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Computational Fluid Dynamics (CFD) is currently used to design and improve the hydraulic properties of biomedical devices, wherein the large scale blood circulation needs to be simulated by accounting for the mechanical response of red…

Fluid Dynamics · Physics 2024-12-24 F. Guglietta , M. Behr , L. Biferale , G. Falcucci , M. Sbragaglia

We investigate through numerical simulations the hydrodynamic interactions between two rigid spherical particles suspended on the axis of a cylindrical tube filled with an elastoviscoplastic fluid subjected to pressure-driven flow. The…

In this paper, a multiscale constitutive framework for one-dimensional blood flow modeling is presented and discussed. By analyzing the asymptotic limits of the proposed model, it is shown that different types of blood propagation phenomena…

Numerical Analysis · Mathematics 2023-12-13 Giulia Bertaglia , Lorenzo Pareschi

Discrete simulation methods are efficient tools to investigate the complex behaviors of complex fluids made of either dry granular materials or dilute suspensions. By contrast, materials made of soft and/or concentrated units (emulsions,…

Fluid Dynamics · Physics 2008-12-18 Pierre Rognon , Cyprien Gay

We introduce an innovative lumped-parameter model of the aortic valve, designed to efficiently simulate the impact of valve dynamics on blood flow. Our reduced model includes the elastic effects associated with the leaflets' curvature and…

Numerical Analysis · Mathematics 2025-04-15 Ivan Fumagalli , Luca Dede' , Alfio Quarteroni

We implement molecular dynamics simulations in canonical ensemble to study the effect of confinement on a $2d$ crystal of point particles interacting with an inverse power law potential proportional to $r^{-12}$ in a narrow channel. This…

Soft Condensed Matter · Physics 2014-09-30 M. Ebrahim Foulaadvand , Neda Ojaghlou

When simulating three-dimensional flows interacting with deformable and elastic obstacles, current methods often encounter complexities in the governing equations and challenges in numerical implementation. In this work, we introduce a…

Fluid Dynamics · Physics 2026-01-09 Andreu F. Gallen , Joan Muñoz Biosca , Mario Castro , Aurora Hernández-Machado

Hemodynamics in the aorta from computational fluid dynamics (CFD) simulations can provide a comprehensive analysis of relevant cardiovascular diseases. Coupling the three-element Windkessel model with the patient-specific CFD simulation to…

Fluid Dynamics · Physics 2022-07-14 Zongze Li , Wenbin Mao

In this study, we present a comprehensive numerical analysis of blood flow within human left ventricle models, with particular emphasis on optimizing simulation conditions to enhance the realism and computational efficiency of heart flow…

The steady motion and deformation of a lipid-bilayer vesicle translating through a circular tube in low Reynolds number pressure-driven flow are investigated numerically using an axisymmetric boundary element method. This fluid-structure…

Fluid Dynamics · Physics 2020-05-05 Paul G. Chen , J. M. Lyu , M. Jaeger , M. Leonetti

We exploit a two-dimensional model [7], [6] and [1] describing the elastic behavior of the wall of a flexible blood vessel which takes interaction with surrounding muscle tissue and the 3D fluid flow into account. We study time periodic…

Analysis of PDEs · Mathematics 2021-07-28 V. Kozlov , S. Nazarov , G. Zavorokhin

We investigate crystal nucleation in supersaturated colloid suspensions using enhanced molecular dynamics simulations augmented with machine learning techniques. The simulations reveal that crystallization in the model colloidal system…

Soft Condensed Matter · Physics 2024-04-30 Vanessa J. Meraz , Ziyue Zou , Pratyush Tiwary

This paper outlines a numerical algorithm that could be used for simulating full 3D dynamics of magnetic fluid droplet shapes in external magnetic fields, by solving boundary integral equations. The algorithm works with arbitrary droplet…

Fluid Dynamics · Physics 2022-03-18 Aigars Langins , Andris P. Stikuts , Andrejs Cēbers

Realistic description of patient-specific mechanical properties of clotting dynamics presents a major challenge. Available patient-specific data falls short of robustly characterizing myriads of complex dynamic interactions that happen…

Molecular Networks · Quantitative Biology 2017-05-23 Jayavel Arumugam , Arun Srinivasa

Computer simulations of plasmas are relevant nowadays, because it helps us understand physical processes taking place in the sun and other stellar objects. We developed a program called PCell which is intended for displaying the evolution…

Solar and Stellar Astrophysics · Physics 2015-01-06 Rodrigo Carboni , Francisco Frutos-Alfaro

We investigate a two-dimensional network simulator that model the dynamics of two-phase immiscible bulk flow where film flow can be neglected. We present a method for simulating the detailed dynamical process where the two phases are…

Condensed Matter · Physics 2007-05-23 Henning Arendt Knudsen , Eyvind Aker , Alex Hansen

We propose an improved effective-medium theory to obtain the concentration dependence of the viscosity of particle suspensions at arbitrary volume fractions. Our methodology can be applied, in principle, to any particle shape as long as the…

Soft Condensed Matter · Physics 2010-06-01 I. Santamaria-Holek , Carlos I. Mendoza

Purpose: Hemolysis is a key issue in the design of blood-handling medical devices. Computational prediction of this phenomenon is challenging due to the complex multiscale nature of blood. As a result, conventional approaches often fail to…

Fluid Dynamics · Physics 2026-01-29 Nico Dirkes , Marek Behr

Emergent phenomena share the fascinating property of not being obvious consequences of the design of the system in which they appear. This characteristic is no less relevant when attempting to simulate such phenomena, given that the outcome…

Soft Condensed Matter · Physics 2014-11-26 D. C. Rapaport

Computational cardiovascular flow modeling plays a crucial role in understanding blood flow dynamics. While 3D models provide acute details, they are computationally expensive, especially with fluid-structure interaction (FSI) simulations.…

Fluid Dynamics · Physics 2025-01-06 Hunor Csala , Arvind Mohan , Daniel Livescu , Amirhossein Arzani