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This paper presents a nonparametric method for estimating the conditional density associated to the jump rate of a piecewise-deterministic Markov process. In our framework, the estimation needs only one observation of the process within a…

Statistics Theory · Mathematics 2012-07-12 Romain Azaïs , François Dufour , Anne Gégout-Petit

Long-range dependence (LRD) has been observed in a variety of phenomena in nature, and for several years also in the spiking activity of neurons. Often, this is interpreted as originating from a non-Markovian system. Here we show that a…

Neurons and Cognition · Quantitative Biology 2018-03-29 Alexandre Richard , Patricio Orio , Etienne Tanré

Estimating the degree of synchrony or reliability between two or more spike trains is a frequent task in both experimental and computational neuroscience. In recent years, many different methods have been proposed that typically compare the…

Biological Physics · Physics 2012-12-11 Thomas Kreuz , Julie S. Haas , Alice Morelli , Henry D. I. Abarbanel , Antonio Politi

The statistical analysis of neuronal spike trains by models of point processes often relies on the assumption of constant process parameters. However, it is a well-known problem that the parameters of empirical spike trains can be highly…

Statistics Theory · Mathematics 2016-12-13 Michael Messer , Kauê M. Costa , Jochen Roeper , Gaby Schneider

Recent literature has found conditional transition rates to be a useful tool for avoiding Markov assumptions in multi-state models. While the estimation of univariate conditional transition rates has been extensively studied, the…

Statistics Theory · Mathematics 2024-08-30 Theis Bathke

The instantaneous state of a neural network consists of both the degree of excitation of each neuron the network is composed of and positions of impulses in communication lines between the neurons. In neurophysiological experiments, the…

Neurons and Cognition · Quantitative Biology 2013-09-10 Kseniia Kravchuk , Alexander Vidybida

We analyze properties of the firing map, which iterations give information about consecutive spikes, for periodically driven linear integrate-and-fire models. By considering locally integrable (thus in general not continuous) input…

Dynamical Systems · Mathematics 2013-04-12 Wacław Marzantowicz , Justyna Signerska

Activity of inhibitory neuron with delayed feedback is considered in the framework of point stochastic processes. The neuron receives excitatory input impulses from a Poisson stream, and inhibitory impulses from the feedback line with a…

Neurons and Cognition · Quantitative Biology 2013-09-10 Alexander K. Vidybida , Kseniya G. Kravchuk

Spiking neural networks (SNNs) are powerful mathematical models that integrate the biological details of neural systems, but their complexity often makes them computationally expensive and analytically untractable. The firing rate of an SNN…

Neurons and Cognition · Quantitative Biology 2025-05-15 Zhongyi Wang , Louis Tao , Zhuo-Cheng Xiao

The instantaneous state of a neural network consists of both the degree of excitation of each neuron, the network is composed of, and positions of impulses in communication lines between neurons. In neurophysiological experiments, the…

Neurons and Cognition · Quantitative Biology 2015-03-17 Kseniya Kravchuk , Alexander Vidybida

We briefly review and highlight the consequences of rigorous and exact results obtained in \cite{cessac:10}, characterizing the statistics of spike trains in a network of leaky Integrate-and-Fire neurons, where time is discrete and where…

Adaptation and Self-Organizing Systems · Physics 2010-08-31 Bruno Cessac , Hassan Nasser , Juan-Carlos Vasquez

We wish to discriminate spike sequences based on the degree of irregularity. For this purpose, we search for a rational expressions of quadratic functions of consecutive interspike intervals that efficiently measures spiking irregularity.…

Neurons and Cognition · Quantitative Biology 2007-05-23 K. Miura , M. Okada , S. Shinomoto

Variability in neural responses is an ubiquitous phenomenon in neurons, usually modeled with stochastic differential equations. In particular, stochastic integrate-and-fire models are widely used to simplify theoretical studies. The…

Neurons and Cognition · Quantitative Biology 2009-06-12 Eugenio Urdapilleta , Ines Samengo

We propose a new abstract formalism for probabilistic timed systems, Parametric Interval Probabilistic Timed Automata, based on an extension of Parametric Timed Automata and Interval Markov Chains. In this context, we consider the…

Formal Languages and Automata Theory · Computer Science 2019-06-13 Étienne André , Benoît Delahaye , Paulin Fournier

A possibly time-dependent transition intensity matrix or generator $(Q(t))$ characterizes the law of a Markov jump process (MP). For a time homogeneous MP, the transition probability matrix (TPM) can be expressed as a matrix exponential of…

Methodology · Statistics 2025-07-23 Dario Gasbarra , Sangita Kulathinal , Etienne Sebag

A piecewise-deterministic Markov process is a stochastic process whose behavior is governed by an ordinary differential equation punctuated by random jumps occurring at random times. We focus on the nonparametric estimation problem of the…

Statistics Theory · Mathematics 2016-05-24 Romain Azaïs , Aurélie Muller-Gueudin

We present a first-order non-homogeneous Markov model for the interspike-interval density of a continuously stimulated spiking neuron. The model allows the conditional interspike-interval density and the stationary interspike-interval…

Neurons and Cognition · Quantitative Biology 2012-08-15 J. Tapson , C. Jin , A. van Schaik , R. Etienne-Cummings

The typical central limit theorems in high-frequency asymptotics for semimartingales are results on stable convergence to a mixed normal limit with an unknown conditional variance. Estimating this conditional variance usually is a hard…

Probability · Mathematics 2020-03-25 Mathias Vetter

Recently, the SPIKE-distance has been proposed as a parameter-free and time-scale independent measure of spike train synchrony. This measure is time-resolved since it relies on instantaneous estimates of spike train dissimilarity. However,…

Data Analysis, Statistics and Probability · Physics 2012-12-11 Thomas Kreuz , Daniel Chicharro , Conor Houghton , Ralph G Andrzejak , Florian Mormann

This paper considers nonparametric estimation and inference in first-order autoregressive (AR(1)) models with deterministically time-varying parameters. A key feature of the proposed approach is to allow for time-varying stationarity in…

Econometrics · Economics 2024-11-04 Donald W. K. Andrews , Ming Li
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