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We have learned to live with many potentially deadly viruses for which there is no vaccine, no immunity, and no cure. We do not live in constant fear of these viruses, instead, we have learned how to outsmart them and reduce the harm they…
As infectious disease outbreaks emerge, public health agencies often enact vaccination and social distancing measures to slow transmission. Their success depends on not only strategies and resources, but also public adherence. Individual…
The development of potent drugs for the control of viraemia in people living with HIV means that infected people may live a normal, healthy life and offers the prospect of eliminating HIV transmission in the short term and HIV infection in…
The recent years have seen the emergence of diseases which have spread very quickly all around the world either through human travels like SARS or animal migration like avian flu. Among the biggest challenges raised by infectious emerging…
Background Elimination of malaria can only be achieved through removal of all vectors or complete depletion of the infectious reservoir in humans. Mechanistic models can be built to synthesize diverse observations from the field collected…
Mastitis is a billion dollar health problem for the modern dairy industry, with implications for antibiotic resistance. The use of AI techniques to identify the early onset of this disease, thus has significant implications for the…
The host's odor serves as a critical biological tracking signal in the host-seeking process of mosquitoes, and its heterogeneity significantly influences the transmission of mosquito-borne diseases. In this study, we propose a…
Biological control strategies against mosquito-borne diseases--such as the sterile insect technique (SIT), RIDL, and Wolbachia-based releases--require reliable estimates of dispersal and survival of released males. We propose a…
Multiple Sclerosis (MS) is a chronic and potentially highly disabling disease that can cause permanent damage and deterioration of the central nervous system. In Europe it is the leading cause of non-traumatic disabilities in young adults,…
A central challenge in Human Immunodeficiency Virus (HIV) public health policy lies in determining whether to universally expand treatment access, despite the risk of sub-optimal adherence and consequent drug resistance, or to adopt a more…
The evolution of antibiotic resistance among bacteria threatens our continued ability to treat infectious diseases. The need for sustainable strategies to cure bacterial infections has never been greater. So far, all attempts to restore…
This work introduces a novel epidemiological model that simultaneously considers multiple viral strains, reinfections due to waning immunity response over time and an optimal control formulation. This enables us to derive optimal mitigation…
High-throughput molecular screening is required to investigate the origin and diffusion of antimicrobial resistance in pathogen outbreaks. The most frequent cause of human infection is Escherichia coli, which is dominated by sequence type…
Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory tract infection worldwide, resulting in approximately sixty thousand annual hospitalizations of <5-year-olds in the United States alone and three million annual…
Hospital acquired infections are infections that occur in patients during hospitalization, which were not present at the time of admission. They are among the most common adverse events in healthcare around the world, leading to increased…
A simplified susceptible-infected-recovered (SIR) epidemic model and a small-world model are applied to analyse the spread and control of Severe Acute Respiratory Syndrome (SARS) for Hong Kong in early 2003. From data available in mid April…
A sound performance of health care organizations depends on vigorous financing system, skilled and well paying personnel, trustworthy information, well sustained health services and reliable technologies they used. The management and…
Turkey hosts almost 3.5M refugees and has to face a humanitarian emergency of unprecedented levels. We use mobile phone data to map the mobility patterns of both Turkish and Syrian refugees, and use these patterns to build data-driven…
In the evolving world, we require more additionally the young era to flourish and evolve into developed land. Most of the population all around the world are unaware of the complications involved in the routine they follow while they are…
Antibiotic resistance presents a growing global health threat by diminishing the effectiveness of treatments and allowing once-manageable bacterial infections to persist. This study develops and analyzes an optimization-based mathematical…