewal equation models to time series of infectious disease case…

Populations and Evolution · Quantitative Biology 2025-01-30 Ioana Bouros , Robin Thompson , David Gavaghan , Ben Lambert

The Susceptible-Infected-Recovered (SIR) model has successfully mimicked the propagation of such airborne diseases as influenza A (H1N1). Although the SIR model has recently been studied in a multilayer networks configuration, in almost all…

Physics and Society · Physics 2015-07-16 L. G. Alvarez Zuzek , H. E. Stanley , L. A. Braunstein