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Ultra high dose rate electron beams also known as FLASH radiotherapy is becoming of importance in several preclinial cancer treatment studies. However, due to the dose rate used during the irradiation sessions, no real time dose monitoring…

Medical Physics · Physics 2022-08-19 Chloe Lahaye , Jean-Marc Fontbonne , Samuel Salvador

Purpose: Photon counting (PC) computed tomography (CT) can provide material selective CT imaging at lowest patient dose but it suffers from suboptimal count rate. A dynamic beam attenuator (DBA) can help with count rate by modulating x-ray…

Medical Physics · Physics 2016-12-23 Haluk Atak , Polad M. Shikhaliev

The emergence of dielectric bowtie cavities enable optical confinement with ultrahigh quality factor and ultra-small optical mode volumes with perspectives for enhanced light-matter interaction. Experimental work has so far emphasized the…

Background: Spectral shaping is a computed tomography (CT) dose optimization technique that adjusts source voltage and filtration to reduce patient radiation exposure without compromising image quality. Traditionally, radiation dose has…

Cone-beam computed tomography (CBCT) is widely used for image-guided radiotherapy (IGRT). It provides real time visualization at low cost and dose. However, photon scattering and beam hindrance cause artifacts in CBCT. These include…

Medical Physics · Physics 2025-09-29 Alzahra Altalib , Chunhui Li , Alessandro Perelli

Purpose: The purpose of the work was experimental investigations of the breast dose distributions with adaptive filtration. Adaptive filtration reduces detector dynamic range and improves image quality. The adaptive filter with…

Medical Physics · Physics 2017-02-15 Polad M. Shikhaliev

Purpose: Anthropomorphic phantoms can be used in radiotherapy to confirm dose distributions. In this work, a prototype phantom with a deformable chest wall was created based on real human. Methods: A technique similar to 3-dimensional…

Medical Physics · Physics 2021-11-11 Maria Akiki , Fadi Rouphael , Mazen Moussallem

A large number of different feature detectors has been proposed so far. Any existing approach presents strengths and weaknesses, which make a detector optimal only for a limited range of applications. A tool capable of selecting the optimal…

Computer Vision and Pattern Recognition · Computer Science 2016-05-20 Bruno Ferrarini , Shoaib Ehsan , Naveed Ur Rehman , Ales Leonardis , Klaus D. McDonald-Maier

Industrial cone-beam X-ray computed tomography (CT) scans of additively manufactured components produce a 3D reconstruction from projection measurements acquired at multiple predetermined rotation angles of the component about a single…

Image and Video Processing · Electrical Eng. & Systems 2024-07-19 Jingsong Lin , Singanallur Venkatakrishnan , Gregery Buzzard , Amir Koushyar Ziabari , Charles Bouman

Cone-beam computed tomography (CBCT) offers advantages over conventional fan-beam CT in that it requires a shorter time and less exposure to obtain images. CBCT has found a wide variety of applications in patient positioning for…

Computer Vision and Pattern Recognition · Computer Science 2020-07-01 S. Kida , S. Kaji , K. Nawa , T. Imae , T. Nakamoto , S. Ozaki , T. Ohta , Y. Nozawa , K. Nakagawa

Purpose: Grating-based imaging (GBI) and edge-illumination (EI) are two promising types of XPCI as the conventional x-ray sources can be directly utilized. For GBI and EI systems, the phase-stepping acquisition with multiple exposures at a…

Medical Physics · Physics 2022-01-19 Chengpeng Wu , Yuxiang Xing , Li Zhang , Zhiqiang Chen , Xiaohua Zhu , Xi Zhang , Hewei Gao

Photon-counting detector based computed tomography (PCCT) has greatly advanced in recent years. However, spectral inconsistency, referring to inter-pixel variations in detected counts per energy bin, can easily leads to ring or band…

Medical Physics · Physics 2026-01-29 Yuting Chen , Yuxiang Xing , Li Zhang , Zhi Deng , Hewei Gao

Background: Recently, the popularity of dual-layer flat-panel detector (DL-FPD) based dual-energy cone-beam CT (DE-CBCT) imaging has been increasing. However, the image quality of DE-CBCT remains constrained by the Compton scattered X-ray…

We introduce a novel method to design and implement a tunable dynamical tissue phantom for laser speckle-based in-vivo blood flow imaging. This approach relies on Stochastic Differential Equations (SDE) to control a piezoelectric actuator…

Medical Physics · Physics 2024-04-24 Soumyajit Sarkar , K. Murali , Hari M. Varma

Objective Positron emission tomography (PET) allows imaging of patho-physiological information as a form of rate constants from a dynamic image. The rate constant image(s) may be affected from noise on the dynamic image. We introduced an…

Medical Physics · Physics 2023-08-10 Nobuyuki Kudomi , Yukito Maeda

Split-pulse x-ray photon correlation spectroscopy has been proposed as one of the unique capabilities made possible with the x-ray free electron lasers. It enables characterization of atomic scale structural dynamics that dictates the…

Instrumentation and Detectors · Physics 2020-05-06 Yanwen Sun , Mike Dunne , Paul Fuoss , Taito Osaka , Aymeric Robert , Mark Sutton , Makina Yabashi , Diling Zhu

Background: Dual-energy imaging on cone-beam CT (CBCT) scanners has great potential in different clinical applications, including image-guided surgery and adaptive proton therapy. However, the clinical practice of dual-energy CBCT (DE-CBCT)…

Purpose: Cone-beam CT (CBCT) projection images provide anatomical data in real-time over several respiratory cycles, forming a comprehensive picture of tumor movement. We developed and validated a method which uses these projections to…

Medical Physics · Physics 2015-01-15 Bernard L. Jones , David Westerly , Moyed Miften

Background: Limited-angle (LA) dual-energy (DE) cone-beam CT (CBCT) is considered as a potential solution to achieve fast and low-dose DE imaging on current CBCT scanners without hardware modification. However, its clinical implementations…

We describe a method aiming at increasing the dynamic range of X-ray detectors. Two X-ray exposures of an object are acquired at different dose levels and constitute the only input data. The values of the parameters which are needed to…

Medical Physics · Physics 2007-05-23 Evangelos Matsinos , Wolfgang Kaissl
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