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Exchanges between the blood compartment and the surrounding tissues require a tight regulation by the endothelial barrier. Recent reports inferred that VE-cadherin, an endothelial specific cell-cell adhesion molecule, plays a pivotal role…

Cell Behavior · Quantitative Biology 2008-12-31 Julie Gavard

Understanding the nature of the interface between a biomaterial implant and the biological fluid is an essential step towards creating improved implant materials. This study examined a diamond-like carbon coating biomaterial, the surface…

Materials Science · Physics 2016-11-16 Reece N. Oosterbeek , Christopher K. Seal , Margaret M. Hyland

This study reveals the essence of ligand recognition mechanisms by which calmodulin (CaM) controls a variety of Ca2+ signaling processes. We study eight forms of calcium-loaded CaM each with distinct conformational states. Reducing the…

Biological Physics · Physics 2011-07-12 Ali Rana Atilgan , Ayse Ozlem Aykut , Canan Atilgan

Making use of a simplified model for protein folding, it can be shown that conformations which are particularly stable when their energy is minimized with respect to amino acid sequence (in the sense that they display a large energy gap to…

Soft Condensed Matter · Physics 2007-05-23 R. A. Broglia , G. Tiana , H. E. Roman

A systematic analysis of the ground state and fission properties of actinides and superheavy nuclei important for the $r$ process modeling has been performed within the framework of covariant density functional theory for the first time in…

Nuclear Theory · Physics 2022-03-10 A. V. Afanasjev , A. Taninah

Protein solubility and conformational stability are a result of a balance of interactions both within a protein and between protein and solvent. The electrostatic solvation free energy of oligoglycines, models for the peptide backbone,…

Soft Condensed Matter · Physics 2016-03-24 D. Karandur , B. M. Pettitt

Chitin and protein are two main building blocks for many natural biomaterials. The interaction between chitin and protein critically determines the properties of the composite biological materials. As living organisms usually encounter…

Materials Science · Physics 2016-07-26 Zechuan Yu , Denvid Lau

The last two decades, in particular, have witnessed a large volume of research revolving around structure-property correlation in Carbon based nanocomposites, synthesized by several methods.In the simplest of terms, the electronic…

Materials Science · Physics 2021-10-07 Manab Mallik , Mainak Saha

While modern structural biology has provided us with a rich and diverse picture of membrane proteins, the biological function of membrane proteins is often influenced by the mechanical properties of the surrounding lipid bilayer. Here we…

Biomolecules · Quantitative Biology 2013-05-27 Christoph A. Haselwandter , Rob Phillips

We investigated the effect of mean-field electron correlations on the band electronic structure of Co, Ni, and Pd ultra-thin monatomic nanowires, at the breaking point, by means of density-functional calculations in the self-interaction…

Materials Science · Physics 2009-11-10 Malgorzata Wierzbowska , Anna Delin , Erio Tosatti

Protein folding cooperativity is defined by the nature of the finite-size thermodynamic transition exhibited upon folding: two-state transitions show a free energy barrier between the folded and unfolded ensembles, while downhill folding is…

Biomolecules · Quantitative Biology 2017-08-23 Tristan Bereau , Michael Bachmann , Markus Deserno

We report first study of transverse momentum ($p_\mathrm{T}$) spectra for $\pi^{\pm}$, $K^{\pm}$, $p$, and $\bar{p}$ in isobar, $^{96}_{44}$Ru+$^{96}_{44}$Ru and $^{96}_{40}$Zr+$^{96}_{40}$Zr, collisions at $\sqrt{s_{\mathrm{NN}}} = 200$…

High Energy Physics - Phenomenology · Physics 2024-07-11 P. Sinha , V. Bairathi , K. Gopal , C. Jena , S. Kabana

Protein-protein interactions (protein functionalities) are mediated by water, which compacts individual proteins and promotes close and temporarily stable large-area protein-protein interfaces. Proteins are peptide chains decorated by amino…

Soft Condensed Matter · Physics 2008-02-26 J. C. Phillips

Purpose: In treatment planning of charged-particle radiotherapy, patient heterogeneity is conventionally modeled as variable-density water converted from CT images to best reproduce the stopping power, which may lead to inaccuracies in the…

Medical Physics · Physics 2013-01-08 Nobuyuki Kanematsu , Taku Inaniwa , Yusuke Koba

Models of protein energetics which neglect interactions between amino acids that are not adjacent in the native state, such as the Go model, encode or underlie many influential ideas on protein folding. Implicit in this simplification is a…

Biomolecules · Quantitative Biology 2009-10-08 Brian C. Gin , Juan P. Garrahan , Phillip L. Geissler

The present work continues our previous studies of pom-pom molecule [K. Haydukivska, O. Kalyuzhnyi, V. Blavatska, and J. Ilnytskyi, J. Mol. Liq. 328, 115456 (2021); Condens. Matter Phys. 25, 23302 (2022)]. The molecule consists of a linear…

Soft Condensed Matter · Physics 2023-05-26 K. Haydukivska , V. Blavatska

We present a structural data set of the 20 proteinogenic amino acids and their amino-methylated and acetylated (capped) dipeptides. Different protonation states of the backbone (uncharged and zwitterionic) were considered for the amino…

Biomolecules · Quantitative Biology 2016-01-12 Matti Ropo , Markus Schneider , Carsten Baldauf , Volker Blum

Short-range interactions and long-range contacts drive the 3D folding of structured proteins. The proteins' structure has a direct impact on their biological function. However, nearly 40% of the eukaryotes proteome is composed of…

The formation of monodisperse, tunable sized, alloyed nanoparticles of Ni, Co, or Fe with Pt and pure Pt nanoparticles attached to carbon nanotubes has been investigated. Following homogeneous nucleation, nanoparticles attach directly to…

Morphology of polymer electrolytes membranes (PEM), e.g., Nafion, inside PEM fuel cell catalyst layers has significant impact on the electrochemical activity and transport phenomena that determine cell performance. In those regions, Nafion…

Materials Science · Physics 2015-01-27 Daiane Damasceno Borges , Gerard Gebel , Alejandro A. Franco , Kourosh Malek , Stefano Mossa
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