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Universality in the behavior of complex systems often reveals itself in the form of scale-invariant distributions that are essentially independent of the details of the microscopic dynamics. A representative paradigm of complex behavior in…

Statistical Mechanics · Physics 2007-05-23 G. Malescio , N. V. Dokholyan , S. V. Buldyrev , H. Eugene Stanley

Learning rules -- prescriptions for updating model parameters to improve performance -- are typically assumed rather than derived. Why do some learning rules work better than others, and under what assumptions can a given rule be considered…

Machine Learning · Computer Science 2025-11-03 John J. Vastola , Samuel J. Gershman , Kanaka Rajan

Systems with a complex dynamics like glasses or models of biological evolution are often pictured in terms of complex landscapes, with a large number of possible collective states. We show on the example of a stochastic spin model with…

Disordered Systems and Neural Networks · Physics 2026-02-03 Laura Guislain , Eric Bertin

Traditionally evolution is seen as a process where from a pool of possible variations of a population (e.g. biological species or industrial goods) a few variations get selected which survive and proliferate, whereas the others vanish.…

Populations and Evolution · Quantitative Biology 2008-09-25 Rudolf Hanel , Stefan Thurner

Proteins evolve through complex sequence spaces, with fitness landscapes serving as a conceptual framework that links sequence to function. Fitness landscapes can be smooth, where multiple similarly accessible evolutionary paths are…

Populations and Evolution · Quantitative Biology 2024-11-21 Mahakaran Sandhu , John Chen , Dana Matthews , Matthew A Spence , Sacha B Pulsford , Barnabas Gall , James Nichols , Nobuhiko Tokuriki , Colin J Jackson

Simple analytic considerations are applied to recently discovered patterns in a generalized Fisher equation for population dynamics. The generalization consists of the inclusion of non-local competition interactions among individuals. We…

Pattern Formation and Solitons · Physics 2007-05-23 M. A. Fuentes , M. N. Kuperman , V. M. Kenkre

On rugged fitness landscapes where sign epistasis is common, adaptation can often involve either individually beneficial "uphill" mutations or more complex mutational trajectories involving fitness valleys or plateaus. The dynamics of the…

Populations and Evolution · Quantitative Biology 2015-10-06 Ian E. Ochs , Michael M. Desai

Epigenetics is most often reduced to chromatin marking in the current literature, whereas this notion was initially defined in a more general context. This restricted view ignores that epigenetic memories are in fact more robustly ensured…

Molecular Networks · Quantitative Biology 2016-09-28 Floriane Nicol-Benoit , Pascale le Goff , Denis Michel

Under the effects of strong genetic drift, it is highly probable to observe gene fixation or loss in a population, shown by divergent probability density functions, or infinite adaptive peaks on a landscape. It is then interesting to ask…

Populations and Evolution · Quantitative Biology 2012-10-29 Song Xu , Shuyun Jiao , Pengyao Jiang , Bo Yuan , Ping Ao

The class of epistatic fitness landscapes is much more diverse than the class of non-epistatic landscapes, and so it stands to reason that there exist dynamical phenomena that can only be realized in the presence of epistasis. Here, we…

Populations and Evolution · Quantitative Biology 2015-03-10 David M. McCandlish , Jakub Otwinowski , Joshua B. Plotkin

We consider a fitness-structured population model with competition and migration between nearest neighbors. Under a combination of large population and rare migration limits we are particularly interested in the asymptotic behavior of the…

Probability · Mathematics 2012-07-20 Anton Bovier , Shi-Dong Wang

Fitness landscapes are a useful concept to study the dynamics of meta-heuristics. In the last two decades, they have been applied with success to estimate the optimization power of several types of evolutionary algorithms, including genetic…

Neural and Evolutionary Computing · Computer Science 2020-01-31 Nuno M. Rodrigues , Sara Silva , Leonardo Vanneschi

Fitness landscapes are mappings between genotypes, phenotypes, and fitness that shape evolution. In recent years, empirical work and theoretical models have greatly advanced our understanding of how populations navigate rugged fitness…

Populations and Evolution · Quantitative Biology 2026-04-21 Malvika Srivastava , Claudia Bank , Joachim Krug , Suman G. Das

We study self-replicating molecules under externally varying conditions. Changing conditions such as temperature variations and/or alterations in the environment's resource composition lead to both non-constant replication and decay rates…

Biological Physics · Physics 2016-09-08 Claus O. Wilke , Christopher Ronnewinkel , Thomas Martinetz

Both evolution and ecology have long been concerned with the impact of variable environmental conditions on observed levels of genetic diversity within and between species. We model the evolution of a quantitative trait under selection that…

Populations and Evolution · Quantitative Biology 2014-11-17 Hannes Svardal , Claus Rueffler , Joachim Hermisson

Evolution has fascinated quantitative and physical scientists for decades: how can the random process of mutation, recombination, and duplication of genetic information generate the diversity of life? What determines the rate of evolution?…

Populations and Evolution · Quantitative Biology 2018-04-23 Richard A. Neher , Aleksandra M. Walczak

Evolution is the process of optimal adaptation of biological populations to their living environments. This is expressed via the concept of fitness, defined as relative reproductive success. However, it has been pointed out that this…

Populations and Evolution · Quantitative Biology 2025-04-17 Luís MA Bettencourt , Brandon J Grandison , Jordan T Kemp

We review the recent fast progress in statistical physics of evolving networks. Interest has focused mainly on the structural properties of random complex networks in communications, biology, social sciences and economics. A number of giant…

Statistical Mechanics · Physics 2015-06-24 S. N. Dorogovtsev , J. F. F. Mendes

Evolution in finite populations is often modelled using the classical Moran process. Over the last ten years this methodology has been extended to structured populations using evolutionary graph theory. An important question in any such…

Populations and Evolution · Quantitative Biology 2015-05-25 Karan Pattni , Mark Broom , Jan Rychtar , Lara J. Silvers

The genotype-fitness map plays a fundamental role in shaping the dynamics of evolution. However, it is difficult to directly measure a fitness landscape in practice, because the number of possible genotypes is astronomical. One approach is…

Populations and Evolution · Quantitative Biology 2014-11-11 Jakub Otwinowski , Joshua B. Plotkin