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Related papers: XORRO: Rapid Paired-End Read Overlapper

200 papers

Next-generation sequencing technologies generate millions of short sequence reads, which are usually aligned to a reference genome. In many applications, the key information required for downstream analysis is the number of reads mapping to…

Genomics · Quantitative Biology 2016-07-26 Yang Liao , Gordon K Smyth , Wei Shi

With the rapid advancements of deep learning in recent years, hardware accelerators are continuously deployed in more and more safety-critical applications such as autonomous driving and robotics. While the accelerators are usually…

Hardware Architecture · Computer Science 2023-08-31 Zuodong Zhang , Renjie Wei , Meng Li , Yibo Lin , Runsheng Wang , Ru Huang

The growing demand for real-time data processing in applications such as neural networks and embedded control systems has spurred the search for faster, more efficient alternatives to traditional electronic systems. In response, we…

Computation of a signal's estimated covariance matrix is an important building block in signal processing, e.g., for spectral estimation. Each matrix element is a sum of products of elements in the input matrix taken over a sliding window.…

Data Structures and Algorithms · Computer Science 2013-03-12 Oded Green , Lior David , Ami Galperin , Yitzhak Birk

Recent advances in reasoning models have demonstrated significant improvements in accuracy by employing detailed and comprehensive reasoning processes. However, generating these lengthy reasoning sequences is computationally expensive and…

Computation and Language · Computer Science 2025-08-27 Yijiong Yu

Existing research on instruction following largely focuses on tasks with simple instructions and short responses. In this work, we explore multi-constraint instruction following for generating long-form text. We create Suri, a dataset with…

Computation and Language · Computer Science 2024-10-03 Chau Minh Pham , Simeng Sun , Mohit Iyyer

In the last decade, an impressive increase in software adaptions has led to a surge in log data production, making manual log analysis impractical and establishing the necessity for automated methods. Conversely, most automated analysis…

Software Engineering · Computer Science 2025-11-19 Shayan Hashemi , Mika Mäntylä

Motivation: Illumina Sequencing data can provide high coverage of a genome by relatively short (100 bp150 bp) reads at a low cost. Our goal is to produce trimmed and error-corrected reads to improve genome assemblies. Our error correction…

Genomics · Quantitative Biology 2013-07-15 Guillaume Marçais , James A. Yorke , Aleksey Zimin

The proliferation of high-throughput sequencing machines ensures rapid generation of up to billions of short nucleotide fragments in a short period of time. This massive amount of sequence data can quickly overwhelm today's storage and…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-11-13 Subho S. Banerjee , Mohamed El-Hadedy , Jong Bin Lim , Zbigniew T. Kalbarczyk , Deming Chen , Steve Lumetta , Ravishankar K. Iyer

Pairwise sequence alignment is one of the most computationally intensive kernels in genomic data analysis, accounting for more than 90% of the runtime for key bioinformatics applications. This method is particularly expensive for…

This paper presents a novel approach to network coding for distribution of large files. Instead of the usual approach of splitting packets into disjoint classes (also known as generations) we propose the use of overlapping classes. The…

Information Theory · Computer Science 2019-05-07 Danilo Silva , Weifei Zeng , Frank R. Kschischang

Speech processing systems currently do not support the vast majority of languages, in part due to the lack of data in low-resource languages. Cross-lingual transfer offers a compelling way to help bridge this digital divide by incorporating…

Audio and Speech Processing · Electrical Eng. & Systems 2021-11-03 Peter Wu , Jiatong Shi , Yifan Zhong , Shinji Watanabe , Alan W Black

Motivation: The pan-genome can be stored as elastic-degenerate (ED) string, a recently introduced compact representation of multiple overlapping sequences. However, a search over the ED string does not indicate which individuals (if any)…

Data Structures and Algorithms · Computer Science 2020-04-16 Aleksander Cisłak , Szymon Grabowski

Arikan has shown that systematic polar codes (SPC) outperform nonsystematic polar codes (NSPC). However, the performance gain comes at the price of elevated encoding complexity, i.e., compared to NSPC, the available encoding methods for SPC…

Information Theory · Computer Science 2016-04-28 Guo Tai Chen , Zhaoyang Zhang , Caijun Zhong , Liang Zhang

Quad-level cell (QLC) flash offers significant benefits in cost and capacity, but its limited reliability leads to frequent read retries, which severely degrade read performance. A common strategy in high-density flash storage is to program…

Hardware Architecture · Computer Science 2025-08-28 Yanyun Wang , Dingcui Yu , Yina Lv , Yunpeng Song , Yumiao Zhao , Liang Shi

Parameter-efficient fine-tuning enables fast personalization of text-to-image diffusion models, but composing multiple custom concepts remains challenging due to representation interference. Existing modular methods either rely on expensive…

Machine Learning · Computer Science 2026-05-22 Javad Parsa , Enis Simsar , Amir Joudaki , Thomas Hofmann , André M. H. Teixeira

Read-optimized columnar databases use differential updates to handle writes by maintaining a separate write-optimized delta partition which is periodically merged with the read-optimized and compressed main partition. This merge process…

To obtain a better understanding of the trade-offs between various objectives, Bi-Objective Integer Programming (BOIP) algorithms calculate the set of all non-dominated vectors and present these as the solution to a BOIP problem.…

Optimization and Control · Mathematics 2019-09-10 William Pettersson , Melih Ozlen

VLM-based OCR models have become the de facto choice for document parsing, as they can accurately extract page-level elements (e.g., paragraphs within individual pages) together with their bounding boxes and textual content. However,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Bangrui Xu , Ziyang Miao , Xuanhe Zhou , Yiming Lin , Zirui Tang , Xiaomeng Zhao , Fan Wu , Cheng Tan , Fan Wu , Bin Wang , Conghui He

Computer Emergency Response Teams (CERTs) face increasing challenges processing the growing volume of security-related information. Daily manual analysis of threat reports, security advisories, and vulnerability announcements leads to…

Cryptography and Security · Computer Science 2025-02-07 Philipp Kuehn , Markus Bayer , Tobias Frey , Moritz Kerk , Christian Reuter