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We successfully evolved a neural network controller that produces dynamic walking in a simulated bipedal robot with compliant actuators, a difficult control problem. The evolutionary evaluation uses a detailed software simulation of a…

Neural and Evolutionary Computing · Computer Science 2009-07-13 Michael E. Palmer , Daniel B. Miller

Human societies around the world interact with each other by developing and maintaining social norms, and it is critically important to understand how such norms emerge and change. In this work, we define an evolutionary game-theoretic…

Computers and Society · Computer Science 2017-04-18 Soham De , Dana S. Nau , Michele J. Gelfand

Gynandromorphs are creatures where at least two different body sections are a different sex. Bilateral gynandromorphs are half male and half female. Here we develop a theory of gynandromorph ontogeny based on developmental control networks.…

Molecular Networks · Quantitative Biology 2012-12-24 Eric Werner

In this work we develop a microscopic physical model of early evolution, where phenotype,organism life expectancy, is directly related to genotype, the stability of its proteins in their native conformations which can be determined exactly…

Biomolecules · Quantitative Biology 2015-05-13 Konstantin Zeldovich , Peiqiu Chen , Boris Shakhnovich , Eugene Shakhnovich

Continuous adaptation allows survival in an ever-changing world. Adjustments in the synaptic coupling strength between neurons are essential for this capability, setting us apart from simpler, hard-wired organisms. How these changes can be…

Neurons and Cognition · Quantitative Biology 2021-01-06 Jakob Jordan , Maximilian Schmidt , Walter Senn , Mihai A. Petrovici

Balance of excitation and inhibition is a fundamental feature of in vivo network activity and is important for its computations. However, its presence in the neocortex of higher mammals is not well established. We investigated the dynamics…

Understanding how decision making changes across the lifespan is a central challenge for neuroscience, yet research on cognitive aging has remained largely disconnected from the theoretical and computational advances that now shape modern…

Neurons and Cognition · Quantitative Biology 2026-03-04 Michael B. Ryan , Letizia Ye , Anne K. Churchland

Research shows that gene duplication followed by either repurposing or removal of duplicated genes is an important contributor to evolution of gene and protein interaction networks. We aim to identify which characteristics of a network can…

Molecular Networks · Quantitative Biology 2021-07-27 Peter Crawford-Kahrl , Robert R. Nerem , Bree Cummins , Tomas Gedeon

This paper focuses on the maximum speed at which biological evolution can occur. I derive inequalities that limit the rate of evolutionary processes driven by natural selection, mutations, or genetic drift. These \emph{rate limits} link the…

Populations and Evolution · Quantitative Biology 2024-06-17 Luis Pedro García-Pintos

Adaptive reasoning enables humans to flexibly adjust inference strategies when environmental rules or contexts change, yet its underlying neural dynamics remain unclear. This study investigated the neurophysiological mechanisms of adaptive…

Artificial Intelligence · Computer Science 2025-11-12 Jun-Young Kim , Young-Seok Kweon , Gi-Hwan Shin , Seong-Whan Lee

We use the Allen Gene Expression Atlas (AGEA) and the OMA ortholog dataset to investigate the evolution of mouse-brain neuroanatomy from the standpoint of the molecular evolution of brain-specific genes. For each such gene, using the…

Quantitative Methods · Quantitative Biology 2012-06-05 Swagatam Mukhopadhyay , Pascal Grange , Anirvan M. Sengupta , Partha P. Mitra

We create an artificial system of agents (attention-based neural networks) which selectively exchange messages with each-other in order to study the emergence of memetic evolution and how memetic evolutionary pressures interact with genetic…

Artificial Intelligence · Computer Science 2021-04-09 Nicholas Guttenberg , Marek Rosa

The distribution of species body size within taxonomic groups exhibits a heavy right-tail extending over many orders of magnitude, where most species are significantly larger than the smallest species. We provide a simple model of…

Populations and Evolution · Quantitative Biology 2009-01-05 Aaron Clauset , Douglas H. Erwin

We analyze evolutionary dynamics in a confluent, branching cellular population, such as in a growing duct, vasculature, or in a branching microbial colony. We focus on the coarse-grained features of the evolution and build a statistical…

Populations and Evolution · Quantitative Biology 2022-02-15 Adam S. Bryant , Maxim O. Lavrentovich

The human niche represents the intersection of biological, ecological, cultural, and technological processes that have co-evolved to shape human adaptation and societal complexity. This paper explores the human niche through the lens of…

Populations and Evolution · Quantitative Biology 2025-06-27 Marcus J. Hamilton

Preterm birth disrupts the typical trajectory of cortical neurodevelopment, increasing the risk of cognitive and behavioral difficulties. However, outcomes vary widely, posing a significant challenge for early prediction. To address this,…

Neurons and Cognition · Quantitative Biology 2025-09-19 Zhenshan Xie , Levente Baljer , M. Jorge Cardoso , Emma Robinson

It has been an open question in deep learning if fault-tolerant computation is possible: can arbitrarily reliable computation be achieved using only unreliable neurons? In the grid cells of the mammalian cortex, analog error correction…

Machine Learning · Computer Science 2025-03-26 Alexander Zlokapa , Andrew K. Tan , John M. Martyn , Ila R. Fiete , Max Tegmark , Isaac L. Chuang

The discovery of Paranthropus deyiremeda in 3.3-3.5 million year old fossil sites in Afar (Haile-Selassie, 2015), together with 30% of the gorilla genome showing lineage sorting between humans and chimpanzees (Scally, 2012), and a NUMT…

Populations and Evolution · Quantitative Biology 2018-08-22 Johan Nygren

In this work we propose a physical model of organismal evolution, where phenotype, organism life expectancy, is directly related to genotype i.e. the stability of its proteins which can be determined exactly in the model. Simulating the…

Populations and Evolution · Quantitative Biology 2007-05-23 Konstantin B. Zeldovich , Boris E. Shakhnovich , Eugene I. Shakhnovich

Humans interact with each other on a daily basis by developing and maintaining various social norms and it is critical to form a deeper understanding of how such norms develop, how they change, and how fast they change. In this work, we…

Populations and Evolution · Quantitative Biology 2018-07-03 Soham De , Dana S. Nau , Xinyue Pan , Michele J. Gelfand
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