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Data warehouse architectural choices and optimization techniques are critical to decision support query performance. To facilitate these choices, the performance of the designed data warehouse must be assessed, usually with benchmarks.…

Databases · Computer Science 2017-01-03 Jérôme Darmont , Fadila Bentayeb , Omar Boussaïd

Cancer is a complex disease driven by dynamic regulatory shifts that cannot be fully captured by individual molecular profiling. We employ a data-driven approach to construct a coarse-grained dynamic network model based on hallmark…

Quantitative Methods · Quantitative Biology 2025-02-28 Jiahe Wang , Yan Wu , Yuke Hou , Yang Li , Dachuan Xu , Changjing Zhuge , Yue Han

Ontario (Canada) Health System stakeholders support the idea and necessity of the integrated source of data that would include both clinical (e.g. diagnosis, intervention, length of stay, case mix group) and financial (e.g. cost per…

Computational Engineering, Finance, and Science · Computer Science 2008-02-29 Peter Andru , Alexei Botchkarev

The concept of personalised medicine in cancer therapy is becoming increasingly important. There already exist drugs administered specifically for patients with tumours presenting well-defined mutations. However, the field is still in its…

Biomolecules · Quantitative Biology 2024-08-26 Abbi Abdel-Rehim , Oghenejokpeme Orhobor , Gareth Griffiths , Larisa Soldatova , Ross D. King

We consider the analysis of high dimensional data given in the form of a matrix with columns consisting of observations and rows consisting of features. Often the data is such that the observations do not reside on a regular grid, and the…

Machine Learning · Statistics 2017-08-22 Gal Mishne , Ronen Talmon , Israel Cohen , Ronald R. Coifman , Yuval Kluger

Nowadays, Data Warehouse (DW) plays a crucial role in the process of decision making. However, their design remains a very delicate and difficult task either for expert or users. The goal of this paper is to propose a new approach based on…

Databases · Computer Science 2010-07-15 Nouha Arfaoui , Jalel Akaichi

Identifying subgroups and properties of cancer biopsy samples is a crucial step towards obtaining precise diagnoses and being able to perform personalized treatment of cancer patients. Recent data collections provide a comprehensive…

Genomics · Quantitative Biology 2021-04-23 Stefan Groha , Caroline Weis , Alexander Gusev , Bastian Rieck

Central to the efficacy of prognostics and health management methods is the acquisition and analysis of degradation data, which encapsulates the evolving health condition of engineering systems over time. Degradation data serves as a rich…

Databases · Computer Science 2026-02-06 Fabian Mauthe , Christopher Braun , Julian Raible , Peter Zeiler , Marco F. Huber

Accurate predictions, as with machine learning, may not suffice to provide optimal healthcare for every patient. Indeed, prediction can be driven by shortcuts in the data, such as racial biases. Causal thinking is needed for data-driven…

Cancer prognosis is a critical task that involves predicting patient outcomes and survival rates. To enhance prediction accuracy, previous studies have integrated diverse data modalities, such as clinical notes, medical images, and genomic…

Machine Learning · Computer Science 2025-02-04 Jie Peng , Shuang Zhou , Longwei Yang , Yiran Song , Mohan Zhang , Kaixiong Zhou , Feng Xie , Mingquan Lin , Rui Zhang , Tianlong Chen

Software is vital for the advancement of biology and medicine. Analysis of usage and impact metrics can help developers determine user and community engagement, justify additional funding, encourage additional use, identify unanticipated…

The early development and deployment of hospital and healthcare information systems have encouraged the ongoing digitization of processes in hospitals. Many of these processes, which previously required paperwork and telephone arrangements,…

Computers and Society · Computer Science 2022-09-09 Daniel Schlör , Andreas Hotho

Computational pathology, integrating computational methods and digital imaging, has shown to be effective in advancing disease diagnosis and prognosis. In recent years, the development of machine learning and deep learning has greatly…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Jiamu Wang , Chang-Su Kim , Jin Tae Kwak

As much as data science is playing a pivotal role everywhere, healthcare also finds it prominent application. Breast Cancer is the top rated type of cancer amongst women; which took away 627,000 lives alone. This high mortality rate due to…

Machine Learning · Computer Science 2019-02-26 Vivek Kumar , Brojo Kishore Mishra , Manuel Mazzara , Dang N. H. Thanh , Abhishek Verma

This paper embodies the usage of Big Data in Healthcare. It is important to note that big data in terms of Architecture and implementation might be or has already or will continue to assist the continuous growth in the field of healthcare.…

Cryptography and Security · Computer Science 2019-12-10 Behnam Kiani Kalejahi , Saeed Meshgini , Ayshan Yariyeva , Dawda Ndure , Uzeyir Maharramov , Ali Farzamnia

The continuously increasing cost of the US healthcare system has received significant attention. Central to the ideas aimed at curbing this trend is the use of technology, in the form of the mandate to implement electronic health records…

Information Retrieval · Computer Science 2017-03-24 Pranjul Yadav , Michael Steinbach , Vipin Kumar , Gyorgy Simon

We present a general computational theory of cancer and its developmental dynamics. The theory is based on a theory of the architecture and function of developmental control networks which guide the formation of multicellular organisms.…

Molecular Networks · Quantitative Biology 2011-11-16 Eric Werner

Computational modeling of cancer can help unveil dynamics and interactions that are hard to replicate experimentally. Thanks to the advancement in cancer databases and data analysis technologies, these models have become more robust than…

Quantitative Methods · Quantitative Biology 2023-11-07 Navid Mohammad Mirzaei , Leili Shahriyari

The advancements in data acquisition, storage, and processing techniques have resulted in the rapid growth of heterogeneous medical data. Integrating radiological scans, histopathology images, and molecular information with clinical data is…

Machine Learning · Computer Science 2023-12-25 Aakash Tripathi , Asim Waqas , Kavya Venkatesan , Yasin Yilmaz , Ghulam Rasool

If Electronic Health Records contain a large amount of information about the patients condition and response to treatment, which can potentially revolutionize the clinical practice, such information is seldom considered due to the…

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