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Nanoparticles introduced in living cells are capable of strongly promoting the aggregation of peptides and proteins. We use here molecular dynamics simulations to characterise in detail the process by which nanoparticle surfaces catalyse…

Biomolecules · Quantitative Biology 2010-06-08 Stefan Auer , Antonio Trovato , Michele Vendruscolo

We examine the structure of compact metal nanoparticles (NPs) forming polyhedral sections of face centered (fcc) and body centered (bcc) cubic lattices, which are confined by facets characterized by highly dense {100}, {110}, and {111}…

Atomic and Molecular Clusters · Physics 2022-03-21 Klaus E. Hermann

Graph embeddings have become a key and widely used technique within the field of graph mining, proving to be successful across a broad range of domains including social, citation, transportation and biological. Graph embedding techniques…

Machine Learning · Computer Science 2018-06-21 Stephen Bonner , Ibad Kureshi , John Brennan , Georgios Theodoropoulos , Andrew Stephen McGough , Boguslaw Obara

In contrast to extensively studied defects in traditional materials, we report here for the first time a systematic investigation of the formation mechanism of intrinsic defects in self-assembled peptide nanostructures. The Monte Carlo…

Soft Condensed Matter · Physics 2015-11-11 Li Deng , Yurong Zhao , Hai Xu , Yanting Wang

Repetitive DNA (repeats) poses significant challenges for accurate and efficient genome assembly and sequence alignment. This is particularly true for metagenomic data, where genome dynamics such as horizontal gene transfer, gene…

Machine Learning · Computer Science 2024-02-15 Ali Azizpour , Advait Balaji , Todd J. Treangen , Santiago Segarra

Cellular functions are established through biological evolution, but are constrained by the laws of physics. For instance, the physics of protein folding limits the lengths of cellular polypeptide chains. Consequently, many cellular…

Biological Physics · Physics 2019-07-09 Pablo Sartori , Stanislas Leibler

The discovery and analysis of network patterns are central to the scientific enterprise. In the present work, we developed and evaluated a new approach that learns the building blocks of graphs that can be used to understand and generate…

Social and Information Networks · Computer Science 2018-02-26 Salvador Aguinaga , David Chiang , Tim Weninger

Graphs face challenges when dealing with massive datasets. They are essential tools for modeling interconnected data and often become computationally expensive. Graph embedding techniques, on the other hand, provide an efficient approach.…

Databases · Computer Science 2024-12-16 Plácido A Souza Neto

For graph classification tasks, many traditional kernel methods focus on measuring the similarity between graphs. These methods have achieved great success on resolving graph isomorphism problems. However, in some classification problems,…

Machine Learning · Computer Science 2021-02-18 Jianming Huang , Hiroyuki Kasai

Graph embedding techniques allow to learn high-quality feature vectors from graph structures and are useful in a variety of tasks, from node classification to clustering. Existing approaches have only focused on learning feature vectors for…

Artificial Intelligence · Computer Science 2019-05-29 Valeria Fionda , Giuseppe Pirró

Deciding whether a graph can be embedded in a grid using only unit-length edges is NP-complete, even when restricted to binary trees. However, it is not difficult to devise a number of graph classes for which the problem is polynomial, even…

Data Structures and Algorithms · Computer Science 2012-04-13 Vinícius G. P. de Sá , Guilherme D. da Fonseca , Raphael Machado , Celina M. H. de Figueiredo

Many innovative applications require establishing correspondences among 3D geometric objects. However, the countless possible deformations of smooth surfaces make shape matching a challenging task. Finding an embedding to represent the…

Computer Vision and Pattern Recognition · Computer Science 2022-06-09 Riccardo Marin , Souhaib Attaiki , Simone Melzi , Emanuele Rodolà , Maks Ovsjanikov

We numerically study a simple fluid composed of particles having a hard-core repulsion, complemented by two short-ranged attractive (sticky) spots at the particle poles, which provides a simple model for equilibrium polymerization of linear…

Soft Condensed Matter · Physics 2009-11-13 F. Sciortino , E. Bianchi , J. F. Douglas , P. Tartaglia

The structure of membrane-active peptides and their interaction with lipid bilayers can be studied in oriented lipid membranes deposited on solid substrates. Such systems are desirable for a number of surface-sensitive techniques. Here we…

Soft Condensed Matter · Physics 2015-04-10 Chenghao Li , Doru Constantin , Tim Salditt

Entropy alone can self-assemble hard particles into colloidal crystals of remarkable complexity whose structures are the same as atomic and molecular crystals, but with larger lattice spacings. Although particle-based molecular simulation…

Soft Condensed Matter · Physics 2021-07-06 Thi Vo , Sharon C. Glotzer

Graphene-based nanostructured systems and van-der-Waals heterostructures comprise a material class of growing technological and scientific importance. Joining materials with vastly different properties, polymer-graphene heterosystems…

Soft Condensed Matter · Physics 2020-08-26 Max Gulde , Anastassia N. Rissanou , Vagelis Harmandaris , Marcus Müller , Sascha Schäfer , Claus Ropers

The characterization of protein-nanoparticle assemblies in solution remains a challenge. We demonstrate a technique based on a graphene microelectrode for structural-functional analysis of model systems composed of nanoparticles enclosed in…

Polyhedra and their arrangements have intrigued humankind since the ancient Greeks and are today important motifs in condensed matter, with application to many classes of liquids and solids. Yet, little is known about the thermodynamically…

Soft Condensed Matter · Physics 2012-01-25 Pablo F. Damasceno , Michael Engel , Sharon C. Glotzer

We report on self-assembly, clustering, and conformational phases of peptides on inorganic semiconductor surfaces. The peptide-covered surface fraction can differ by a factor of 25, depending mainly on surface and peptide polarity. Low…

Soft Condensed Matter · Physics 2009-11-13 Karsten Goede , Michael Bachmann , Wolfhard Janke , Marius Grundmann

Cyclodextrins (CD) are a family of oligosaccharides with a toroid shape, which exhibit a remarkable ability to include guest molecules in their internal cavity providing a hydrophobic environment for poorly soluble molecules. Recently new…

Soft Condensed Matter · Physics 2018-10-02 Florent Carn , Sophie Nowak , Ismail Chaab , Raul Diaz-Salmeron , Madeleine Djabourov , Kawthar Bouchemal