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Modern high-dimensional point process data, especially those from neuroscience experiments, often involve observations from multiple conditions and/or experiments. Networks of interactions corresponding to these conditions are expected to…

Methodology · Statistics 2021-09-27 Xu Wang , Ali Shojaie

Primary health care frequently relies on low-cost imaging devices, which are commonly used for screening purposes. To ensure accurate diagnosis, these systems depend on advanced reconstruction algorithms designed to approximate the…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Thomas Pinetz , Veit Hucke , Hrvoje Bogunovic

With the advent of high-throughput wet lab technologies the amount of protein interaction data available publicly has increased substantially, in turn spurring a plethora of computational methods for in silico knowledge discovery from this…

Molecular Networks · Quantitative Biology 2015-05-06 Sriganesh Srihari , Hon Wai Leong

The structure of the supply chain network has important implications for modelling economic systems, from growth trajectories to responses to shocks or natural disasters. However, reconstructing firm-to-firm networks from available…

Physics and Society · Physics 2024-12-23 Leonardo Niccolò Ialongo , Sylvain Bangma , Fabian Jansen , Diego Garlaschelli

Background. Human aging is linked to many prevalent diseases. The aging process is highly influenced by genetic factors. Hence, it is important to identify human aging-related genes. We focus on supervised prediction of such genes. Gene…

Molecular Networks · Quantitative Biology 2020-04-28 Qi Li , Tijana Milenković

Reconstructing the equation of motion and thus the network topology of a system from time series is a very important problem. Although many powerful methods have been developed, it remains a great challenge to deal with systems in high…

Adaptation and Self-Organizing Systems · Physics 2023-08-16 Zishuo Yan , Lili Gui , Kun Xu , Yueheng Lan

With the advent of high-throughput profiling methods, interest in reverse engineering the structure and dynamics of biochemical networks is high. Recently an algorithm for reverse engineering of biochemical networks was developed by…

Quantitative Methods · Quantitative Biology 2010-01-18 Edgar Delgado-Eckert

In the postgenome era many efforts have been dedicated to systematically elucidate the complex web of interacting genes and proteins. These efforts include experimental and computational methods. Microarray technology offers an opportunity…

Molecular Networks · Quantitative Biology 2009-08-04 L. Diambra

In machine learning, graph embedding algorithms seek low-dimensional representations of the input network data, thereby allowing for downstream tasks on compressed encodings. Recently, within the framework of network renormalization,…

Physics and Society · Physics 2025-08-29 Riccardo Milocco , Fabian Jansen , Diego Garlaschelli

Samples from intimate (non-linear) mixtures are generally modeled as being drawn from a smooth manifold. Scenarios where the data contains multiple intimate mixtures with some constituent materials in common can be thought of as manifolds…

Computer Vision and Pattern Recognition · Computer Science 2017-08-15 Arun M. Saranathan , Mario Parente

We present a novel framework for understanding node target search in systems organized as hierarchical networks-within-networks. Our work generalizes traditional search models on complex networks, where the mean-first passage time is…

Biological Physics · Physics 2024-11-06 Lucas Hedström , Seong-Gyu Yang , Ludvig Lizana

Network reconstruction of dynamical continuous-time (CT) systems is motivated by applications in many fields. Due to experimental limitations, especially in biology, data could be sampled at low frequencies, leading to significant…

Systems and Control · Computer Science 2018-10-30 Zuogon Yue , Johan Thunberg , Lennart Ljung , Ye Yuan , Jorge Goncalves

Aligning protein interaction networks (PPI) of two or more organisms consists of finding a mapping of the nodes (proteins) of the networks that captures important structural and functional associations (similarity). It is a well studied but…

Molecular Networks · Quantitative Biology 2020-10-12 Concettina Guerra , Pietro Hiram Guzzi

Here we address the challenge of profiling causal properties and tracking the transformation of chemical compounds from an algorithmic perspective. We explore the potential of applying a computational interventional calculus based on the…

Molecular Networks · Quantitative Biology 2018-03-20 Hector Zenil , Narsis A. Kiani , Ming-Mei Shang , Jesper Tegnér

Protein-protein interaction (PPI) networks, providing a comprehensive landscape of protein interacting patterns, enable us to explore biological processes and cellular components at multiple resolutions. For a biological process, a number…

Molecular Networks · Quantitative Biology 2016-04-13 Xiuli Ma , Guangyu Zhou , Jingjing Wang , Jian Peng , Jiawei Han

In this paper, we explore a novel model reusing task tailored for graph neural networks (GNNs), termed as "deep graph reprogramming". We strive to reprogram a pre-trained GNN, without amending raw node features nor model parameters, to…

Computer Vision and Pattern Recognition · Computer Science 2023-05-01 Yongcheng Jing , Chongbin Yuan , Li Ju , Yiding Yang , Xinchao Wang , Dacheng Tao

One of the most important problems of data processing in high energy and nuclear physics is the event reconstruction. Its main part is the track reconstruction procedure which consists in looking for all tracks that elementary particles…

Machine Learning · Computer Science 2019-02-20 Dmitriy Baranov , Gennady Ososkov , Pavel Goncharov , Andrei Tsytrinov

This research is to search for alternatives to the resolution of complex medical diagnosis where human knowledge should be apprehended in a general fashion. Successful application examples show that human diagnostic capabilities are…

Neural and Evolutionary Computing · Computer Science 2010-09-28 Abu Bakar Siddiquee , Md. Ehsanul Hoque Mazumder , S. M. Kamruzzaman

Deep learning models have proven to be exceptionally useful in performing many machine learning tasks. However, for each new dataset, choosing an effective size and structure of the model can be a time-consuming process of trial and error.…

Machine Learning · Computer Science 2019-08-08 Roozbeh Yousefzadeh , Dianne P O'Leary

We report the possibility of using a simple neural network for effortless restoration of low-light images inspired by the retina model, which mimics the neurophysiological principles and dynamics of various types of optical neurons. The…

Image and Video Processing · Electrical Eng. & Systems 2022-10-06 Yurui Ming , Yuanyuan Liang