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In many contemporary statistical and machine learning methods, one needs to optimize an objective function that depends on the discrepancy between two probability distributions. The discrepancy can be referred to as a metric for…

Machine Learning · Computer Science 2025-02-11 Yijin Ni , Xiaoming Huo

We use a suitable version of the so-called "kernel trick" to devise two-sample (homogeneity) tests, especially focussed on high-dimensional and functional data. Our proposal entails a simplification related to the important practical…

Statistics Theory · Mathematics 2024-04-24 Javier Cárcamo , Antonio Cuevas , Luis-Alberto Rodríguez

Cluster analysis is a fundamental research issue in statistics and machine learning. In many modern clustering methods, we need to determine whether two subsets of samples come from the same cluster. Since these subsets are usually…

Machine Learning · Computer Science 2025-07-15 Xinying Liu , Lianyu Hu , Mudi Jiang , Simeng Zhang , Jun Lou , Zengyou He

When analyzing incomplete data, is it better to use multiple imputation (MI) or full information maximum likelihood (ML)? In large samples ML is clearly better, but in small samples ML's usefulness has been limited because ML commonly uses…

Methodology · Statistics 2017-03-24 Paul T. von Hippel

We study two-sample variable selection: identifying variables that discriminate between the distributions of two sets of data vectors. Such variables help scientists understand the mechanisms behind dataset discrepancies. Although…

Machine Learning · Statistics 2025-11-06 Kensuke Mitsuzawa , Motonobu Kanagawa , Stefano Bortoli , Margherita Grossi , Paolo Papotti

Representing, comparing, and measuring the distance between probability distributions is a key task in computational statistics and machine learning. The choice of representation and the associated distance determine properties of the…

Machine Learning · Statistics 2026-02-26 Masha Naslidnyk

Two-sample inference for the difference of population means typically relies upon a Central Limit Theorem approximation. When data are drawn from a Negative Binomial distribution, previous work of Shilane et al. (2010) showed that a Normal…

Methodology · Statistics 2012-03-06 David Shilane , Derek Bean

We introduce a generalized formulation of mutual information (MI) based on the extended Bregman divergence, a framework that subsumes the generalized S-Bregman (GSB) divergence family. The GSB divergence unifies two important classes of…

Methodology · Statistics 2026-02-05 Arijit Pyne

Testing the equality of two conditional distributions is crucial in various modern applications, including transfer learning and causal inference. Despite its importance, this fundamental problem has received surprisingly little attention…

Methodology · Statistics 2025-09-04 Jian Yan , Zhuoxi Li , Xianyang Zhang

Comparing conditional distributions is a fundamental challenge in statistics and machine learning, with applications across a wide range of domains. While proposed methods for measuring discrepancies using kernel embeddings of distributions…

Machine Learning · Statistics 2026-05-05 Peter Moskvichev , Siu Lun Chau , Dino Sejdinovic

The distribution closeness testing (DCT) assesses whether the distance between a distribution pair is at least $\epsilon$-far. Existing DCT methods mainly measure discrepancies between a distribution pair defined on discrete one-dimensional…

Machine Learning · Computer Science 2025-10-10 Zhijian Zhou , Liuhua Peng , Xunye Tian , Feng Liu

The problem of robust binary hypothesis testing is studied. Under both hypotheses, the data-generating distributions are assumed to belong to uncertainty sets constructed through moments; in particular, the sets contain distributions whose…

Statistics Theory · Mathematics 2024-01-09 Akshayaa Magesh , Zhongchang Sun , Venugopal V. Veeravalli , Shaofeng Zou

Distance-based tests, also called "energy statistics", are leading methods for two-sample and independence tests from the statistics community. Kernel-based tests, developed from "kernel mean embeddings", are leading methods for two-sample…

Machine Learning · Statistics 2024-06-27 Cencheng Shen , Joshua T. Vogelstein

Deep neural two-sample tests have recently shown strong power for detecting distributional differences between groups, yet their black-box nature limits interpretability and practical adoption in biomedical analysis. Moreover, most existing…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Masoumeh Javanbakhat , Piotr Komorowski , Dilyara Bareeva , Wei-Chang Lai , Wojciech Samek , Christoph Lippert

This article concerns testing for equality of distribution between groups. We focus on screening variables with shared distributional features such as common support, modes and patterns of skewness. We propose a Bayesian testing method…

Methodology · Statistics 2016-02-19 Eric F. Lock , David B. Dunson

Simultaneously testing $K$ hypotheses while controlling the family-wise error rate is a fundamental problem in statistics. Existing procedures (Bonferroni, Holm, Hochberg, Hommel) provide valid control but sacrifice power, increasingly so…

Methodology · Statistics 2026-04-14 Prasanjit Dubey , Xiaoming Huo

In this paper we introduce a kernel-based measure for detecting differences between two conditional distributions. Using the `kernel trick' and nearest-neighbor graphs, we propose a consistent estimate of this measure which can be computed…

Methodology · Statistics 2024-08-30 Anirban Chatterjee , Ziang Niu , Bhaswar B. Bhattacharya

We propose a two-sample testing procedure based on learned deep neural network representations. To this end, we define two test statistics that perform an asymptotic location test on data samples mapped onto a hidden layer. The tests are…

Machine Learning · Statistics 2020-03-11 Matthias Kirchler , Shahryar Khorasani , Marius Kloft , Christoph Lippert

In this paper new tests for the independence of two high-dimensional vectors are investigated. We consider the case where the dimension of the vectors increases with the sample size and propose multivariate analysis of variance-type…

Statistics Theory · Mathematics 2023-04-19 Taras Bodnar , Holger Dette , Nestor Parolya

We propose a novel adaptive test of goodness-of-fit, with computational cost linear in the number of samples. We learn the test features that best indicate the differences between observed samples and a reference model, by minimizing the…

Machine Learning · Statistics 2017-10-25 Wittawat Jitkrittum , Wenkai Xu , Zoltan Szabo , Kenji Fukumizu , Arthur Gretton
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