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In high-dimensional genomic data, the curse of dimensionality (d >> n) and limited sampling make feature selection inherently unstable - a critical barrier to biomarker discovery. We introduce StackFeat, an iterative algorithm that…

Other Quantitative Biology · Quantitative Biology 2026-04-28 Akbar Yermekov , D. A. Herrera-Martí

Breast cancer is a significant health concern affecting millions of women worldwide. Accurate survival risk stratification plays a crucial role in guiding personalised treatment decisions and improving patient outcomes. Here we present…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Raktim Kumar Mondol , Ewan K. A. Millar , Arcot Sowmya , Erik Meijering

Continuous Wavelet Transform (CWT) is frequently used for waveform analysis. For example, in the field of neuroscience research, CWT is performed to analyze electroencephalograms (EEG) and calculate the index of brain activity. Recent…

Quantitative Methods · Quantitative Biology 2025-06-10 Shoichiro Nakanishi

In the design of brain-computer interface systems, classification of Electroencephalogram (EEG) signals is the essential part and a challenging task. Recently, as the marginalized discrete wavelet transform (mDWT) representations can reveal…

Machine Learning · Computer Science 2020-02-04 Zhanyu Ma

In this work, we investigate the importance of ethnicity in colorectal cancer survivability prediction using machine learning techniques and the SEER cancer incidence database. We compare model performances for 2-year survivability…

Machine Learning · Computer Science 2019-01-15 Samuel Li , Talayeh Razzaghi

Wavelets are waveform functions that describe transient and unstable variations, such as noises. In this work, we study the advantages of discrete and continuous wavelet transforms (DWT and CWT) of microlensing data to denoise them and…

Instrumentation and Methods for Astrophysics · Physics 2023-10-06 Sedighe Sajadian , Hossein Fatheddin

Wavelet methods are widely used to decompose fMRI, EEG, or MEG signals into time series representing neurophysiological activity in fixed frequency bands. Using these time series, one can estimate frequency-band specific functional…

Neurons and Cognition · Quantitative Biology 2016-09-28 Zitong Zhang , Qawi K. Telesford , Chad Giusti , Kelvin O. Lim , Danielle S. Bassett

Most early-stage colorectal cancer (CRC) patients can be cured by surgery alone, and only certain high-risk early-stage CRC patients benefit from adjuvant chemotherapies. However, very few validated biomarkers are available to accurately…

Machine Learning · Computer Science 2021-11-08 Xingyu Li , Jitendra Jonnagaddala , Shuhua Yang , Hong Zhang , Xu Steven Xu

In this paper, we describe a dataset relating to cellular and physical conditions of patients who are operated upon to remove colorectal tumours. This data provides a unique insight into immunological status at the point of tumour removal,…

Machine Learning · Computer Science 2016-11-17 Chris Roadknight , Uwe Aickelin , Guoping Qiu , John Scholefield , Lindy Durrant

In recent years, the continuous wavelet transform (CWT) has been employed as a spectral feature extractor for acoustic recognition tasks in conjunction with machine learning and deep learning models. However, applying the CWT to each…

Audio and Speech Processing · Electrical Eng. & Systems 2025-12-01 Dang Thoai Phan

Automated detection of breast tumor in early stages using B-Mode Ultrasound image is crucial for preventing widespread breast cancer specially among women. This paper is primarily focusing on the classification of breast tumors through…

Image and Video Processing · Electrical Eng. & Systems 2021-02-12 Shahriar Mahmud Kabir , Md. Sayed Tanveer , ASM Shihavuddin , Mohammed Imamul Hassan Bhuiyan

Colorectal cancer remains a major global health concern, with early detection being pivotal for improving patient outcomes. In this study, we leveraged high throughput methylation profiling of cellfree DNA to identify and validate…

Genomics · Quantitative Biology 2025-05-19 Kartavya Mathur , Shipra Jain , Nisha Bajiya , Nishant Kumar , Gajendra P. S. Raghava

The wavelet spectra is a common starting point for estimating the Hurst exponent of a self-similar signal using wavelet-based techniques. The decay of the $\log_2$ average energy of the detail wavelet coefficients as a function of the level…

Methodology · Statistics 2025-12-02 Raymond J. Hinton, , Pepa Ramírez Cobo , Brani Vidakovic

Breast cancer treatment still remains a challenge, where molecular subtypes classification plays a crucial role in selecting appropriate and specific therapy. The four subtypes are Luminal A (LA), Luminal B (LB), HER2 subtype, and…

Machine Learning · Computer Science 2023-10-24 Matheus del-Valle , Emerson Soares Bernardes , Denise Maria Zezell

Cancer results from genetic alterations that disturb the normal cooperative behavior of cells. Recent high-throughput genomic studies of cancer cells have shown that the mutational landscape of cancer is complex and that individual cancers…

Populations and Evolution · Quantitative Biology 2011-11-10 Niko Beerenwinkel , Tibor Antal , David Dingli , Arne Traulsen , Kenneth W. Kinzler , Victor E. Velculescu , Bert Vogelstein , Martin A. Nowak

Background and Aim: Over-fitting issue has been the reason behind deep learning technology not being successfully implemented in oral cancer images classification. The aims of this research were reducing overfitting for accurately producing…

Image and Video Processing · Electrical Eng. & Systems 2022-08-17 Prakrit Joshi , Omar Hisham Alsadoon , Abeer Alsadoon , Nada AlSallami , Tarik A. Rashid , P. W. C. Prasad , Sami Haddad

Identifying predictive covariates, which forecast individual treatment effectiveness, is crucial for decision-making across different disciplines such as personalized medicine. These covariates, referred to as biomarkers, are extracted from…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Shuhan Xiao , Lukas Klein , Jens Petersen , Philipp Vollmuth , Paul F. Jaeger , Klaus H. Maier-Hein

Due to the potential risk of inducing cancers, radiation dose of X-ray CT should be reduced for routine patient scanning. However, in low-dose X-ray CT, severe artifacts usually occur due to photon starvation, beamhardening, etc, which…

Computer Vision and Pattern Recognition · Computer Science 2018-02-07 Eunhee Kang , Junhong Min , Jong Chul Ye

With the advanced imaging technology, digital pathology imaging of tumor tissue slides is becoming a routine clinical procedure for cancer diagnosis. This process produces massive imaging data that capture histological details in high…

Applications · Statistics 2020-12-10 Esteban Fernández Morales , Cong Zhang , Guanghua Xiao , Chul Moon , Qiwei Li

The work includes a brief overview of the applications of the powerful and easy-to-perform method of Microwave Radiometry (MWR) for the diagnosis of various diseases. The main goal of this paper is to develop a method for diagnosing breast…

Medical Physics · Physics 2024-02-12 Alexander V. Khoperskov , Maxim V. Polyakov
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