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Aging research has produced powerful explanatory frameworks -- evolutionary theories, the Hallmarks of Aging, SENS, geroscience, hyperfunction, and information-loss models -- yet none provides quantitative rules for determining which…

Molecular Networks · Quantitative Biology 2026-05-19 Alex Zhavoronkov

Breast cancer continues to be a significant cause of mortality among women globally. Timely identification and precise diagnosis of breast abnormalities are critical for enhancing patient prognosis. In this study, we focus on improving the…

Image and Video Processing · Electrical Eng. & Systems 2023-12-29 Jun Bai , Annie Jin , Madison Adams , Clifford Yang , Sheida Nabavi

--- Objectives --- Prior to foetal karyotyping, the likelihood of Down's syndrome is often determined combining maternal age, serum free beta-HCG, PAPP-A levels and embryonic measurements of crown-rump length and nuchal translucency for…

Applications · Statistics 2013-02-14 Marc Constant , Viet Chi Tran , Bernard Benoît , Francis Vasseur

Bulk tissue RNA sequencing of heterogeneous samples provides averaged gene expression profiles, obscuring cell type-specific dynamics. To address this, we present a probabilistic hierarchical Bayesian model that deconvolves bulk RNA-seq…

Machine Learning · Computer Science 2025-12-15 Crystal Su , Kuai Yu , Mingyuan Shao , Daniel Bauer

In nuclear medicine, radioiodine therapy is prescribed to treat diseases like hyperthyroidism. The calculation of the prescribed dose depends, amongst other factors, on the thyroid volume. This is currently estimated using conventional 2D…

Robotics · Computer Science 2024-10-28 John Zielke , Christine Eilers , Benjamin Busam , Wolfgang Weber , Nassir Navab , Thomas Wendler

Human age estimation has attracted increasing researches due to its wide applicability in such as security monitoring and advertisement recommendation. Although a variety of methods have been proposed, most of them focus only on the…

Computer Vision and Pattern Recognition · Computer Science 2016-09-14 Qing Tian , Songcan Chen , Xiaoyang Tan

Lambda Virginis (LamVir) is a well-known double-lined spectroscopic Am binary with the interesting property that both stars are very similar in abundance but one is sharp-lined and the other is broad-lined. We present combined…

Up to a factor 1/n!, the volume of a big line bundle agrees with the Euclidean volume of its Okounkov body. The latter is the convex hull of top rank valuation vectors of sections, all with respect to a single flag. In this text we give a…

Algebraic Geometry · Mathematics 2019-03-12 Oliver Braunling

VoxCeleb datasets are widely used in speaker recognition studies. Our work serves two purposes. First, we provide speaker age labels and (an alternative) annotation of speaker gender. Second, we demonstrate the use of this metadata by…

Machine Learning · Computer Science 2021-12-21 Khaled Hechmi , Trung Ngo Trong , Ville Hautamaki , Tomi Kinnunen

Determination of the volume content of ethanol in the alcohol products in practice is usually determined by pycnometry, electronic densimetry, or densimetry using a hydrostatic balance in accordance with Commission Regulation No 2870/2000.…

Chemical Physics · Physics 2014-01-23 Siarhei Charapitsa , Nikita Kulevich , Svetlana Sytova , Yurii Yakuba

The aim of this study is to compare the growth speed of different cell populations measured by their Malthus parameter. We focus on both the age-structured and size-structured equations. A first population (of reference) is composed of…

Probability · Mathematics 2017-03-02 Adélaïde Olivier

Predicting mortality-related outcomes from images offers the prospect of accessible, noninvasive, and scalable health screening. We present a method that leverages pretrained vision transformer foundation models to estimate remaining…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Tristan Kenneweg , Philip Kenneweg , Barbara Hammer

In ecological and environmental contexts, management actions must sometimes be chosen urgently. Value of information (VoI) analysis provides a quantitative toolkit for projecting the improved management outcomes expected after making…

Does bearing children shorten a woman's life expectancy? Several demographic studies, historic and current, have found no such effect. But the Caerphilly cohort study is far the most prominent and frequently-cited, and it answers in the…

Populations and Evolution · Quantitative Biology 2009-04-14 Josh Mitteldorf

Longitudinal biomarker data and cross-sectional outcomes are routinely collected in modern epidemiology studies, often with the goal of informing tailored early intervention decisions. For example, hormones such as estradiol and…

Purpose: To develop a knowledge-based voxel-wise dose prediction system using a convolution neural network for high-dose-rate brachytherapy cervical cancer treatments with a tandem-and-ovoid (T&O) applicator. Methods: A 3D U-NET was…

We use weighted mean and median statistics techniques to combine individual estimates of Omega_m0, the present mean mass density in non-relativistic matter, and determine the observed values and ranges of Omega_m0 from different…

Astrophysics · Physics 2009-11-07 Gang Chen , Bharat Ratra

Human papillomavirus, or HPV, is a sexually transmittable virus infection, which is necessary risk factor for developing cervical cancer, first most common type of cancer in working age women in Moldova. We observe both behavioral change…

Populations and Evolution · Quantitative Biology 2015-04-22 Andrzej Jarynowski

Optical vector analysis (OVA) having the capability to achieve magnitude and phase responses is essential for fabrication and application of emerging optical devices. However, the conventional OVA often have to make compromises among…

Instrumentation and Detectors · Physics 2020-01-17 Ting Qing , Shupeng Li , Zhenzhou Tang , Bindong Gao , Shilong Pan

We introduce a population-age-time (PAT) model which describes the temporal evolution of the population distribution in age. The surprising result is that the qualitative nature of the population distribution dynamics is robust with respect…

Populations and Evolution · Quantitative Biology 2021-11-30 Z. C. Feng , Y. Charles Li