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Developing materials that can withstand the intense environments of nuclear fusion reactors is critical in developing long-term commercial viability for energy production. Tungsten is the primary candidate as a plasma facing material due to…

Materials Science · Physics 2023-12-11 Jarod Worden , Celine Hin

Segmentation of organs or lesions from medical images plays an essential role in many clinical applications such as diagnosis and treatment planning. Though Convolutional Neural Networks (CNN) have achieved the state-of-the-art performance…

Computer Vision and Pattern Recognition · Computer Science 2021-05-27 Xiangde Luo , Guotai Wang , Tao Song , Jingyang Zhang , Michael Aertsen , Jan Deprest , Sebastien Ourselin , Tom Vercauteren , Shaoting Zhang

A sensation of fullness in the bladder is a regular experience, yet the mechanisms that act to generate this sensation remain poorly understood. This is an important issue because of the clinical problems that can result when this system…

The mechanical properties of biological materials are spatially heterogeneous. Typical tissues are made up of a spanning fibrous extracellular matrix in which various inclusions, such as living cells, are embedded. While the influence of…

Soft Condensed Matter · Physics 2025-09-04 Jordan L. Shivers , Jingchen Feng , Fred C. MacKintosh

Diffusion-based and neural communication are two interesting domains in molecular communication. Both of them have distinct advantages and are exploited separately in many works. However, in some cases, neural and diffusion-based ways have…

Emerging Technologies · Computer Science 2015-07-07 Peng He , Yuming Mao , Qiang Liu , Kun Yang

Molecular simulations and biophysical experiments can be used to provide independent and complementary insights into the molecular origin of biological processes. A particularly useful strategy is to use molecular simulations as a modelling…

Chemical Physics · Physics 2019-12-10 Simone Orioli , Andreas Haahr Larsen , Sandro Bottaro , Kresten Lindorff-Larsen

Artificial neural networks took a lot of inspiration from their biological counterparts in becoming our best machine perceptual systems. This work summarizes some of that history and incorporates modern theoretical neuroscience into…

Neural and Evolutionary Computing · Computer Science 2022-09-12 Robert Bain

Living cells respond to mechanical changes in the matrix surrounding them by applying contractile forces that are in turn transmitted to distant cells. We calculate the mechanical work that each cell performs in order to deform the matrix,…

Soft Condensed Matter · Physics 2021-08-17 Chaviva Sirote , Yair Shokef

This paper presents the principal challenges and opportunities associated with computational biomechanics research. The underlying cognitive control involved in the process of human motion is inherently complex, dynamic, multidimensional,…

Traditional mathematical approaches to studying analytically the dynamics of neural networks rely on the mean-field approximation, which is rigorously applicable only to networks of infinite size. However, all existing real biological…

Neurons and Cognition · Quantitative Biology 2019-04-30 Diego Fasoli , Stefano Panzeri

Neuromorphic computing uses brain-inspired principles to design circuits that can perform computational tasks with superior power efficiency to conventional computers. Approaches that use traditional electronic devices to create artificial…

Applied Physics · Physics 2020-07-14 J. Grollier , D. Querlioz , K. Y. Camsari , K. Everschor-Sitte , S. Fukami , M. D. Stiles

We analytically study membrane mediated interactions between inclusions embedded in a tubular membrane. We model inclusions as constraints coupled to the curvature tensor of the membrane tube. First, as special test cases, we analyze the…

Biological Physics · Physics 2016-09-28 Afshin Vahid , Timon Idema

The structural characterization of microgels at interfaces is fundamental to understand both their 2D phase behavior and their role as stabilizers that enable emulsions to be broken on demand. However, this characterization is usually…

Individual Neurons in the nervous systems exploit various dynamics. To capture these dynamics for single neurons, we tune the parameters of an electrophysiological model of nerve cells, to fit experimental data obtained by calcium imaging.…

Quantitative Methods · Quantitative Biology 2017-11-07 Magdalena Fuchs , Manuel Zimmer , Radu Grosu , Ramin M. Hasani

Adhesion between two bodies is a key parameter in wear processes. At the macroscale, strong adhesive bonds are known to lead to high wear rates, as observed in clean metal-on-metal contact. Reducing the strength of the interfacial adhesion…

Soft Condensed Matter · Physics 2020-10-14 Enrico Milanese , Tobias Brink , Ramin Aghababaei , Jean-François Molinari

By leveraging their high mobility and small size, insects have been combined with microcontrollers to build up cyborg insects for various practical applications. Unfortunately, all current cyborg insects rely on implanted electrodes to…

Robotics · Computer Science 2023-03-21 Qifeng Lin , Rui Li , Feilong Zhang , Kai Kazuki , Ong Zong Chen , Xiaodong Chen , Hirotaka Sato

Manufacturing of microstructures using a microfluidic device is a largely empirical effort due to the multi-physical nature of the fabrication process. As such, models are desired that will predict microstructure performance characteristics…

Computational Engineering, Finance, and Science · Computer Science 2024-03-05 Nicholus R. Clinkinbeard , Reza Montazami , Nicole N. Hashemi

Transcranial ultrasonic stimulation (TUS) is rapidly gaining traction for non-invasive human neuromodulation, with a pressing need to establish protocols that maximise neuromodulatory efficacy. In this review, we aggregate and examine…

Biological Physics · Physics 2024-07-04 Tulika Nandi , Benjamin R. Kop , Kim Butts Pauly , Charlotte J. Stagg , Lennart Verhagen

In tissue engineering, we seek to address comprehensive tissue repair and regeneration needs. Aligned nanofibers have emerged as powerful and versatile tools, attributable to their structural and biochemical congruence with the natural…

Medical Physics · Physics 2024-08-16 Gayatri Patel , Louis-S. Bouchard

Deep learning techniques have successfully been employed in numerous computer vision tasks including image segmentation. The techniques have also been applied to medical image segmentation, one of the most critical tasks in computer-aided…

Computer Vision and Pattern Recognition · Computer Science 2020-06-30 Titinunt Kitrungrotsakul , Iwamoto Yutaro , Lanfen Lin , Ruofeng Tong , Jingsong Li , Yen-Wei Chen