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This paper studies clustering of data sequences using the k-medoids algorithm. All the data sequences are assumed to be generated from \emph{unknown} continuous distributions, which form clusters with each cluster containing a composite set…

Machine Learning · Computer Science 2019-03-27 Tiexing Wang , Qunwei Li , Donald J. Bucci , Yingbin Liang , Biao Chen , Pramod K. Varshney

As single-cell gene expression data analysis continues to grow, the need for reliable clustering methods has become increasingly important. The prevalence of heuristic means for method choice could lead to inaccurate reports if…

Quantitative Methods · Quantitative Biology 2026-05-19 Owen Visser , Somnath Datta

To identify novel dynamic patterns of gene expression, we develop a statistical method to cluster noisy measurements of gene expression collected from multiple replicates at multiple time points, with an unknown number of clusters. We…

Applications · Statistics 2013-12-02 Audrey Qiuyan Fu , Steven Russell , Sarah J. Bray , Simon Tavaré

Image clustering is a particularly challenging computer vision task, which aims to generate annotations without human supervision. Recent advances focus on the use of self-supervised learning strategies in image clustering, by first…

Computer Vision and Pattern Recognition · Computer Science 2024-09-30 Foivos Ntelemis , Yaochu Jin , Spencer A. Thomas

Next-generation sequencing technologies provide a revolutionary tool for generating gene expression data. Starting with a fixed RNA sample, they construct a library of millions of differentially abundant short sequence tags or "reads",…

Quantitative Methods · Quantitative Biology 2014-05-13 Dimitrios V. Vavoulis , Julian Gough

We propose a modification of linear discriminant analysis, referred to as compressive regularized discriminant analysis (CRDA), for analysis of high-dimensional datasets. CRDA is specially designed for feature elimination purpose and can be…

Methodology · Statistics 2018-04-12 Muhammad Naveed Tabassum , Esa Ollila

Subgroup identification (clustering) is an important problem in biomedical research. Gene expression profiles are commonly utilized to define subgroups. Longitudinal gene expression profiles might provide additional information on disease…

Methodology · Statistics 2016-09-27 Jiehuan Sun , Jose D. Herazo-Maya , Naftali Kaminski , Hongyu Zhao , Joshua L. Warren

The Positron Emission Tomography (PET) scan image requires expertise in the segmentation where clustering algorithm plays an important role in the automation process. The algorithm optimization is concluded based on the performance, quality…

Computer Vision and Pattern Recognition · Computer Science 2013-03-01 A. Meena , K. Raja

Accurate information about protein content in the organism is instrumental for a better understanding of human biology and disease mechanisms. While the presence of certain types of proteins can be life-threatening, the abundance of others…

Quantitative Methods · Quantitative Biology 2022-01-19 Dmytro Fishman

Several studies have investigated the scaling behavior in naturally occurring biological and physical processes using techniques such as detrended fluctuation analysis (DFA). Data acquisition is an inherent part of these studies and maps…

Statistical Mechanics · Physics 2007-05-23 Radhakrishnan Nagarajan

Motivation:Microarray experiments result in large scale data sets that require extensive mining and refining to extract useful information. We demonstrate the usefulness of (nonmetric) multidimensional scaling (MDS) method in analyzing a…

Genomics · Quantitative Biology 2009-09-29 Y. -h. Taguchi , Y. Oono

With rapidly increasing data, clustering algorithms are important tools for data analytics in modern research. They have been successfully applied to a wide range of domains; for instance, bioinformatics, speech recognition, and financial…

Data Structures and Algorithms · Computer Science 2015-12-01 Ka-Chun Wong

Clustering is a separation of data into groups of similar objects. Every group called cluster consists of objects that are similar to one another and dissimilar to objects of other groups. In this paper, the K-Means algorithm is implemented…

Machine Learning · Computer Science 2013-04-03 P. Ashok , G. M Kadhar Nawaz , E. Elayaraja , V. Vadivel

This paper presents an inverted-file k-means clustering algorithm (IVF) suitable for a large-scale sparse data set with potentially numerous classes. Given such a data set, IVF efficiently works at high-speed and with low memory…

Machine Learning · Statistics 2020-02-24 Kazuo Aoyama , Kazumi Saito , Tetsuo Ikeda

Clustering of time series based on their underlying dynamics is keeping attracting researchers due to its impacts on assisting complex system modelling. Most current time series clustering methods handle only scalar time series, treat them…

Machine Learning · Statistics 2025-05-21 Zuogong Yue , Xinyi Wang , Victor Solo

In this work, we present an approach for evaluating segmentation strategies and solving the biological problem of creating robust interpretable maps of biological data by employing wards agglomerative hierarchical clustering applied to…

Quantitative Methods · Quantitative Biology 2024-02-13 Richard Tjörnhammar

The identification of disease-gene associations is instrumental in understanding the mechanisms of diseases and developing novel treatments. Besides identifying genes from RNA-Seq datasets, it is often necessary to identify gene clusters…

Genomics · Quantitative Biology 2025-11-14 Jake R. Patock , Rinki Ratnapriya , Arko Barman

In cluster analysis, a common first step is to scale the data aiming to better partition them into clusters. Even though many different techniques have throughout many years been introduced to this end, it is probably fair to say that the…

Machine Learning · Computer Science 2023-05-30 Eduardo J. Aguilar , Valmir C. Barbosa

Recent work on overfitting Bayesian mixtures of distributions offers a powerful framework for clustering multivariate data using a latent Gaussian model which resembles the factor analysis model. The flexibility provided by overfitting…

Methodology · Statistics 2019-08-29 Panagiotis Papastamoulis

Software technology based on reuse is identified as a process of designing software for the reuse purpose. The software reuse is a process in which the existing software is used to build new software. A metric is a quantitative indicator of…

Software Engineering · Computer Science 2013-11-06 M. Bhanu Sridhar , Y. Srinivas , M. H. M. Krishna Prasad