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The computational problem of inferring the full haplotype of a cell starting from read sequencing data is known as haplotype assembly, and consists in assigning all heterozygous Single Nucleotide Polymorphisms (SNPs) to exactly one of the…

Matrix inversion problems are often encountered in experimental physics, and in particular in high-energy particle physics, under the name of unfolding. The true spectrum of a physical quantity is deformed by the presence of a detector,…

Machine Learning · Statistics 2020-09-08 Pietro Vischia

De novo genome assembly focuses on finding connections between a vast amount of short sequences in order to reconstruct the original genome. The central problem of genome assembly could be described as finding a Hamiltonian path through a…

Machine Learning · Computer Science 2020-11-11 Lovro Vrček , Petar Veličković , Mile Šikić

Ensembles of artificial neural networks show improved generalization capabilities that outperform those of single networks. However, for aggregation to be effective, the individual networks must be as accurate and diverse as possible. An…

Artificial Intelligence · Computer Science 2007-05-23 P. M. Granitto , P. F. Verdes , H. A. Ceccatto

Biclustering, also known as co-clustering or two-way clustering, simultaneously partitions the rows and columns of a data matrix to reveal submatrices with coherent patterns. Incorporating background knowledge into clustering to enhance…

Optimization and Control · Mathematics 2026-02-24 Antonio M. Sudoso

We propose a clustering-based iterative algorithm to solve certain optimization problems in machine learning, where we start the algorithm by aggregating the original data, solving the problem on aggregated data, and then in subsequent…

Machine Learning · Statistics 2017-01-23 Young Woong Park , Diego Klabjan

A class of two-bit bit flipping algorithms for decoding low-density parity-check codes over the binary symmetric channel was proposed in [1]. Initial results showed that decoders which employ a group of these algorithms operating in…

Information Theory · Computer Science 2012-05-22 Dung Viet Nguyen , Bane Vasic , Michael W. Marcellin

Genetic and comparative genomic studies indicate that extant genomes are more properly considered to be a fusion product of random mutations over generations and genomic material transfers between individuals of different lineages. This has…

Quantitative Methods · Quantitative Biology 2018-01-16 Andreas D. M. Gunawan , Bingxin Lu , Louxin Zhang

Network data appears in very diverse applications, like biological, social, or sensor networks. Clustering of network nodes into categories or communities has thus become a very common task in machine learning and data mining. Network data…

Machine Learning · Computer Science 2020-01-24 Mireille El Gheche , Giovanni Chierchia , Pascal Frossard

Hierarchical clustering is a popular unsupervised data analysis method. For many real-world applications, we would like to exploit prior information about the data that imposes constraints on the clustering hierarchy, and is not captured by…

Data Structures and Algorithms · Computer Science 2018-07-17 Vaggos Chatziafratis , Rad Niazadeh , Moses Charikar

Genome assembly is a fundamental problem in Bioinformatics, requiring to reconstruct a source genome from an assembly graph built from a set of reads (short strings sequenced from the genome). A notion of genome assembly solution is that of…

Discrete Mathematics · Computer Science 2021-11-03 Massimo Cairo , Shahbaz Khan , Romeo Rizzi , Sebastian Schmidt , Alexandru I. Tomescu , Elia C. Zirondelli

Recent advances in DNA sequencing open prospects to make whole-genome analysis rapid and reliable, which is promising for various applications including personalized medicine. However, existing techniques for {\it de novo} genome assembly,…

We present a fast general-purpose algorithm for high-throughput clustering of data "with a two dimensional organization". The algorithm is designed to be implemented with FPGAs or custom electronics. The key feature is a processing time…

Instrumentation and Detectors · Physics 2015-05-14 A. Annovi , M. Beretta

Most graph neural networks follow the message passing mechanism. However, it faces the over-smoothing problem when multiple times of message passing is applied to a graph, causing indistinguishable node representations and prevents the…

Machine Learning · Computer Science 2023-02-06 Yunchong Song , Chenghu Zhou , Xinbing Wang , Zhouhan Lin

Hierarchical clustering of networks consists in finding a tree of communities, such that lower levels of the hierarchy reveal finer-grained community structures. There are two main classes of algorithms tackling this problem. Divisive…

Social and Information Networks · Computer Science 2025-11-25 Maximilien Dreveton , Daichi Kuroda , Matthias Grossglauser , Patrick Thiran

Technical signs of progress during the last decades has led to a situation in which the accumulation of genome sequence data is increasingly fast and cheap. The huge amount of molecular data available nowadays can help addressing new and…

Genomics · Quantitative Biology 2017-05-02 Christophe Guyeux , Bashar Al-Nuaimi , Bassam AlKindy , Jean-François Couchot , Michel Salomon

We study the problem of clustering networks whose nodes have imputed or physical positions in a single dimension, for example prestige hierarchies or the similarity dimension of hyperbolic embeddings. Existing algorithms, such as the…

Social and Information Networks · Computer Science 2023-12-12 Alice Patania , Antoine Allard , Jean-Gabriel Young

The Order Acceptance and Scheduling (OAS) problem describes a class of real-world problems such as in smart manufacturing and satellite scheduling. This problem consists of simultaneously selecting a subset of orders to be processed as well…

Neural and Evolutionary Computing · Computer Science 2021-06-11 Lei He , Arthur Guijt , Mathijs de Weerdt , Lining Xing , Neil Yorke-Smith

A probabilistic clustering algorithm is proposed for the analysis of forensic DNA mixtures in which individual cells are isolated and short tandem repeats are amplified using the polymerase chain reaction to generate single cell…

Applications · Statistics 2025-10-14 Robert G. Cowell

We present a novel hierarchical graph clustering algorithm inspired by modularity-based clustering techniques. The algorithm is agglomerative and based on a simple distance between clusters induced by the probability of sampling node pairs.…

Social and Information Networks · Computer Science 2018-06-25 Thomas Bonald , Bertrand Charpentier , Alexis Galland , Alexandre Hollocou