English
Related papers

Related papers: Image simulation for biological microscopy: microl…

200 papers

Different imaging modalities are used to extract the diverse information carried in an optical field. Two prominent modalities include bright field and phase contrast microscopy that can visualize the amplitude and phase features of a…

Brillouin microscopy is an emerging optical elastography technique that can be used to assess mechanical properties of biological samples in a 3D, all-optical and hence non-contact fashion. However, the low cross-section of spontaneous…

Optics · Physics 2024-09-04 Carlo Bevilacqua , Robert Prevedel

We propose a new microscopy simulation system that can depict atomistic models in a micrograph visual style, similar to results of physical electron microscopy imaging. This system is scalable, able to represent simulation of electron…

Quantitative Methods · Quantitative Biology 2026-03-27 Ngan Nguyen , Feng Liang , Dominik Engel , Ciril Bohak , Peter Wonka , Timo Ropinski , Ivan Viola

Illumination uniformity is a critical parameter for excitation and data extraction quality in widefield biological imaging applications. However, typical imaging systems suffer from spatial and spectral non-uniformity due to non-ideal…

Optics · Physics 2022-12-14 Iris Celebi , Mete Aslan , M. Selim Unlu

We introduce a structured illumination technique for dark-field x-ray microscopy optimized for three-dimensional imaging of ordered materials at sub-micrometer length scales. Our method utilizes a coded aperture to spatially modulate the…

A near-field microwave imaging system attempts to reveal the presence of an object and/or an electrical property distribution by measuring the scattered field from many positions surrounding the object. Over the past few decades, both the…

Medical Physics · Physics 2019-09-26 Wenyi Shao

Microtomography is a powerful method of materials investigation. It enables to obtain physical properties of porous media non-destructively that is useful in studies. One of the application ways is a calculation of porosity, pore sizes,…

Computational Physics · Physics 2020-07-08 Maxim Grigoriev , Anvar Khafizov , Vladislav Kokhan , Viktor Asadchikov

Live cell culture is crucial in biomedical studies for analyzing cell properties and dynamics in vitro. This study focuses on segmenting unstained live cells imaged with bright-field microscopy. While many segmentation approaches exist for…

Quantitative Methods · Quantitative Biology 2025-08-26 Surajit Das , Gourav Roy , Pavel Zun

Current in vivo microscopy allows us detailed spatiotemporal imaging (3D+t) of complete organisms and offers insights into their development on the cellular level. Even though the imaging speed and quality is steadily improving,…

Image and Video Processing · Electrical Eng. & Systems 2020-01-31 Sourabh Bhide , Ralf Mikut , Maria Leptin , Johannes Stegmaier

Capturing biological specimens at large scales with sub-micron resolution is crucial for biomedical research, but conventional cameras often can't handle the pixel requirements. While most microscopes use motorized stages to move samples…

Optics · Physics 2025-03-28 Charlie Kersuzan , Aymerick Bazin , Amaury Badon

We present DiSH-Sim, a simulator for large discrete models of biological signal transduction pathways, capable of simulating networks with multi-valued elements in both deterministic and stochastic manner. We focus on order of update and…

Molecular Networks · Quantitative Biology 2017-05-09 Khaled Sayed , Yu-Hsin Kuo , Anuva Kulkarni , Natasa Miskov-Zivanov

The acquisition of accurately coloured, balanced images in an optical microscope can be a challenge even for experienced microscope operators. This article presents an entirely automatic mechanism for balancing the white level that allows…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Radoslaw Roszczyk , Artur Krupa , Izabella Antoniuk

Ptychography has become prominent at synchrotron facilities worldwide for characterizing biological and material specimens' topological structures and properties at the nanometer or atomic scale, due to its lens - less, highly quantitative…

Image and Video Processing · Electrical Eng. & Systems 2025-01-28 Tao Liu , Bingyang Wang , JiangTao Zhao , Maik Kahnt , Fucai Zhang

Scanning acoustic microscopy (SAM) has been employed since microscopic images are widely used for biomedical or materials research. Acoustic imaging is an important and well-established method used in nondestructive testing (NDT),…

Image and Video Processing · Electrical Eng. & Systems 2022-08-09 Shubham Kumar Gupta , Azeem Ahmad , Prakhar Kumar , Frank Melandso , Anowarul Habib

Our interest has been to study the effect that scattered radiation has on contrast, signal-to-noise ratio and thickness reconstruction in digital mammographies. Using the GEANT code we have performed Monte-Carlo simulations of 25 kVp Mo/Mo…

Medical Physics · Physics 2009-09-29 Varlen Grabski , Maria-Ester Brandan

X-ray micro tomography is a non-destructive, three-dimensional inspection technique applied across a vast range of fields and disciplines, ranging from research to industrial, encompassing engineering, biology and medical research.…

Hyperspectral imaging is gaining attention in the field of disease diagnosis due to its ability to enhance tissue contrast, surpassing the capabilities of conventional brightfield imaging techniques. Typically, histological sections lack…

Plenoptic imaging enables a light-field to be captured by a single monocular objective lens and an array of micro lenses attached to an image sensor. Metric distances of the light-field's depth planes remain unapparent prior to acquisition.…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Christopher Hahne , Amar Aggoun

A simple, yet general, formalism for the optimized linear combination of astrophysical images is constructed and demonstrated. The formalism allows the user to combine multiple undersampled images to provide oversampled output at high…

Instrumentation and Methods for Astrophysics · Physics 2015-05-28 Barnaby Rowe , Christopher Hirata , Jason Rhodes

Nanophotonic concepts can improve many measurement techniques by enhancing and tailoring the light-matter interaction. However, the optical response of devices that implement such techniques can be intricate, depending on the sample under…