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We present an alternative domain concerning mathematics to investigate universal evolution mechanisms by focusing on large cycles theory (LCT) - a simplified version of well-known hamiltonian graph theory. LCT joins together a number of…

Combinatorics · Mathematics 2012-12-18 Zh. G. Nikoghosyan

Cells use genetic switches to shift between alternate stable gene expression states, e.g., to adapt to new environments or to follow a developmental pathway. Conceptually, these stable phenotypes can be considered as attractive states on an…

Molecular Networks · Quantitative Biology 2021-06-18 Michael Assaf , Shay Be'er , Elijah Roberts

In the natural world, life has found innumerable ways to survive and often thrive. Between and even within species, each individual is in some manner unique, and this diversity lends adaptability and robustness to life. In this work, we aim…

Machine Learning · Computer Science 2021-07-16 Kenneth Derek , Phillip Isola

A brief introductory overview in general terms is given of concepts, issues and applications of the paradigm of rugged landscapes in the contexts of physics and biology.

Condensed Matter · Physics 2016-08-31 David Sherrington

The fitness landscape encodes the mapping of genotypes to fitness and provides a succinct representation of possible trajectories followed by an evolving population. Evolutionary accessibility is quantified by the existence of…

Populations and Evolution · Quantitative Biology 2021-06-30 Joachim Krug

Evolutionary systems must learn to generalize, often extrapolating from a limited set of selective conditions to anticipate future environmental changes. The mechanisms enabling such generalization remain poorly understood, despite their…

Populations and Evolution · Quantitative Biology 2025-10-29 Federica Ferretti , Mehran Kardar , Arvind Murugan

We propose an extension of the classical variational theory of evolution equations that accounts for dynamics also in possibly non-reflexive and non-separable spaces. The pivoting point is to establish a novel variational structure, based…

Analysis of PDEs · Mathematics 2021-09-17 Alexander Menovschikov , Anastasia Molchanova , Luca Scarpa

We establish an analogy between the Fokker-Planck equation describing evolutionary landscape dynamics and the Schr\"{o}dinger equation which characterizes quantum mechanical particles, showing how a population with multiple genetic traits…

Populations and Evolution · Quantitative Biology 2023-11-07 Vi D. Ao , Duy V. Tran , Kien T. Pham , Duc M. Nguyen , Huy D. Tran , Tuan K. Do , Van H. Do , Trung V. Phan

Dry-land ecosystem has turned into a matter of grave concern, due to growing threat of land degradation and bioproductivity-loss. Self-organized vegetation patterns are a remarkable characteristic of these ecosystems; apart from being…

Populations and Evolution · Quantitative Biology 2022-09-27 Mrinal Kanti Pal , Swarup Poria

Adaptivity is a dynamical feature that is omnipresent in nature, socio-economics, and technology. For example, adaptive couplings appear in various real-world systems like the power grid, social, and neural networks, and they form the…

We discuss the population dynamics with selection and random diffusion, keeping the total population constant, in a fitness landscape associated with Constraint Satisfaction, a paradigm for difficult optimization problems. We obtain a phase…

Populations and Evolution · Quantitative Biology 2016-11-23 Tommaso Brotto , Guy Bunin , Jorge Kurchan

We study possible applications of artificial neural networks to examine the string landscape. Since the field of application is rather versatile, we propose to dynamically evolve these networks via genetic algorithms. This means that we…

High Energy Physics - Theory · Physics 2017-09-13 Fabian Ruehle

Whether or not biodiversity dynamics tend toward stable equilibria remains an unsolved question in ecology and evolution with important implications for our understanding of diversity and its conservation. Phylo/population genetic models…

Populations and Evolution · Quantitative Biology 2017-05-16 A. J. Rominger , I. Overcast , H. Krehenwinkel , R. G. Gillespie , J. Harte , M. J. Hickerson

The existence of complex (multiple-step) genetic adaptations that are "irreducible" (i.e., all partial combinations are less fit than the original genotype) is one of the longest standing problems in evolutionary biology. In standard…

Populations and Evolution · Quantitative Biology 2014-10-17 Meredith V. Trotter , Daniel B. Weissman , Grant I. Peterson , Kayla M. Peck , Joanna Masel

The nature and source of evolutionary trends in complexity is difficult to assess from the fossil record, and the driven vs. passive nature of such trends has been debated for decades. There are also questions about how effectively…

Neural and Evolutionary Computing · Computer Science 2011-12-22 Larry Yaeger , Virgil Griffith , Olaf Sporns

In their well-known textbook (Vincent & Brown, 2005), Vincent and Brown suggested an attractive approach for studying evolutionary dynamics of populations that are heterogeneous with respect to some strategy that affects the fitness of…

Populations and Evolution · Quantitative Biology 2023-02-23 Georgiy Karev

Most theories of evolutionary diversification are based on equilibrium assumptions: they are either based on optimality arguments involving static fitness landscapes, or they assume that populations first evolve to an equilibrium state…

Populations and Evolution · Quantitative Biology 2017-02-07 Iaroslav Ispolatov , Vaibhav Madhok , Michael Doebeli

Motivated by the climate crisis that is currently ravaging the planet, we propose and analyze a novel framework for the evolution of anthropogenic climate impact in which the evolution of human environmental behavior and environmental…

Dynamical Systems · Mathematics 2022-11-22 Kathinka Frieswijk , Lorenzo Zino , A. Stephen Morse , Ming Cao

A framework for the mathematical modeling of evolution in group structured populations is introduced. The population is divided into a fixed large number of groups of fixed size. From generation to generation, new groups are formed that…

Populations and Evolution · Quantitative Biology 2011-06-24 Roberto H. Schonmann , Renato Vicente , Nestor Caticha

The aim of this manuscript is to contain the arguments and define the theoretical objects for building a general framework to model population dynamics from the ground up, relying mainly on the probabilistic landscapes defining the dynamics…

Populations and Evolution · Quantitative Biology 2023-04-26 Gui Araujo
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