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Molecular machines transduce free energy between different forms throughout all living organisms. While truly machines in their own right, unlike their macroscopic counterparts molecular machines are characterized by stochastic…

Statistical Mechanics · Physics 2025-06-13 Matthew P. Leighton , David A. Sivak

Motor proteins are active enzymatic molecules that drive a variety of biological processes, including transfer of genetic information, cellular transport, cell motility and muscles contraction. It is known that these biological molecular…

Soft Condensed Matter · Physics 2018-01-17 Luiza V. F. Gomes , Anatoly B. Kolomeisky

We study a minimal quantum Otto heat engine, where the working medium consists of an interacting few-body system in a harmonic trap. This allows us to consider the interaction strength as an additional tunable parameter during the work…

Quantum Physics · Physics 2023-02-10 Mohamed Boubakour , Thomás Fogarty , Thomas Busch

The effect of sequence heterogeneity on the dynamics of molecular motors is reviewed and analyzed using a set of recently introduced lattice models. First, we review results for the influence of heterogenous tracks such as a single-strand…

Statistical Mechanics · Physics 2015-06-25 Yariv Kafri , David R. Nelson

Chemical gradients provide the primordial energy for biological functions by driving the mechanical movement of microscopic engines. Their thermodynamic properties remain elusive, especially concerning the dynamic change in energy demand in…

Statistical Mechanics · Physics 2025-04-01 Ruo-Xun Zhai , Hui Dong

Active matter constantly dissipates energy to power the self-propulsion of its microscopic constituents. This opens the door to designing innovative cyclic engines without any equilibrium equivalent. We offer a consistent thermodynamic…

Soft Condensed Matter · Physics 2020-07-08 Timothy Ekeh , Michael E. Cates , Étienne Fodor

The internal dynamics of strongly interacting systems and that of biomolecules such as proteins display several important analogies, despite the huge difference in their characteristic energy and length scales. For example, in all such…

Biological Physics · Physics 2015-05-30 Pietro Faccioli

The collective behavior of chemically propelled sphere-dimer motors made from linked catalytic and noncatalytic spheres in a quasi-two-dimensional confined geometry is studied using a coarse-grained microscopic dynamical model. Chemical…

Soft Condensed Matter · Physics 2019-01-09 Peter H. Colberg , Raymond Kapral

Molecular motors perform active movements along cytoskeletal filaments and drive the traffic of organelles and other cargo particles in cells. In contrast to the macroscopic traffic of cars, however, the traffic of molecular motors is…

Statistical Mechanics · Physics 2009-12-04 Stefan Klumpp , Melanie J. I. Müller , Reinhard Lipowsky

Nonintegrability plays a crucial role in thermalization and transport processes in many-body Hamiltonian systems, yet its quantitative effects remain unclear. To reveal the connection between the macroscopic relaxation properties and the…

Statistical Mechanics · Physics 2023-10-20 Weicheng Fu , Zhen Wang , Yisen Wang , Yong Zhang , Hong Zhao

Novel organic materials formed from functional molecules are attractive for various nanoelectronic applications because they are environmentally friendly, widely available and inexpensive. Recent advancement in bottom-up fabrication methods…

Mesoscale and Nanoscale Physics · Physics 2022-12-14 Abdalghani Daaoub , Renhang Wang , Ross Davidson , Sara Sangtarash , Hatef Sadeghi

We apply advanced methods of control theory to open quantum systems and we determine finite-time processes which are optimal with respect to thermodynamic performances. General properties and necessary conditions characterizing optimal…

Quantum Physics · Physics 2018-08-01 Vasco Cavina , Andrea Mari , Alberto Carlini , Vittorio Giovannetti

The study of thermal heat engines was pivotal to establishing the principles of equilibrium thermodynamics, with implications far wider than only engine optimization. For nonequilibrium systems, which by definition dissipate energy even at…

Statistical Mechanics · Physics 2021-05-18 Étienne Fodor , Michael E. Cates

The Q-cycle mechanism entering the electron and proton transport chain in oxygenic photosynthesis is an example of how biological processes can be efficiently investigated with elementary microscopic models. Here we address the problem of…

Quantum Physics · Physics 2019-11-21 Francesco Tacchino , Antonella Succurro , Oliver Ebenhöh , Dario Gerace

Intracellular transport of vesicular cargos, organelles, and other macromolecules is an essential process to move large items through a crowded, and inhomogeneous cellular environment. In an effort to dissect the fundamental effects of…

Biomolecules · Quantitative Biology 2014-09-12 Leslie Conway , Jennifer L. Ross

Routinely navigating through an ever-changing and unsteady environment, and utilizing chemical energy, molecular motors transport the cell's crucial components, such as neurotransmitters and organelles. They generate force and pull cargo,…

Biological Physics · Physics 2012-09-28 Bartosz Lisowski , Michał Żabicki

Molecular motors fulfill critical functions within all living beings. Understanding their underlying working principles is therefore of great interest. Here we develop a simple model inspired by the two-component biomolecular motor Fo-F1…

Statistical Mechanics · Physics 2024-12-30 Mathis Grelier , David A. Sivak , Jannik Ehrich

We will study a class of system composed of interacting unicyclic machines placed in contact with a hot and cold thermal baths subjected to a non-conservative driving worksource. Despite their simplicity, these models showcase an intricate…

Statistical Mechanics · Physics 2023-10-19 Iago N. Mamede , Karel Proesmans , Carlos E. Fiore

Nonequilibrium energetics of single molecule translational motor kinesin was investigated by measuring heat dissipation from the violation of the fluctuation-response relation of a probe attached to the motor using optical tweezers. The sum…

Biological Physics · Physics 2023-07-19 Takayuki Ariga , Michio Tomishige , Daisuke Mizuno

We use molecular dynamics simulations to study the dynamics of an ensemble of interacting self-propelled semi-flexible polymers in contact with a thermal bath. Our intention is to model complex systems of biological interest. We find that…

Soft Condensed Matter · Physics 2011-05-06 Davide Loi , Stefano Mossa , Leticia F. Cugliandolo