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Objective Neoadjuvant chemotherapy (NACT) is one kind of treatment for advanced stage ovarian cancer patients. However, due to the nature of tumor heterogeneity, the clinical outcomes to NACT vary significantly among different subgroups.…

Computer Vision and Pattern Recognition · Computer Science 2024-07-04 Ke Zhang , Neman Abdoli , Patrik Gilley , Youkabed Sadri , Xuxin Chen , Theresa C. Thai , Lauren Dockery , Kathleen Moore , Robert S. Mannel , Yuchen Qiu

We present an applied study in cancer genomics for integrating data and inferences from laboratory experiments on cancer cell lines with observational data obtained from human breast cancer studies. The biological focus is on improving…

Applications · Statistics 2010-10-07 Daniel Merl , Julia Ling-Yu Chen , Jen-Tsan Chi , Mike West

The advent of digital pathology presents opportunities for computer vision for fast, accurate, and objective solutions for histopathological images and aid in knowledge discovery. This work uses deep learning to predict genomic biomarkers -…

Computer Vision and Pattern Recognition · Computer Science 2021-03-16 Ruchi Chauhan , PK Vinod , CV Jawahar

Detection of minimal residual disease (MRD) in cancer patients after surgery can provide an early marker for disease recurrence and guide subsequent treatment decisions. Accurate and sensitive estimation of tumour burden after cancer…

Imaging biomarkers offer a non-invasive way to predict the response of immunotherapy prior to treatment. In this work, we propose a novel type of deep radiomic features (DRFs) computed from a convolutional neural network (CNN), which…

Computer Vision and Pattern Recognition · Computer Science 2022-06-10 Ahmad Chaddad , Paul Daniel Mingli Zhang , Saima Rathore , Paul Sargos , Christian Desrosiers , Tamim Niazi

The need for more usable and explainable machine learning models in healthcare increases the importance of developing and utilizing causal discovery algorithms, which aim to discover causal relations by analyzing observational data.…

Machine Learning · Computer Science 2023-05-31 Mugariya Farooq , Shahad Hardan , Aigerim Zhumbhayeva , Yujia Zheng , Preslav Nakov , Kun Zhang

This paper presents a novel approach to accurately classify the hallmarks of cancer, which is a crucial task in cancer research. Our proposed method utilizes the Bidirectional Encoder Representations from Transformers (BERT) architecture,…

Computation and Language · Computer Science 2023-06-08 Sultan Zavrak , Seyhmus Yilmaz

Prediction of genetic biomarkers, e.g., microsatellite instability and BRAF in colorectal cancer is crucial for clinical decision making. In this paper, we propose a whole slide image (WSI) based genetic biomarker prediction method via…

Image and Video Processing · Electrical Eng. & Systems 2024-07-16 Ling Zhang , Boxiang Yun , Xingran Xie , Qingli Li , Xinxing Li , Yan Wang

Lesion detection in digital breast tomosynthesis (DBT) is an important and a challenging problem characterized by a low prevalence of images containing tumors. Due to the label scarcity problem, large deep learning models and…

Computer Vision and Pattern Recognition · Computer Science 2022-10-12 Yifan Zhang , Haoyu Dong , Nicholas Konz , Hanxue Gu , Maciej A. Mazurowski

Deep learning algorithms are preferable for rectal tumor segmentation. However, it is still a challenge task to accurately segment and identify the locations and sizes of rectal tumors by using deep learning methods. To increase the…

Image and Video Processing · Electrical Eng. & Systems 2021-01-06 Haijun Gao , Bochuan Zheng , Dazhi Pan , Xiangyin Zeng

Upcoming LCLS-II/II-HE operation at repetition rates approaching 1MHz demands on-detector data reduction to manage the resulting data volumes. We present a 2D discrete wavelet transform (DWT) pre-processing algorithm that segments…

This paper introduces a novel indexing and access method, called Feature- Based Adaptive Tolerance Tree (FATT), using wavelet transform is proposed to organize large image data sets efficiently and to support popular image access mechanisms…

Multimedia · Computer Science 2010-04-09 Dr. P. AnandhaKumar , V. Balamurugan

Feature selection is critical in machine learning to reduce dimensionality and improve model accuracy and efficiency. The exponential growth in feature space dimensionality for modern datasets directly results in ambiguous samples and…

Quantum Physics · Physics 2023-11-30 Haiyan Wang

Recent advances in cancer research largely rely on new developments in microscopic or molecular profiling techniques offering high level of detail with respect to either spatial or molecular features, but usually not both. Here, we present…

In deep networks, the lost data details significantly degrade the performances of image segmentation. In this paper, we propose to apply Discrete Wavelet Transform (DWT) to extract the data details during feature map down-sampling, and…

Computer Vision and Pattern Recognition · Computer Science 2020-06-01 Qiufu Li , Linlin Shen

The development of molecular signatures for the prediction of time-to-event outcomes is a methodologically challenging task in bioinformatics and biostatistics. Although there are numerous approaches for the derivation of marker…

Applications · Statistics 2014-01-09 Andreas Mayr , Matthias Schmid

Automation of feature analysis in the dynamic image frame dataset deals with complexity of intensity mapping with normal and abnormal class. The threshold-based data clustering and feature analysis requires iterative model to learn the…

Computer Vision and Pattern Recognition · Computer Science 2023-01-20 Aatif Jamshed , Bhawna Mallick , Rajendra Kumar Bharti

Breast cancer is a prevalent form of cancer among women, with over 1.5 million women being diagnosed each year. Unfortunately, the survival rates for breast cancer patients in certain third-world countries, like South Africa, are alarmingly…

Computer Vision and Pattern Recognition · Computer Science 2023-06-01 Brennon Maistry , Absalom E. Ezugwu

Deep image registration has demonstrated exceptional accuracy and fast inference. Recent advances have adopted either multiple cascades or pyramid architectures to estimate dense deformation fields in a coarse-to-fine manner. However, due…

Computer Vision and Pattern Recognition · Computer Science 2024-07-19 Xinxing Cheng , Xi Jia , Wenqi Lu , Qiufu Li , Linlin Shen , Alexander Krull , Jinming Duan

Automated brain tumor segmentation plays an important role in the diagnosis and prognosis of the patient. In addition, features from the tumorous brain help in predicting patients overall survival. The main focus of this paper is to segment…

Machine Learning · Computer Science 2019-09-11 Rupal Agravat , Mehul S Raval