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The development of artificial intelligence systems is transitioning from creating static, task-specific models to dynamic, agent-based systems capable of performing well in a wide range of applications. We propose an Interactive Agent…

The human immune system has numerous properties that make it ripe for exploitation in the computational domain, such as robustness and fault tolerance, and many different algorithms, collectively termed Artificial Immune Systems (AIS), have…

Artificial Intelligence · Computer Science 2010-07-05 Julie Greensmith , Amanda Whitbrook , Uwe Aickelin

Agent-based simulators provide granular representations of complex intelligent systems by directly modelling the interactions of the system's constituent agents. Their high-fidelity nature enables hyper-local policy evaluation and testing…

The voter model with memory-dependent dynamics is theoretically and numerically studied at the mean-field level. The `internal age', or time an individual spends holding the same state, is added to the set of binary states of the…

Physics and Society · Physics 2019-09-06 Antonio F. Peralta , Nagi Khalil , Raul Toral

In this paper, the early design of our self-organized agent-based simulation model for exploration of synaptic connections that faithfully generates what is observed in natural situation is given. While we take inspiration from…

Neural and Evolutionary Computing · Computer Science 2012-07-17 Önder Gürcan , Carole Bernon , Kemal S. Türker

Agent-based modeling is a powerful simulation technique to understand the collective behavior and microscopic interaction in complex financial systems. Recently, the concept for determining the key parameters of the agent-based models from…

Statistical Finance · Quantitative Finance 2017-03-21 T. T. Chen , B. Zheng , Y. Li , X. F. Jiang

Many emerging pathogens infect multiple host species, and multi-host pathogens may have very different dynamics in different host species. This research addresses how pathogen replication rates and Immune System (IS) response times are…

Other Quantitative Biology · Quantitative Biology 2009-10-19 Soumya Banerjee , Melanie Moses

User simulation is an emerging interdisciplinary topic with multiple critical applications in the era of Generative AI. It involves creating an intelligent agent that mimics the actions of a human user interacting with an AI system,…

Artificial Intelligence · Computer Science 2026-04-22 Krisztian Balog , ChengXiang Zhai

We investigate numerically the dynamics of three different spin models in the aging regime. Each of these models is meant to be representative of a distinct class of aging behavior: coarsening systems, discontinuous spin glasses, and…

Disordered Systems and Neural Networks · Physics 2009-11-10 Andrea Montanari , Federico Ricci-Tersenghi

This study examined a simulated confined space modelled as a hospital waiting area, where people who could have underlying conditions congregate and mix with potentially infectious individuals. It further investigated the impact of the…

Multiagent Systems · Computer Science 2021-05-24 J. A. Sarumi , E. C. Onwubiko , O. L. A. Ogunjimi

We propose a framework for the description of the effects of vaccinations on the spreading of an epidemic disease. Different vaccines can be dosed, each providing different immunization times and immunization levels. Differences due to…

Analysis of PDEs · Mathematics 2024-07-23 Rinaldo M. Colombo , Mauro Garavello

Understanding cancer cell differentiation is essential for advancing its detection, diagnosis, and treatment. Mathematical models significantly contribute to this by providing a theoretical framework to understand the complex interactions…

Tissues and Organs · Quantitative Biology 2025-08-18 Marcela V. Reale , Gustavo Paccosi , David H. Margarit , Lilia Romanelli

An agent-based model (ABM) is a computational model in which the local interactions of autonomous agents with each other and with their environment give rise to global properties within a given domain. As the detail and complexity of these…

Dynamical Systems · Mathematics 2022-12-01 Daniel A. Cruz , Jack Toppen , Eunbi Park , Melissa L. Kemp , Elena S. Dimitrova

This study offers a new paradigm of individual-level modeling to address the grand challenge of incorporating human behavior in epidemic models. Using generative artificial intelligence in an agent-based epidemic model, each agent is…

Artificial Intelligence · Computer Science 2023-07-12 Ross Williams , Niyousha Hosseinichimeh , Aritra Majumdar , Navid Ghaffarzadegan

Systems biology models are useful models of complex biological systems that may require a large amount of experimental data to fit each model's parameters or to approximate a likelihood function. These models range from a few to thousands…

Quantitative Methods · Quantitative Biology 2024-07-12 Vincent D. Zaballa , Elliot E. Hui

Human-like Agents with diverse and dynamic personalities could serve as an essential design probe in the process of user-centered design, thereby enabling designers to enhance the user experience of interactive applications. In this…

Human-Computer Interaction · Computer Science 2024-06-18 Jiale Li , Jiayang Li , Jiahao Chen , Yifan Li , Shijie Wang , Hugo Zhou , Minjun Ye , Yunsheng Su

The study of system complexity primarily has two objectives: to explore underlying patterns and to develop theoretical explanations. Pattern exploration seeks to clarify the mechanisms behind the emergence of system complexity, while…

Multiagent Systems · Computer Science 2026-02-18 Xiao Xue , Deyu Zhou , Ming Zhang , Xiangning Yu , Fei-Yue Wang

The biological immune system is a robust, complex, adaptive system that defends the body from foreign pathogens. It is able to categorize all cells (or molecules) within the body as self or non-self substances. It does this with the help of…

Neural and Evolutionary Computing · Computer Science 2013-08-26 Uwe Aickelin , Dipankar Dasgupta , Feng Gu

Recently, individual-based models originally used for biological purposes revealed interesting insights into processes of the competition of languages. Within this new field of population dynamics a model considering sexual populations with…

Physics and Society · Physics 2015-06-26 Veit Schwämmle

A model of multicellular systems with several types of cells is developed from the phase field model. The model is presented as a set of partial differential equations of the field variables, each of which expresses the shape of one cell.…

Biological Physics · Physics 2015-05-30 Makiko Nonomura