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Movies of human induced pluripotent stem cell (hiPSC)-derived engineered cardiac tissue (microbundles) contain abundant information about structural and functional maturity. However, extracting these data in a reproducible and…

We present a Bayesian framework for learning probabilistic specifications from large, unstructured code corpora, and a method to use this framework to statically detect anomalous, hence likely buggy, program behavior. The distinctive…

Software Engineering · Computer Science 2017-03-07 Vijayaraghavan Murali , Swarat Chaudhuri , Chris Jermaine

Multiple hypothesis testing is a significant problem in nearly all neuroimaging studies. In order to correct for this phenomena, we require a reliable estimate of the Family-Wise Error Rate (FWER). The well known Bonferroni correction…

Computation · Statistics 2015-02-17 Chris Hinrichs , Vamsi K Ithapu , Qinyuan Sun , Sterling C Johnson , Vikas Singh

Graph machine learning models often achieve similar overall performance yet behave differently at the node level, failing on different subsets of nodes with varying reliability. Standard evaluation metrics such as accuracy obscure these…

Machine Learning · Computer Science 2025-09-16 Tianqi Zhao , Russa Biswas , Megha Khosla

Detecting microbial biomarkers used to predict disease phenotypes and clinical outcomes is crucial for disease early-stage screening and diagnosis. Most methods for biomarker identification are linear-based, which is very limited as…

Quantitative Methods · Quantitative Biology 2021-09-29 Jian Jiang

Locks have been widely used as an effective synchronization mechanism among processes and threads. However, we observe that a large number of false inter-thread dependencies (i.e., unnecessary lock contentions) exist during the program…

Programming Languages · Computer Science 2015-04-22 Long Zheng , Xiaofei Liao , Bingsheng He , Song Wu , Hai Jin

Accelerator design languages (ADLs), high-level languages that compile to hardware units, help domain experts quickly design efficient application-specific hardware. ADL compilers optimize datapaths and convert software-like control flow…

Programming Languages · Computer Science 2025-11-26 Ayaka Yorihiro , Griffin Berlstein , Pedro Pontes García , Kevin Laeufer , Adrian Sampson

Consider traffic data (i.e., triplets in the form of source-destination-timestamp) that grow over time. Tensors (i.e., multi-dimensional arrays) with a time mode are widely used for modeling and analyzing such multi-aspect data streams. In…

Machine Learning · Computer Science 2021-03-03 Taehyung Kwon , Inkyu Park , Dongjin Lee , Kijung Shin

Metagenomic taxonomic annotation aims to identify the microbial origins of DNA fragments in environmental samples. Traditional methods that rely on sequence similarity are often constrained by the high microbial diversity and the…

Machine Learning · Computer Science 2026-05-29 Rongye Ye , Lun Li , Zheng Luo , Yiran Zhan , Shuhui Song

Gene set analysis, a popular approach for analyzing high-throughput gene expression data, aims to identify sets of related genes that show significantly enriched or depleted expression patterns between different conditions. In the last…

Mendelian Randomisation (MR) uses genetic variants as instrumental variables to infer causal effects of exposures on an outcome. One key assumption of MR is that the genetic variants used as instrumental variables are independent of the…

Methodology · Statistics 2025-02-21 Maximilian M Mandl , Anne-Laure Boulesteix , Stephen Burgess , Verena Zuber

A crucial problem in genome assembly is the discovery and correction of misassembly errors in draft genomes. We develop a method that will enhance the quality of draft genomes by identifying and removing misassembly errors using paired…

Genomics · Quantitative Biology 2014-11-24 Martin D. Muggli , Simon J. Puglisi , Roy Ronen , Christina Boucher

In this paper we propose a Multiple kernel testing procedure to infer survival data when several factors (e.g. different treatment groups, gender, medical history) and their interaction are of interest simultaneously. Our method is able to…

Methodology · Statistics 2022-06-16 Marc Ditzhaus , Tamara Fernández , Nicolás Rivera

We study verification (decision) problems for graph properties in distributed networks under the locally checkable labeling framework, where nodes use labels (proofs) and local neighborhoods to decide acceptance or rejection. Our focus is…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-03-24 Paweł Garncarek , Tomasz Jurdzinski , Dariusz Kowalski , Subhajit Pramanick

The Triple Pattern Fragment (TPF) approach is de-facto a new way to publish Linked Data at low cost and with high server availability. However, data providers hosting TPF servers are not able to analyze the SPARQL queries they execute…

Databases · Computer Science 2019-06-21 Nassopoulos Georges , Serrano-Alvarado Patricia , Molli Pascal , Desmontils Emmanuel

In modern business modeling and analytics, data monitoring plays a critical role. Nowadays, sophisticated models often rely on hundreds or even thousands of input variables. Over time, structural changes such as abrupt level shifts or trend…

Methodology · Statistics 2019-10-07 Yingbo Li , Robert Cezeaux , Di Yu

Software development life cycle is profoundly influenced by bugs: their introduction, identification, and eventual resolution account for a significant portion of software cost. This has motivated software engineering researchers and…

Software Engineering · Computer Science 2023-03-14 Matthew Jin , Syed Shahriar , Michele Tufano , Xin Shi , Shuai Lu , Neel Sundaresan , Alexey Svyatkovskiy

Traditionally, machine learning methods for PE malware detection have relied on static features like byte histograms, string information, and PE header contents. One barrier to incorporating dynamic analysis features has been the…

Cryptography and Security · Computer Science 2026-05-04 Rebecca Saul , Jingzhi Jiang , Elliott Chia , David Wagner

DL frameworks are the basis of constructing all DL programs and models, and thus their bugs could lead to the unexpected behaviors of any DL program or model relying on them. Such a wide effect demonstrates the necessity and importance of…

Software Engineering · Computer Science 2024-08-22 Junjie Chen , Yihua Liang , Qingchao Shen , Jiajun Jiang , Shuochuan Li

Nature language inference (NLI) task is a predictive task of determining the inference relationship of a pair of natural language sentences. With the increasing popularity of NLI, many state-of-the-art predictive models have been proposed…

Computation and Language · Computer Science 2018-11-13 Haohan Wang , Da Sun , Eric P. Xing