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The work is devoted to the analysis of cell population dynamics where cells make a choice between differentiation and apoptosis. This choice is based on the values of intracellular proteins whose concentrations are described by a system of…

Cell Behavior · Quantitative Biology 2016-03-30 Malay Banerjee , Vitaly Volpert

This paper develops a point-mutation model describing the evolutionary dynamics of a population of adult stem cells. Such a model may prove useful for quantitative studies of tissue aging and the emergence of cancer. We consider two modes…

Tissues and Organs · Quantitative Biology 2009-11-10 Emmanuel Tannenbaum , James L. Sherley , Eugene I. Shakhnovich

`Bursting', defined as periods of high frequency firing of a neuron separated by periods of quiescence, has been observed in various neuronal systems, both \textit{in vitro} and \textit{in vivo}. It has been associated with a range of…

Neurons and Cognition · Quantitative Biology 2018-06-20 E. Cotterill , S. J. Eglen

Gamma ray burst (GRB) time series is a non-stationary time series with all its statistical properties varying with time. Considering that each GRB is a different manifestation of the same stochastic process we studied the time dependent as…

High Energy Astrophysical Phenomena · Physics 2015-06-03 Nilay Bhatt , Subir Bhattacharyya

Minimally entangled typical thermal states (METTS) are a construction that allows one to to solve for the imaginary time evolution of quantum many body systems. By using wave functions that are weakly entangled, one can take advantage of…

Strongly Correlated Electrons · Physics 2022-04-27 Douglas Hendry , Hongwei Chen , Adrian Feiguin

Anisotropic barostats are employed to carry out Molecular Dynamics simulations where the volume is allowed to fluctuate with no constraints on the shape of the simulation cell. Most of these algorithms are based on second-order differential…

Chemical Physics · Physics 2021-11-15 Vittorio Del Tatto

Beams made from thin-walled elements, whilst very efficient in terms of the structural strength and stiffness to weight ratios, can be susceptible to highly complex instability phenomena. A nonlinear analytical formulation based on…

Pattern Formation and Solitons · Physics 2015-03-19 M. Ahmer Wadee , Leroy Gardner

Isologous diversification theory for cell differentiation is proposed, based on simulations of interacting cells with biochemical networks and cell division process following consumption of some chemicals. According to the simulations of…

adap-org · Physics 2008-02-03 Kunihiko Kaneko , Tetsuya Yomo

Clustering of molecules on biological membranes is a widely observed phenomenon. In some cases, such as the clustering of Ras proteins on the membranes of mammalian cells, proper cell signaling is critically dependent on the maintenance of…

Molecular Networks · Quantitative Biology 2019-08-28 Martijn Wehrens , Pieter Rein ten Wolde , Andrew Mugler

Multitype branching processes (MTBP) model branching structures, where the nodes of the resulting tree are objects of different types. One field of application of such models in biology is in studies of cell proliferation. A sampling scheme…

Computation · Statistics 2012-06-19 Nina Daskalova

Driven or active suspensions can display fascinating collective behavior, where coherent motions or structures arise on a scale much larger than that of the constituent particles. Here, we report experiments and numerical simulations…

In tensor networks, a geometric operation of pushing a bond cut surface toward a minimal surface corresponds to entanglement distillation. Cutting bonds defines a reduced transition matrix on the bond cut surface and the associated quantum…

High Energy Physics - Theory · Physics 2022-10-17 Takato Mori , Hidetaka Manabe , Hiroaki Matsueda

Consider a branching system with particles moving according to an Ornstein-Uhlenbeck process with drift $\mu>0$ and branching according to a law in the domain of attraction of the $(1+\beta)$-stable distribution. The mean of the branching…

Probability · Mathematics 2018-03-23 Rafał Marks , Piotr Miłoś

Distributed Bragg reflectors (DBRs) can be fabricated by electrochemically etching nitride epitaxial structures consisting of alternating layers of highly n-type doped and non-intentionally doped (NID) GaN. Threading dislocations (TDs) can…

While analyzing mobile systems we often approximate the actual coverage surface and assume an ideal cell shape. In a multi-cellular network, because of its tessellating nature, a hexagon is more preferred than a circular geometry. Despite…

Information Theory · Computer Science 2013-06-04 Mouhamed Abdulla , Yousef R. Shayan

We introduce and theoretically investigate a minimal particle-based model for a new class of active matter where particles exhibit directional, volume-conserving division in confinement while interacting sterically, mimicking cells in early…

Soft Condensed Matter · Physics 2024-10-01 Samantha R. Lish , Lukas Hupe , Ramin Golestanian , Philip Bittihn

The processes, resulting in the transcription of RNA, are intrinsically noisy. It was observed experimentally that the synthesis of mRNA molecules is driven by short, burst-like, events. An accurate prediction of the protein level often…

Populations and Evolution · Quantitative Biology 2009-10-14 Vlad Elgart

Transcription of genes is the focus of most forms of regulation of gene expression. Even though careful biochemical experimentation has revealed the molecular mechanisms of transcription initiation for a number of different promoters in…

Molecular Networks · Quantitative Biology 2018-10-17 Sandeep Choubey , Jane Kondev , Alvaro Sanchez

Cooperative behaviors arising from bacterial cell-to-cell communication can be modeled by reaction-diffusion equations having only a single diffusible component. This paper presents the following three contributions for the systematic…

Systems and Control · Computer Science 2016-11-15 Hiroki Miyazako , Yutaka Hori , Shinji Hara

Evolutionary branching is analysed in a stochastic, individual-based population model under mutation and selection. In such models, the common assumption is that individual reproduction and life career are characterised by values of a…

Populations and Evolution · Quantitative Biology 2025-10-01 S. Sagitov , B. Mehlig , P. Jagers , V. Vatutin