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In the small phylogeny problem we, are given a phylogenetic tree and gene orders of the extant species and our goal is to reconstruct all of the ancestral genomes so that the number of evolutionary operations is minimized. Algorithms for…
We review the problem of confounding in genetic association studies, which arises principally because of population structure and cryptic relatedness. Many treatments of the problem consider only a simple ``island'' model of population…
We sequenced genomes from a $\sim$7,000 year old early farmer from Stuttgart in Germany, an $\sim$8,000 year old hunter-gatherer from Luxembourg, and seven $\sim$8,000 year old hunter-gatherers from southern Sweden. We analyzed these data…
This study analyzes tract-level real estate ownership patterns in New York State (NYS) and New York City (NYC) to uncover racial disparities. We use an advanced race/ethnicity imputation model (LSTM+Geo with XGBoost filtering, validated at…
In many areas of computational biology, hidden Markov models (HMMs) have been used to model local genomic features. In particular, coalescent HMMs have been used to infer ancient population sizes, migration rates, divergence times, and…
We consider statistical patterns of variation in growth rates for over 400 species of breeding birds across North America surveyed from 1966 to 1998. We report two results. First, the standard deviation of population growth rates decays as…
This paper measures the skew in how well two families of LLMs represent diverse geographic populations. A spatial probing task is used with geo-referenced corpora to measure the degree to which pre-trained language models from the OPT and…
Anonymized electronic medical records are an increasingly popular source of research data. However, these datasets often lack race and ethnicity information. This creates problems for researchers modeling human disease, as race and…
Knowing where people live is a fundamental component of many decision making processes such as urban development, infectious disease containment, evacuation planning, risk management, conservation planning, and more. While bottom-up, survey…
A simple analytical framework to study the molecular quasispecies evolution of finite populations is proposed, in which the population is assumed to be a random combination of the constiyuent molecules in each generation,i.e., linkage…
Many questions that we have about the history and dynamics of organisms have a geographical component: How many are there, and where do they live? How do they move and interbreed across the landscape? How were they moving a thousand years…
About 2% of human genetic polymorphisms have been hypothesized to arise via multinucleotide mutations (MNMs), complex events that generate SNPs at multiple sites in a single generation. MNMs have the potential to accelerate the pace at…
Recent improvements in high-throughput genotyping and sequencing technologies have afforded the collection of massive, genome-wide datasets of DNA information from hundreds of thousands of individuals. These datasets, in turn, provide…
Although there has been much interest in estimating divergence and admixture from genomic data, it has proven difficult to distinguish gene flow after divergence from alternative histories involving structure in the ancestral population.…
Populations exhibiting partial migration consist of two groups of individuals: Those that mi- grate between habitats, and those that remain fixed in a single habitat. We propose several discrete-time population models to investigate the…
The technological advances in Genetics have given rise to the science of Molecular Genealogy, by giving us the opportunity to approach the study of pedigrees from a new perspective, examining alive people at the same time than collating…
The distribution and heritability of many traits depends on numerous loci in the genome. In general, the astronomical number of possible genotypes makes the system with large numbers of loci difficult to describe. Multilocus evolution,…
As generative AI tools are increasingly used to portray people in professional roles, understanding their racial and gender representational biases is critical. We audit over 1.5 million occupational personas generated by four major large…
The quantitative description of cultural evolution is a challenging task. The most difficult part of the problem is probably to find the appropriate measurable quantities that can make more quantitative such evasive concepts as, for…
Background: In the marine environment, where there are few absolute physical barriers, contemporary contact between previously isolated species can occur across great distances, and in some cases, may be inter-oceanic. [..] in the minke…