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This thesis investigates the use of problem-specific knowledge to enhance a genetic algorithm approach to multiple-choice optimisation problems.It shows that such information can significantly enhance performance, but that the choice of…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Uwe Aickelin

While there has been much interest in adapting conventional clustering procedures---and in higher dimensions, persistent homology methods---to directed networks, little is known about the convergence of such methods. In order to even…

Computational Geometry · Computer Science 2022-12-20 Samir Chowdhury , Facundo Mémoli

In recent years, with the development of microarray technique, discovery of useful knowledge from microarray data has become very important. Biclustering is a very useful data mining technique for discovering genes which have similar…

Computational Engineering, Finance, and Science · Computer Science 2009-09-09 Mohsen lashkargir , S. Amirhassan Monadjemi , Ahmad Baraani Dastjerdi

The primary goal in cluster analysis is to discover natural groupings of objects. The field of cluster analysis is crowded with diverse methods that make special assumptions about data and address different scientific aims. Despite its…

Genomics · Quantitative Biology 2018-06-07 Gary K. Chen , Eric Chi , John Ranola , Kenneth Lange

In this paper, we have examined the problem of embedding a cycle of n vertices onto a given set of n points inside a simple polygon. The goal of the problem is that the cycle must be embedded without bends and does not intersect itself and…

Computational Geometry · Computer Science 2022-06-24 Maryam Fadavian , Heidar Fadavian

One of the most widely used techniques for data clustering is agglomerative clustering. Such algorithms have been long used across many different fields ranging from computational biology to social sciences to computer vision in part…

Machine Learning · Computer Science 2014-07-15 Maria-Florina Balcan , Yingyu Liang , Pramod Gupta

Reconciling a gene tree with a species tree is an important task that reveals much about the evolution of genes, genomes, and species, as well as about the molecular function of genes. A wide array of computational tools have been devised…

Populations and Evolution · Quantitative Biology 2012-12-11 Yun Yu , Luay Nakhleh

A new family of codes, called clustering-correcting codes, is presented in this paper. This family of codes is motivated by the special structure of data that is stored in DNA-based storage systems. The data stored in these systems has the…

Information Theory · Computer Science 2019-03-12 Tal Shinkar , Eitan Yaakobi , Andreas Lenz , Antonia Wachter-Zeh

The first step in any genome assembly algorithm entails the conversion from the domain of strings and overlaps to the language of graphs and paths, typically using one of the two conventional methods: de Bruijn graphs or overlap graphs.…

Genomics · Quantitative Biology 2026-04-27 Anton Bankevich

We investigate active learning by pairwise similarity over the leaves of trees originating from hierarchical clustering procedures. In the realizable setting, we provide a full characterization of the number of queries needed to achieve…

Machine Learning · Computer Science 2019-10-15 Fabio Vitale , Anand Rajagopalan , Claudio Gentile

Algorithmic self-assembly, a generalization of crystal growth processes, has been proposed as a mechanism for autonomous DNA computation and for bottom-up fabrication of complex nanostructures. A `program' for growing a desired structure…

Materials Science · Physics 2010-01-08 Rebecca Schulman , Erik Winfree

Matrices are two-dimensional data structures allowing one to conceptually organize information. For example, adjacency matrices are useful to store the links of a network; correlation matrices are simple ways to arrange gene co-expression…

Disordered Systems and Neural Networks · Physics 2022-09-29 Flaviano Morone

Ontology matching is a core task when creating interoperable and linked open datasets. In this paper, we explore a novel structure-based mapping approach which is based on knowledge graph embeddings: The ontologies to be matched are…

Artificial Intelligence · Computer Science 2022-04-11 Jan Portisch , Guilherme Costa , Karolin Stefani , Katharina Kreplin , Michael Hladik , Heiko Paulheim

The aim of this work is to propose a meta-algorithm for automatic classification in the presence of discrete binary classes. Classifier learning in the presence of overlapping class distributions is a challenging problem in machine…

Machine Learning · Statistics 2020-01-22 Vidhi Lalchand

One of the main challenges for hierarchical clustering is how to appropriately identify the representative points in the lower level of the cluster tree, which are going to be utilized as the roots in the higher level of the cluster tree…

Machine Learning · Statistics 2021-11-16 Wen-Bo Xie , Zhen Liu , Jaideep Srivastava

The problem of assembling DNA fragments starting from imperfect strings given by a sequencer, classified as NP hard when trying to get perfect answers, has a huge importance in several fields, because of its relation with the possibility of…

Data Structures and Algorithms · Computer Science 2017-05-26 Juan Manuel Ciro Restrepo , Andrés Felipe Zapata Palacio , Mauricio Toro

No community detection algorithm can be optimal for all possible networks, thus it is important to identify whether the algorithm is suitable for a given network. We propose a multi-step algorithmic solution scheme for overlapping community…

Social and Information Networks · Computer Science 2020-06-24 Tianyi Li , Pan Zhang

Biclustering is a two way clustering approach involving simultaneous clustering along two dimensions of the data matrix. Finding biclusters of web objects (i.e. web users and web pages) is an emerging topic in the context of web usage…

Neural and Evolutionary Computing · Computer Science 2011-06-14 R. Rathipriya , Dr. K. Thangavel , J. Bagyamani

In many applications of clustering (for example, ontologies or clusterings of animal or plant species), hierarchical clusterings are more descriptive than a flat clustering. A hierarchical clustering over $n$ elements is represented by a…

Data Structures and Algorithms · Computer Science 2018-04-18 Ehsan Emamjomeh-Zadeh , David Kempe

We propose a new method for hierarchical clustering based on the optimisation of a cost function over trees of limited depth, and we derive a message--passing method that allows to solve it efficiently. The method and algorithm can be…

Disordered Systems and Neural Networks · Physics 2015-05-14 M. Bailly-Bechet , S. Bradde , A. Braunstein , A. Flaxman , L. Foini , R. Zecchina