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We use a cluster ensemble to determine the number of clusters, k, in a group of data. A consensus similarity matrix is formed from the ensemble using multiple algorithms and several values for k. A random walk is induced on the graph…

Machine Learning · Statistics 2014-08-06 Shaina Race , Carl Meyer , Kevin Valakuzhy

Recently, it has become feasible to generate large-scale, multi-tissue gene expression data, where expression profiles are obtained from multiple tissues or organs sampled from dozens to hundreds of individuals. When traditional clustering…

Quantitative Methods · Quantitative Biology 2021-10-29 Pau Erola , Johan LM Björkegren , Tom Michoel

Motivation: Clustering is a frequently used concept in variety of bioinformatical applications. We present a new method for hierarchical clustering of data called mutual information clustering (MIC) algorithm. It uses mutual information…

Quantitative Methods · Quantitative Biology 2007-05-23 Alexander Kraskov , Harald Stögbauer , Ralph G. Andrzejak , Peter Grassberger

The K-means algorithm is arguably the most popular data clustering method, commonly applied to processed datasets in some "feature spaces", as is in spectral clustering. Highly sensitive to initializations, however, K-means encounters a…

Machine Learning · Computer Science 2019-06-04 Feiyu Chen , Yuchen Yang , Liwei Xu , Taiping Zhang , Yin Zhang

Clustering, a fundamental activity in unsupervised learning, is notoriously difficult when the feature space is high-dimensional. Fortunately, in many realistic scenarios, only a handful of features are relevant in distinguishing clusters.…

Machine Learning · Statistics 2020-10-23 Zhiyue Zhang , Kenneth Lange , Jason Xu

With the rapid advances of microarray technologies, large amounts of high-dimensional gene expression data are being generated, which poses significant computational challenges. A first step towards addressing this challenge is the use of…

Computer Vision and Pattern Recognition · Computer Science 2013-02-14 P. K. Nizar Banu , H. Hannah Inbarani

High dimensionality in datasets produced by microarray technology presents a challenge for Machine Learning (ML) algorithms, particularly in terms of dimensionality reduction and handling imbalanced sample sizes. To mitigate the explained…

Clustering is a difficult and widely-studied data mining task, with many varieties of clustering algorithms proposed in the literature. Nearly all algorithms use a similarity measure such as a distance metric (e.g. Euclidean distance) to…

Neural and Evolutionary Computing · Computer Science 2019-10-24 Andrew Lensen , Bing Xue , Mengjie Zhang

Biclustering is an unsupervised data mining technique that aims to unveil patterns (biclusters) from gene expression data matrices. In the framework of this thesis, we propose new biclustering algorithms for microarray data. The latter is…

Machine Learning · Computer Science 2018-11-26 Amina Houari

Feature selection is an important and challenging task in high dimensional clustering. For example, in genomics, there may only be a small number of genes that are differentially expressed, which are informative to the overall clustering…

Methodology · Statistics 2019-10-07 Xiangrui Zeng , Hongyu Zheng

In recent work we presented a new approach to the analysis of weighted networks, by providing a straightforward generalization of any network measure defined on unweighted networks. This approach is based on the translation of a weighted…

Data Analysis, Statistics and Probability · Physics 2008-06-05 S. E. Ahnert , D. Garlaschelli , T. M. A. Fink , G. Caldarelli

Motivation: Microarray experiments result in large scale data sets that require extensive mining and refining to extract useful information. We have been developing an efficient novel algorithm for nonmetric multidimensional scaling (nMDS)…

Pattern Formation and Solitons · Physics 2007-05-23 Y-h. Taguchi , Y. Oono

We consider a network of binary-valued sensors with a fusion center. The fusion center has to perform K-means clustering on the binary data transmitted by the sensors. In order to reduce the amount of data transmitted within the network,…

Information Theory · Computer Science 2018-01-18 Elsa Dupraz

The conventional approach for analyzing gene expression data involves clustering algorithms. Cluster analyses provide partitioning of the set of genes that can predict biological classification based on its similarity in n-dimensional…

Molecular Networks · Quantitative Biology 2022-08-23 Jhoirene B. Clemente , Gabriel Besas , Jerick Callado , John Erol Evangelista

Multi-sensor data that track system operating behaviors are widely available nowadays from various engineering systems. Measurements from each sensor over time form a curve and can be viewed as functional data. Clustering of these…

Methodology · Statistics 2024-01-08 Zhongnan Jin , Jie Min , Yili Hong , Pang Du , Qingyu Yang

Purpose: Functional Magnetic Resonance Imaging (fMRI) data acquired through resting-state studies have been used to obtain information about the spontaneous activations inside the brain. One of the approaches for analysis and interpretation…

Image and Video Processing · Electrical Eng. & Systems 2022-02-24 Harshit Parmar , Brian Nutter , Rodney Long , Sameer Antani , Sunanda Mitra

This paper develops a novel hybrid approach for estimating the mixture model of $t$-factor analyzers (MtFA) that employs multivariate $t$-distribution and factor model to cluster and characterize grouped data. The traditional estimation…

Methodology · Statistics 2025-08-06 Kazeem Kareem , Fan Dai

Many clustering methods, including k-means, require the user to specify the number of clusters as an input parameter. A variety of methods have been devised to choose the number of clusters automatically, but they often rely on strong…

Methodology · Statistics 2017-02-10 Wei Fu , Patrick O. Perry

One of the applications of center-based clustering algorithms such as K-Means is partitioning data points into K clusters. In some examples, the feature space relates to the underlying problem we are trying to solve, and sometimes we can…

Machine Learning · Computer Science 2020-09-23 Ali Hassani , Amir Iranmanesh , Mahdi Eftekhari , Abbas Salemi

One of the most popular tools for large scale gene expression studies are high-density oligonucleotide (GeneChip(R)) arrays. These currently have 16-20 small probe cells (``features'') for evaluating the transcript abundance of each gene.…

Biological Physics · Physics 2007-05-23 Felix Naef , Daniel A. Lim , Nila Patil , Marcelo O. Magnasco
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