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It is expected that atomic vacancies or nanometric cavities reduce the number of chemical bonds of nearby atoms and hence the strength of a voided solid. However, the hardness of a porous specimen does not always follow this simple picture…

Mesoscale and Nanoscale Physics · Physics 2008-01-08 Chang Q. Sun

While all the information required for the folding of a protein is contained in its amino acid sequence, one has not yet learned how to extract this information to predict the three--dimensional, biologically active, native conformation of…

Biomolecules · Quantitative Biology 2009-11-10 R. A. Broglia , G. Tiana

A protein's function depends critically on its conformational ensemble, a collection of energy weighted structures whose balance depends on temperature and environment. Though recent deep learning (DL) methods have substantially advanced…

Biomolecules · Quantitative Biology 2026-01-09 Myeongsang Lee , Lauren L. Porter

Nanoparticles can influence the properties of polymer materials by a variety of mechanisms. With fullerene, carbon nanotube, and clay or graphene sheet nanocomposites in mind, we investigate how particle shape influences the melt shear…

Materials Science · Physics 2015-06-25 Scott T. Knauert , Jack F. Douglas , Francis W. Starr

We study statistical properties of interacting protein-like surfaces and predict two strong, related effects: (i) statistically enhanced self-attraction of proteins; (ii) statistically enhanced attraction of proteins with similar…

Biomolecules · Quantitative Biology 2007-05-23 D. B. Lukatsky , B. E. Shakhnovich , J. Mintseris , E. I. Shakhnovich

We investigate vibration modes and their Raman activity of single-walled carbon nanotubes that are bent within their intrinsic elastic limits. By implementing novel boundary conditions for density-functional based tight-binding, and using…

Materials Science · Physics 2009-11-13 Sami Malola , Hannu Häkkinen , Pekka Koskinen

We investigate the effect of lattice disorder and local correlation effects in finite and periodic silicene structures caused by carbon doping using first-principles calculations. For both finite and periodic silicene structures, the…

Proteins are minimally frustrated polymers. However, for realistic protein models non-native interactions must be taken into account. In this paper we analyze the effect of non-native interactions on the folding rate and on the folding free…

Biomolecules · Quantitative Biology 2007-05-23 C. Clementi , S. S. Plotkin

Density functional methods have been used to calculate the electronic properties of aligned smalldiameter single-walled carbon nanotubes under hydrostatic pressures. Abrupt pressure induced semiconductor-metal and metal-semiconductor…

Materials Science · Physics 2008-08-27 Sumit Saxena , Trevor A. Tyson

Experimental investigations of the biosynthesis of a number of proteins have pointed out that part of the native structure can be acquired already during translation. We carried out a comprehensive statistical analysis of some average…

Biomolecules · Quantitative Biology 2007-05-23 Alessandro Laio , Cristian Micheletti

Although wettability is a macroscopic manifestation of molecular-level forces, such as van der Waals (vdW) forces, the impact of nanoconfinement on material properties in reduced film thickness remains unexplored in predicting film…

Soft Condensed Matter · Physics 2025-06-05 Tara , Huang , Evon S. Petek , Reika Katsumata

Grate and co-workers at Pacific Northwest National Laboratory recently developed high information content triazine-based sequence-defined polymers that are robust by not having hydrolyzable bonds and can encode structure and functionality…

Chemical Physics · Physics 2019-07-31 Surl-Hee Ahn , Jay W. Grate , Eric F. Darve

The high rates of multi-parton interactions at the LHC can provide a unique opportunity to study the multi-parton structure of the hadron. To this purpose high energy collisions of protons with nuclei are particularly suitable. The rates of…

High Energy Physics - Phenomenology · Physics 2013-05-30 Daniele Treleani , Giorgio Calucci

The conformations available to polypeptides are determined by the interatomic forces acting on the peptide units, whereby backbone torsion angles are restricted as described by the Ramachandran plot. Although typical proteins are composed…

Biomolecules · Quantitative Biology 2013-02-11 Anil Korkut , Wayne A Hendrickson

The protein-protein interactions (PPIs) are crucial for understanding the majority of cellular processes. PPIs play important role in gene transcription regulation, cellular signaling, molecular basis of immune response and more. Moreover,…

Biomolecules · Quantitative Biology 2016-05-31 Maciej Pawel Ciemny , Mateusz Kurcinski , Andrzej Kolinski , Sebastian Kmiecik

We have examined the electronic structure evolution in transition metal dichalcogenides MX$_2$, where M=Mo,W and X=S,Se and Te. These are generally referred to as van der Waals heterostructures on the one hand, yet one has band gap changes…

Mesoscale and Nanoscale Physics · Physics 2024-02-02 S. K. Pandey , Ruma Das , Priya Mahadevan

Protein folding, peptide aggregation and crystallization, as well as adsorption of molecules on soft or solid substrates have an essential feature in common: In all these processes, structure formation is guided by a collective, cooperative…

Statistical Mechanics · Physics 2009-02-12 Michael Bachmann , Wolfhard Janke

Physical mechanisms underlying the empirical correlation between relative contact order (CO) and folding rate among naturally-occurring small single-domain proteins are investigated by evaluating postulated interaction schemes for a set of…

Statistical Mechanics · Physics 2007-05-23 Huseyin Kaya , Hue Sun Chan

The coil-globule transition of hetero-polymer chains is studied here. By means of extensive Molecular Dynamics simulations, we show that the transition is directly linked to the complexity of the chain, which depends on the number of…

Soft Condensed Matter · Physics 2022-09-07 Fabrizio Tafuri , Andrea Maria Chiariello

Despite the potential paradigm breaking capability of microcavities to control chemical processes, the extent to which photonic devices change properties of molecular materials is still unclear, in part due to challenges in modeling hybrid…

Chemical Physics · Physics 2021-12-30 Raphael F. Ribeiro