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Our work concerns the elucidation of the cancer (epi)genome, transcriptome and proteome to better understand the complex interplay between a cancer cell's molecular state and its response to anti-cancer therapy. To study the problem, we…

Artificial Intelligence · Computer Science 2010-12-09 Matt Holford , James McCusker , Kei Cheung , Michael Krauthammer

In the current technological era, the medical profession has emerged as one of the researchers' favorite subject areas, and cancer is one of them. Because there is now no effective treatment for this illness, it is a matter of concern. Only…

Machine Learning · Computer Science 2024-10-23 Praneeth Kumar T , Nidhi Srivastava , Rakshith Mahishi , Chayadevi M L

The personalized health care service utilizes the relational patient data and big data analytics to tailor the medication recommendations. However, most of the health care data are in unstructured form and it consumes a lot of time and…

Computers and Society · Computer Science 2018-02-13 Sarathkumar Rangarajan , Huai Liu , Hua Wang , Chuan-Long Wang

With the rapid advancements in cancer research, the information that is useful for characterizing disease, staging tumors, and creating treatment and survivorship plans has been changing at a pace that creates challenges when physicians try…

In this paper, we describe a dataset relating to cellular and physical conditions of patients who are operated upon to remove colorectal tumours. This data provides a unique insight into immunological status at the point of tumour removal,…

Machine Learning · Computer Science 2013-07-08 Chris Roadknight , Uwe Aickelin , Alex Ladas , Daniele Soria , John Scholefield , Lindy Durrant

Data warehousing and OLAP applications must nowadays handle complex data that are not only numerical or symbolic. The XML language is well-suited to logically and physically represent complex data. However, its usage induces new theoretical…

We propose there is a need for a technical platform enabling people to engage with the collection, management and consumption of personal data; and that this platform should itself be personal, under the direct control of the individual…

Computers and Society · Computer Science 2015-01-21 Hamed Haddadi , Heidi Howard , Amir Chaudhry , Jon Crowcroft , Anil Madhavapeddy , Richard Mortier

The latest cancer statistics indicate a decrease in cancer-related mortality. However, due to the growing and ageing population, the absolute number of people living with cancer is set to keep increasing. This paper presents ASCAPE, an open…

Healthcare professionals have long envisioned using the enormous processing powers of computers to discover new facts and medical knowledge locked inside electronic health records. These vast medical archives contain time-resolved…

Machine Learning · Computer Science 2020-05-15 Ahmed Allam , Matthias Dittberner , Anna Sintsova , Dominique Brodbeck , Michael Krauthammer

Cancer is a complex disease, the understanding and treatment of which are being aided through increases in the volume of collected data and in the scale of deployed computing power. Consequently, there is a growing need for the development…

The medical research facilitates to acquire a diverse type of data from the same individual for particular cancer. Recent studies show that utilizing such diverse data results in more accurate predictions. The major challenge faced is how…

Genomics · Quantitative Biology 2017-10-11 Jaya Thomas , Lee Sael

Objective: To (1) demonstrate the implementation of a data science platform built on open-source technology within a large, academic healthcare system and (2) describe two computational healthcare applications built on such a platform.…

Today, cancer is one of the leading causes of death throughout the world. This threatening disease has huge negative impacts, not only on quality of life, but also on the healthcare industry, whose resources are already scarce. Thus,…

Computers and Society · Computer Science 2016-06-06 Peter Haddad , Jonathan L. Schaffer , Nilmini Wickramasinghe

The healthcare sector is an important pillar of every community, numerous research studies have been carried out in this context to optimize medical processes and improve care quality and facilitate patient management. In this article we…

Machine Learning · Computer Science 2023-04-04 Chaimae Taoussi , Imad Hafidi , Abdelmoutalib Metrane

Assessing the quality of cancer care administered by US health providers poses numerous challenges due to meaningful heterogeneity in patient populations. Patients undergoing oncology treatment exhibit substantial variation in disease…

Applications · Statistics 2025-02-17 Yige Li , Nancy L. Keating , Mary Beth Landrum , Jose R. Zubizarreta

Requirements engineering is known to be a key factor for the success of software projects. Inside this discipline, goal-oriented requirements engineering approaches have shown specially suitable to deal with projects where it is necessary…

Software Engineering · Computer Science 2009-06-18 Cristina Cachero , Jesús Pardillo

Modern electronic health records (EHRs) provide data to answer clinically meaningful questions. The growing data in EHRs makes healthcare ripe for the use of machine learning. However, learning in a clinical setting presents unique…

Machine Learning · Computer Science 2019-12-09 Marzyeh Ghassemi , Tristan Naumann , Peter Schulam , Andrew L. Beam , Irene Y. Chen , Rajesh Ranganath

This report discusses the issues of data quality in biobanks. It presents the state-of-the-art in data quality: the definition of data quality, the dimensions of data quality, and the quality management system for achieving or describing…

Computers and Society · Computer Science 2018-12-27 Suneth Ranasinghe , Horst Pichler , Johann Eder

A sound performance of health care organizations depends on vigorous financing system, skilled and well paying personnel, trustworthy information, well sustained health services and reliable technologies they used. The management and…

Software Engineering · Computer Science 2017-02-02 Ahmed Mateen , Irum Tariq , Wajiha Azmat

Healthcare information systems deal with a large amount of Personally Identifiable Information related to patients like dates of birth and social security numbers, patients health information and history, and financial information like…

Cryptography and Security · Computer Science 2022-02-15 Sreejith Gopinath , Aspen Olmsted