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In the small phylogeny problem we, are given a phylogenetic tree and gene orders of the extant species and our goal is to reconstruct all of the ancestral genomes so that the number of evolutionary operations is minimized. Algorithms for…

Populations and Evolution · Quantitative Biology 2015-03-17 Jakub Kováč , Broňa Brejová , Tomáš Vinař

We review the problem of confounding in genetic association studies, which arises principally because of population structure and cryptic relatedness. Many treatments of the problem consider only a simple ``island'' model of population…

Methodology · Statistics 2010-10-25 William Astle , David J. Balding

We sequenced genomes from a $\sim$7,000 year old early farmer from Stuttgart in Germany, an $\sim$8,000 year old hunter-gatherer from Luxembourg, and seven $\sim$8,000 year old hunter-gatherers from southern Sweden. We analyzed these data…

Populations and Evolution · Quantitative Biology 2015-06-18 Iosif Lazaridis , Nick Patterson , Alissa Mittnik , Gabriel Renaud , Swapan Mallick , Karola Kirsanow , Peter H. Sudmant , Joshua G. Schraiber , Sergi Castellano , Mark Lipson , Bonnie Berger , Christos Economou , Ruth Bollongino , Qiaomei Fu , Kirsten I. Bos , Susanne Nordenfelt , Heng Li , Cesare de Filippo , Kay Prüfer , Susanna Sawyer , Cosimo Posth , Wolfgang Haak , Fredrik Hallgren , Elin Fornander , Nadin Rohland , Dominique Delsate , Michael Francken , Jean-Michel Guinet , Joachim Wahl , George Ayodo , Hamza A. Babiker , Graciela Bailliet , Elena Balanovska , Oleg Balanovsky , Ramiro Barrantes , Gabriel Bedoya , Haim Ben-Ami , Judit Bene , Fouad Berrada , Claudio M. Bravi , Francesca Brisighelli , George Busby , Francesco Cali , Mikhail Churnosov , David E. C. Cole , Daniel Corach , Larissa Damba , George van Driem , Stanislav Dryomov , Jean-Michel Dugoujon , Sardana A. Fedorova , Irene Gallego Romero , Marina Gubina , Michael Hammer , Brenna Henn , Tor Hervig , Ugur Hodoglugil , Aashish R. Jha , Sena Karachanak-Yankova , Rita Khusainova , Elza Khusnutdinova , Rick Kittles , Toomas Kivisild , William Klitz , Vaidutis Kučinskas , Alena Kushniarevich , Leila Laredj , Sergey Litvinov , Theologos Loukidis , Robert W. Mahley , Béla Melegh , Ene Metspalu , Julio Molina , Joanna Mountain , Klemetti Näkkäläjärvi , Desislava Nesheva , Thomas Nyambo , Ludmila Osipova , Jüri Parik , Fedor Platonov , Olga Posukh , Valentino Romano , Francisco Rothhammer , Igor Rudan , Ruslan Ruizbakiev , Hovhannes Sahakyan , Antti Sajantila , Antonio Salas , Elena B. Starikovskaya , Ayele Tarekegn , Draga Toncheva , Shahlo Turdikulova , Ingrida Uktveryte , Olga Utevska , René Vasquez , Mercedes Villena , Mikhail Voevoda , Cheryl Winkler , Levon Yepiskoposyan , Pierre Zalloua , Tatijana Zemunik , Alan Cooper , Cristian Capelli , Mark G. Thomas , Andres Ruiz-Linares , Sarah A. Tishkoff , Lalji Singh , Kumarasamy Thangaraj , Richard Villems , David Comas , Rem Sukernik , Mait Metspalu , Matthias Meyer , Evan E. Eichler , Joachim Burger , Montgomery Slatkin , Svante Pääbo , Janet Kelso , David Reich , Johannes Krause

This study analyzes tract-level real estate ownership patterns in New York State (NYS) and New York City (NYC) to uncover racial disparities. We use an advanced race/ethnicity imputation model (LSTM+Geo with XGBoost filtering, validated at…

Computers and Society · Computer Science 2025-06-27 Sanjana Chalavadi , Andrei Pastor , Terry Leitch

In many areas of computational biology, hidden Markov models (HMMs) have been used to model local genomic features. In particular, coalescent HMMs have been used to infer ancient population sizes, migration rates, divergence times, and…

Populations and Evolution · Quantitative Biology 2014-03-05 Kelley Harris , Sara Sheehan , John A. Kamm , Yun S. Song

We consider statistical patterns of variation in growth rates for over 400 species of breeding birds across North America surveyed from 1966 to 1998. We report two results. First, the standard deviation of population growth rates decays as…

Statistical Mechanics · Physics 2007-05-23 Timothy H. Keitt , Luis A. N. Amaral , Sergey V. Buldyrev , H. E. Stanley

This paper measures the skew in how well two families of LLMs represent diverse geographic populations. A spatial probing task is used with geo-referenced corpora to measure the degree to which pre-trained language models from the OPT and…

Computation and Language · Computer Science 2024-03-19 Jonathan Dunn , Benjamin Adams , Harish Tayyar Madabushi

Anonymized electronic medical records are an increasingly popular source of research data. However, these datasets often lack race and ethnicity information. This creates problems for researchers modeling human disease, as race and…

Quantitative Methods · Quantitative Biology 2018-05-01 Ji-Sung Kim , Xin Gao , Andrey Rzhetsky

Knowing where people live is a fundamental component of many decision making processes such as urban development, infectious disease containment, evacuation planning, risk management, conservation planning, and more. While bottom-up, survey…

Artificial Intelligence · Computer Science 2017-08-31 Caleb Robinson , Fred Hohman , Bistra Dilkina

A simple analytical framework to study the molecular quasispecies evolution of finite populations is proposed, in which the population is assumed to be a random combination of the constiyuent molecules in each generation,i.e., linkage…

Statistical Mechanics · Physics 2016-08-31 Domingos Alves , J. F. Fontanari

Many questions that we have about the history and dynamics of organisms have a geographical component: How many are there, and where do they live? How do they move and interbreed across the landscape? How were they moving a thousand years…

Populations and Evolution · Quantitative Biology 2019-11-28 Gideon S. Bradburd , Peter L. Ralph

About 2% of human genetic polymorphisms have been hypothesized to arise via multinucleotide mutations (MNMs), complex events that generate SNPs at multiple sites in a single generation. MNMs have the potential to accelerate the pace at…

Populations and Evolution · Quantitative Biology 2014-04-30 Kelley Harris , Rasmus Nielsen

Recent improvements in high-throughput genotyping and sequencing technologies have afforded the collection of massive, genome-wide datasets of DNA information from hundreds of thousands of individuals. These datasets, in turn, provide…

Populations and Evolution · Quantitative Biology 2014-12-19 Pier Francesco Palamara

Although there has been much interest in estimating divergence and admixture from genomic data, it has proven difficult to distinguish gene flow after divergence from alternative histories involving structure in the ancestral population.…

Populations and Evolution · Quantitative Biology 2013-08-01 Konrad Lohse , Laurent A. F. Frantz

Populations exhibiting partial migration consist of two groups of individuals: Those that mi- grate between habitats, and those that remain fixed in a single habitat. We propose several discrete-time population models to investigate the…

Dynamical Systems · Mathematics 2016-10-31 Anushaya Mohapatra , Haley A. Ohms , David A. Lytle , Patrick De Leenheer

The technological advances in Genetics have given rise to the science of Molecular Genealogy, by giving us the opportunity to approach the study of pedigrees from a new perspective, examining alive people at the same time than collating…

Populations and Evolution · Quantitative Biology 2016-05-23 Bernal Morera

The distribution and heritability of many traits depends on numerous loci in the genome. In general, the astronomical number of possible genotypes makes the system with large numbers of loci difficult to describe. Multilocus evolution,…

Populations and Evolution · Quantitative Biology 2012-08-01 Richard A. Neher , Boris I. Shraiman

As generative AI tools are increasingly used to portray people in professional roles, understanding their racial and gender representational biases is critical. We audit over 1.5 million occupational personas generated by four major large…

Human-Computer Interaction · Computer Science 2026-03-30 Ilona van der Linden , Sahana Kumar , Arnav Dixit , Aadi Sudan , Smruthi Danda , David C. Anastasiu , Kai Lukoff

The quantitative description of cultural evolution is a challenging task. The most difficult part of the problem is probably to find the appropriate measurable quantities that can make more quantitative such evasive concepts as, for…

Physics and Society · Physics 2015-10-01 Paolo Barucca , Jacopo Rocchi , Enzo Marinari , Giorgio Parisi , Federico Ricci-Tersenghi

Background: In the marine environment, where there are few absolute physical barriers, contemporary contact between previously isolated species can occur across great distances, and in some cases, may be inter-oceanic. [..] in the minke…

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