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Diabetes mellitus is a growing global health issue, with Type 1 Diabetes (T1D) requiring constant monitoring to avoid hypoglycemia. Although Continuous Glucose Monitors (CGMs) are effective, their cost and invasiveness limit access,…

Human-Computer Interaction · Computer Science 2025-09-23 Lawrence Obiuwevwi , Krzysztof J. Rechowicz , Vikas Ashok , Sampath Jayarathna

Artificial Intelligence and Machine Learning (AI/ML) models used in clinical settings are increasingly deployed to support clinical decision-making. However, when training data become stale due to changes in demographics, environment, or…

Artificial Intelligence · Computer Science 2026-04-28 Ioannis Bilionis , Ricardo C. Berrios , Luis Fernandez-Luque , Carlos Castillo

In this paper, we build a new, simple, and interpretable mathematical model to estimate and forecast physiology related to the human glucose-insulin system, constrained by available data. By constructing a simple yet flexible model class…

Quantitative Methods · Quantitative Biology 2022-09-22 M. Sirlanci , M. E. Levine , C. C. Low Wang , D. J. Albers , A. M. Stuart

Diabetes Mellitus (DM) is a chronic disease characterized by an increase in blood glucose (sugar) above normal levels and it appears when human body is not able to produce enough insulin to cover the peripheral tissue demand. Nowadays, DM…

Computers and Society · Computer Science 2020-11-05 Enzo Rucci , Lisandro Delia , Joaquín Pujol , Paula Erbino , Armando De Giusti , Juan José Gagliardino

Objective digital data is scarce yet needed in many domains to enable research that can transform the standard of healthcare. While data from consumer-grade wearables and smartphones is more accessible, there is critical need for similar…

Computers and Society · Computer Science 2023-09-20 Temiloluwa Prioleau , Abigail Bartolome , Richard Comi , Catherine Stanger

Machine learning shows remarkable success for recognizing patterns in data. Here we apply the machine learning (ML) for the diagnosis of early stage diabetes, which is known as a challenging task in medicine. Blood glucose levels are…

Quantitative Methods · Quantitative Biology 2021-02-24 Woo Seok Lee , Junghyo Jo , Taegeun Song

Personal Health Systems (PHS) are mobile solutions tailored to monitoring patients affected by chronic non communicable diseases. A patient affected by a chronic disease can generate large amounts of events. Type 1 Diabetic patients…

Artificial Intelligence · Computer Science 2017-10-04 Stefano Bromuri , Albert Brugues de la Torre , Fabien Duboisson , Michael Schumacher

Patients with Type I Diabetes (T1D) must take insulin injections to prevent the serious long term effects of hyperglycemia - high blood glucose (BG). Patients must also be careful not to inject too much insulin because this could induce…

Machine Learning · Computer Science 2019-04-01 Neil C. Borle , Edmond A. Ryan , Russell Greiner

Glucometers present an important self-monitoring tool for diabetes patients and therefore must exhibit high accu- racy as well as good usability features. Based on an invasive, photometric measurement principle that drastically reduces the…

Applications · Statistics 2016-02-11 Nevine Demitri , Abdelhak M. Zoubir

Intensive care unit (ICU) patients exhibit erratic blood glucose (BG) fluctuations, including hypoglycemic and hyperglycemic episodes, and require exogenous insulin delivery to keep their BG in healthy ranges. Glycemic control via glycemic…

Blood glucose value prediction is an important task in diabetes management. While it is reported that glucose concentration is sensitive to social context such as mood, physical activity, stress, diet, alongside the influence of diabetes…

Machine Learning · Statistics 2019-09-05 Mohammad Akbari , Rumi Chunara

Diabetes is an epidemic disease of the 21st century and is growing globally. Although, final diabetes treatments and cure are still on research phase, related complications of diabetes endanger life of diabetic patients. Diabetic coma which…

Human-Computer Interaction · Computer Science 2016-08-15 Vahid Hosseini

Continuous glucose monitoring (CGM) is central to diabetes care, but explaining CGM patterns clearly and empathetically remains time-intensive. Evidence for retrieval-grounded large language model (LLM) systems in CGM-informed counseling…

Computation and Language · Computer Science 2026-04-17 Zhijun Guo , Alvina Lai , Emmanouil Korakas , Aristeidis Vagenas , Irshad Ahamed , Christo Albor , Hengrui Zhang , Justin Healy , Kezhi Li

Wearable devices, such as actigraphy monitors and continuous glucose monitors (CGMs), capture high-frequency data, which are often summarized by the percentages of time spent within fixed thresholds. For example, actigraphy data are…

Methodology · Statistics 2025-01-22 Junyoung Park , Neo Kok , Irina Gaynanova

Diabetes is a chronic metabolic disorder characterized by persistently high blood glucose levels (BGLs), leading to severe complications such as cardiovascular disease, neuropathy, and retinopathy. Predicting BGLs enables patients to…

Type 1 diabetes (T1D) is an autoimmune disorder that leads to the destruction of insulin-producing cells, resulting in insulin deficiency, as to why the affected individuals depend on external insulin injections. However, insulin can…

Machine Learning · Computer Science 2026-04-27 Beyza Cinar , Maria Maleshkova

The goal of this paper is to propose a new mathematical model for the combined effect of different treatments and lifestyles on the glucose-insulin dynamics of Type 2 diabetes (T2D) patients. The model gives the possibility to take into…

Systems and Control · Electrical Eng. & Systems 2023-01-11 Mohamad Al Ahdab , John Leth , Torben Knudsen , Peter Vestergaard , Henrik Clausen

Diabetes mellitus is a disease that affects to hundreds of millions of people worldwide. Maintaining a good control of the disease is critical to avoid severe long-term complications. In recent years, several artificial pancreas systems…

Neural and Evolutionary Computing · Computer Science 2023-05-09 J. Ignacio Hidalgo , J. Manuel Colmenar , José L. Risco-Martín , Alfredo Cuesta-Infante , Esther Maqueda , Marta Botella , José Antonio Rubio

Prediabetes is a common health condition that often goes undetected until it progresses to type 2 diabetes. Early identification of prediabetes is essential for timely intervention and prevention of complications. This research explores the…

Signal Processing · Electrical Eng. & Systems 2025-04-08 Dimitra Tatli , Vasileios Papapanagiotou , Aris Liakos , Apostolos Tsapas , Anastasios Delopoulos

Here, we develop a mathematical model for glucose-insulin regulatory system. The model includes a new parameter which is the amount of ingested glucose. Ingested glucose is an external glucose source coming from digested food. We assume…

Tissues and Organs · Quantitative Biology 2020-03-06 Sourav Chowdhury , Sourabh Kumar Manna , Suparna Roychowdhury , Indranath Chaudhuri
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