Related papers: Harmonic mean as a determinant of the genetic code
In this short paper, it is shown that the multiplet structure of the standard genetic code is derivable from the total number of nucleotides contained in 64 codons, 192, a small number. The degeneracy class-number is derived as the number…
The standard genetic code multiplet structure as well as the correct degeneracies, class by class, are all extracted from the (unique) number 23, the order of the permutation group of 23 objects.
We develop a simple optimization procedure for assigning binary values to the amino acids. The binary values are determined by a maximization of the degree of pattern conservation in groups of closely related protein sequences. The…
The generation of harmonics by atoms or ions in a two-color, coplanar field configuration with commensurate frequencies is investigated through both, an analytical calculation based on the Lewenstein model and the numerical ab initio…
Protein function depends on both protein structure and amino acid (aa) sequence. Here we show that modular features of both structure and function can be quantified from the aa sequences alone for the small (40,42 aa) plaque-forming amyloid…
The coordinate of a harmonic oscillator is measured at a time chosen at random among three equiprobable instants: now, after one third of the period, or after two thirds. The (total) probability that the outcome is positive depends on the…
This paper deals with the algebraic structure of the sequence of harmonics when combined with equal temperaments. Fractals and the golden ratio appear surprisingly on the way. The sequence of physical harmonics is an increasingly enumerable…
A quaternionic representation of the genetic code, previously reported by the authors, is updated in order to incorporate chirality of nucleotide bases and amino acids. The original representation assigns to each nucleotide base a prime…
Harmonic functions of two variables are exactly those that admit a conjugate, namely a function whose gradient has the same length and is everywhere orthogonal to the gradient of the original function. We show that there are also partial…
We study how generalized Jones $\beta$-numbers relate to harmonic measure. Firstly, we generalize a result of Garnett, Mourgoglou and Tolsa by showing that domains in $\mathbb{R}^{d+1}$ whose boundaries are lower $d$-content regular admit…
Harmonic numbers arise from the truncation of the harmonic series. The $n^\text{th}$ harmonic number is the sum of the reciprocals of each positive integer up to $n$. In addition to briefly introducing the properties of harmonic numbers, we…
Background The theoretical requirements for a genetic code were well defined and modeled by George Gamow and Francis Crick in the 50-es. Their models failed. However the valid Genetic Code, provided by Nirenberg and Matthaei in 1961,…
Living organisms are not just random collections of organic molecules. There is continuous information processing going on in the apparent bouncing around of molecules of life. Optimisation criteria in this information processing can be…
Exchange type chromosome aberrations (ETCAs) are rearrangements of the genome that occur when chromosomes break and the resulting fragments rejoin with other fragments from other chromosomes. ETCAs are commonly observed in cancer cells and…
Human body consists of lot of cells, each cell consist of DeOxaRibo Nucleic Acid (DNA). Identifying the genes from the DNA sequences is a very difficult task. But identifying the coding regions is more complex task compared to the former.…
This work presents a mathematical model that establishes an interesting connection between nucleotide frequencies in human single-stranded DNA and the famous Fibonacci's numbers. The model relies on two assumptions. First, Chargaff's second…
The quantum enveloping algebra U_q(sl(2) \oplus sl(2)) in the limit q \to 0 is proposed as a symmetry algebra for the genetic code. In this approach the triplets of nucleotids or codons in the DNA chain are classified in crystal bases,…
A mathematical algorithm to describe DNA or RNA sequences of $N$ nucleotides by a string of $2N$ integers numbers is presented in the framework of the so called crystal basis model of the genetic code. The description allows to define a not…
We will describe an algorithm to arrange all the positive and negative integer numbers. This array of numbers permits grouping them in six different Classes, $\alpha$, $\beta$, $\gamma$, $\delta$, $\epsilon$, and $\zeta$. Particularly,…
A hypothesis of the evolution of the genetic code is proposed, the leading mechanism of which is the nucleotide spontaneous damage leading to AT-enrichment of the genome. The hypothesis accounts for stability of the genetic code towards…