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Spherical multi-layered structures are prevalent in numerous biological systems and engineered applications, including tumor spheroids, layered tissues, and multi-shell nanoparticles for targeted drug delivery. Despite their widespread…

Information Theory · Computer Science 2025-03-19 Mitra Rezaei , Michael Chappell , Adam Noel

We investigate the consensus problem in a network where nodes communicate via diffusion-based molecular communication (DbMC). In DbMC, messages are conveyed via the variation in the concentration of molecules in the medium. Every node…

Information Theory · Computer Science 2011-03-03 Arash Einolghozati , Mohsen Sardari , Ahmad Beirami , Faramarz Fekri

Chemical reactions inside cells are generally considered to happen within fixed-size compartments. Needless to say, cells and their compartments are highly dynamic. Thus, such stringent assumptions may not reflect biochemical reality, and…

Quantitative Methods · Quantitative Biology 2016-02-17 Atiyo Ghosh , Tatiana T. Marquez-Lago

The derivation of suitable analytical models is an important step for the design and analysis of molecular communication systems. However, many existing models have limited applicability in practical scenarios due to various simplifications…

Emerging Technologies · Computer Science 2019-11-28 Maximilian Schäfer , Wayan Wicke , Werner Haselmayr , Rudolf Rabenstein , Robert Schober

Macromolecular crowding in living biological cells effects subdiffusion of larger biomolecules such as proteins and enzymes. Mimicking this subdiffusion in terms of random walks on a critical percolation cluster, we here present a case…

Subcellular Processes · Quantitative Biology 2012-03-09 Leila Esmaeili Sereshki , Michael A. Lomholt , Ralf Metzler

Semantic communication is expected to be one of the cores of next-generation AI-based communications. One of the possibilities offered by semantic communication is the capability to regenerate, at the destination side, images or videos…

Artificial Intelligence · Computer Science 2026-05-18 Eleonora Grassucci , Sergio Barbarossa , Danilo Comminiello

Active transport such as fluid flow is sought in molecular communication to extend coverage, improve reliability, and mitigate interference. Flow models are often over-simplified, assuming one-dimensional diffusion with constant drift.…

Emerging Technologies · Computer Science 2024-10-30 Wayan Wicke , Tobias Schwering , Arman Ahmadzadeh , Vahid Jamali , Adam Noel , Robert Schober

Several enzymes exhibit enhanced diffusion in the presence of a substrate. One explanation of this enhancement arises from fluctuating dimer models, which suggest that enzymes have a higher diffusion constant when interacting with…

Soft Condensed Matter · Physics 2024-05-14 Amit Singh Vishen , Jacques Prost , Madan Rao

Stochastic interactions generically enhance self-diffusivity in living and biological systems, e.g. optimizing navigation strategies and controlling material properties of cellular tissues and bacterial aggregates. Despite this, the…

Soft Condensed Matter · Physics 2024-01-24 Henry Alston , Thibault Bertrand

In this work, we present a paradigm bridging electromagnetic (EM) and molecular communication through a stimuli-responsive intra-body model. It has been established that protein molecules, which play a key role in governing cell behavior,…

Molecular Networks · Quantitative Biology 2020-09-03 Hadeel Elayan , Andrew W. Eckford , Raviraj Adve

Molecular communication is an emerging paradigm for systems that rely on the release of molecules as information carriers. Communication via molecular diffusion is a popular strategy that is ubiquitous in nature and very fast over distances…

Emerging Technologies · Computer Science 2016-09-13 Adam Noel , Dimitrios Makrakis , Abdelhakim Hafid

Classical descriptions of enzyme kinetics ignore the physical nature of the intracellular environment. Main implicit assumptions behind such approaches are that reactions occur in compartment volumes which are large enough so that molecular…

Subcellular Processes · Quantitative Biology 2009-10-26 Ramon Grima

We propose a framework for the derivation and evaluation of distributed iterative algorithms for receiver cooperation in interference-limited wireless systems. Our approach views the processing within and collaboration between receivers as…

Information Theory · Computer Science 2012-04-18 Mihai-Alin Badiu , Carles Navarro Manchón , Vasile Bota , Bernard Henri Fleury

Currently, biological signaling is envisaged as a combination of activation and movement, triggered by local molecular interactions and molecular diffusion, respectively. However, we here suggest, that other fundamental physical mechanisms…

Biological Physics · Physics 2018-05-22 B. Fichtl , I. Silman , M. F. Schneider

Diffusion models (DM) can gradually learn to remove noise, which have been widely used in artificial intelligence generated content (AIGC) in recent years. The property of DM for eliminating noise leads us to wonder whether DM can be…

Information Theory · Computer Science 2023-09-19 Tong Wu , Zhiyong Chen , Dazhi He , Liang Qian , Yin Xu , Meixia Tao , Wenjun Zhang

In diffusion-based molecular communication (DMC), one important functionality of a transmitter nano-machine is signal modulation. In particular, the transmitter has to be able to control the release of signaling molecules for modulation of…

Emerging Technologies · Computer Science 2016-04-20 Hamidreza Arjmandi , Arman Ahmadzadeh , Robert Schober , Masoumeh Nasiri Kenari

A biofilm is a microbial city. It consists of bacteria embedded in an extracellular polymeric substance (EPS) that functions as a protective barrier. Quorum sensing (QS) is a method of bacterial communication, where autoinducers (AIs)…

Signal Processing · Electrical Eng. & Systems 2024-08-15 Yanahan Paramalingam , Hamidreza Arjmandi , Freya Harrison , Tara Schiller , Adam Noel

We construct a new kind of encoder, leveraging the expressive power of diffusion models. In a traditional variational autoencoder, the encoder and decoder jointly negotiate a latent representation of the input. This is made possible by the…

Machine Learning · Computer Science 2026-05-14 Akhil Premkumar , Sarah Lucioni

Diffusion models have shown exceptional scaling properties in the image synthesis domain, and initial attempts have shown similar benefits for applying diffusion to unconditional text synthesis. Denoising diffusion models attempt to…

Audio and Speech Processing · Electrical Eng. & Systems 2022-10-17 Matthew Baas , Kevin Eloff , Herman Kamper

Single-cell studies often show significant phenotypic variability due to the stochastic nature of intra-cellular biochemical reactions. When the numbers of molecules, e.g., transcription factors and regulatory enzymes, are in low abundance,…

Quantitative Methods · Quantitative Biology 2015-06-17 Kyung Hyuk Kim , Hong Qian , Herbert M. Sauro