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Predicting drug responses using genetic and transcriptomic features is crucial for enhancing personalized medicine. In this study, we implemented an ensemble of machine learning algorithms to analyze the correlation between genetic and…

Genomics · Quantitative Biology 2025-07-04 Johannes Schlüter , Alexander Schönhuth

Background: Apparent Diffusion Coefficient (ADC) values and Total Diffusion Volume (TDV) from Whole-body diffusion-weighted MRI (WB-DWI) are recognized cancer imaging biomarkers. However, manual disease delineation for ADC and TDV…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 A. Candito , A. Dragan , R. Holbrey , A. Ribeiro , R. Donners , C. Messiou , N. Tunariu , D. -M. Koh , M. D. Blackledge

An important goal in cancer research is the survival prognosis of a patient based on a minimal panel of genomic and molecular markers such as genes or proteins. Purely data-driven models without any biological knowledge can produce…

Methodology · Statistics 2025-10-02 Tobias Østmo Hermansen , Manuela Zucknick , Zhi Zhao

Neural networks are capable of learning rich, nonlinear feature representations shown to be beneficial in many predictive tasks. In this work, we use such models to explore different geographical feature representations in the context of…

Machine Learning · Computer Science 2018-09-11 Michael T. Lash , Min Zhang , Xun Zhou , W. Nick Street , Charles F. Lynch

Cancer is a heterogeneous disease with different combinations of genetic and epigenetic alterations driving the development of cancer in different individuals. While these alterations are believed to converge on genes in key cellular…

Quantitative Methods · Quantitative Biology 2015-03-31 Mark D. M. Leiserson , Hsin-Ta Wu , Fabio Vandin , Benjamin J. Raphael

Radiomic features achieve promising results in cancer diagnosis, treatment response prediction, and survival prediction. Our goal is to compare the handcrafted (explicitly designed) and deep learning (DL)-based radiomic features extracted…

The diagnosis and segmentation of tumors using any medical diagnostic tool can be challenging due to the varying nature of this pathology. Magnetic Reso- nance Imaging (MRI) is an established diagnostic tool for various diseases and…

Computer Vision and Pattern Recognition · Computer Science 2017-11-01 Tanvi Gupta , Pranay Manocha , Tapan K. Gandhi , RK Gupta , BK Panigrahi

Breast cancer molecular subtypes classification plays an import role to sort patients with divergent prognosis. The biomarkers used are Estrogen Receptor (ER), Progesterone Receptor (PR), HER2, and Ki67. Based on these biomarkers expression…

Machine Learning · Computer Science 2023-10-24 Matheus del-Valle , Emerson Soares Bernardes , Denise Maria Zezell

Prediction of survivability in a patient for tumor progression is useful to estimate the effectiveness of a treatment protocol. In our work, we present a model to take into account the heterogeneous nature of a tumor to predict survival.…

Convolutional Neural Networks (CNN) have emerged as powerful tools for learning discriminative image features. In this paper, we propose a framework of 3-D fully CNN models for Glioblastoma segmentation from multi-modality MRI data. By…

Computer Vision and Pattern Recognition · Computer Science 2016-11-15 Darvin Yi , Mu Zhou , Zhao Chen , Olivier Gevaert

Pacreatic ductal adenocarcinoma (PDAC) remains one of the most lethal forms of cancer, with a five-year survival rate below 10% primarily due to late detection. This research develops and validates a deep learning framework for early PDAC…

Computer Vision and Pattern Recognition · Computer Science 2025-09-12 Dennis Slobodzian , Amir Kordijazi

DNA methylation is a well-studied genetic modification crucial to regulate the functioning of the genome. Its alterations play an important role in tumorigenesis and tumor-suppression. Thus, studying DNA methylation data may help biomarker…

Genomics · Quantitative Biology 2018-04-16 Fabrizio Celli , Fabio Cumbo , Emanuel Weitschek

Biometric-based identification has drawn a lot of attention in the recent years. Among all biometrics, palmprint is known to possess a rich set of features. In this paper we have proposed to use DCT-based features in parallel with…

Computer Vision and Pattern Recognition · Computer Science 2015-11-30 Shervin Minaee , AmirAli Abdolrashidi

In the domain of Biometrics, recognition systems based on iris, fingerprint or palm print scans etc. are often considered more dependable due to extremely low variance in the properties of these entities with respect to time. However, over…

Computer Vision and Pattern Recognition · Computer Science 2020-09-03 Divya Jyoti , Aman Chadha , Pallavi Vaidya , M. Mani Roja

Early cancer detection remains one of the most critical challenges in modern healthcare, where delayed diagnosis significantly reduces survival outcomes. Recent advancements in artificial intelligence, particularly deep learning, have…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Emmanuella Avwerosuoghene Oghenekaro

Fourier-transform infra-red (FTIR) spectra of samples from 7 plant species were used to explore the influence of preprocessing and feature extraction on efficiency of machine learning algorithms. Wavelet Tensor Train (WTT) and Discrete…

Signal Processing · Electrical Eng. & Systems 2018-07-20 Pavel Kharyuk , Dmitry Nazarenko , Ivan Oseledets

Differentiating the intrinsic subtypes of breast cancer is crucial for deciding the best treatment strategy. Deep learning can predict the subtypes from genetic information more accurately than conventional statistical methods, but to date,…

The continuous wavelet transform (CWT) is very useful for processing signals with intricate and irregular structures in astrophysics and cosmology. It is crucial to propose precise and fast algorithms for the CWT. In this work, we review…

Instrumentation and Methods for Astrophysics · Physics 2024-08-28 Yun Wang , Ping He

This paper presents a method for background removal in experimental data processing using the Dual-Tree Complex Wavelet Transform (DTCWT). The technique is based on discrete wavelet theory (DWT) and addresses limitations of commonly used…

Breast cancer is the most commonly diagnosed cancer in women and a leading cause of cancer death worldwide. Screening mammography reduces mortality, yet interpretation still suffers from substantial false negatives and false positives, and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Charles Fanning , Mehmet Emin Aktas
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