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Many causal systems such as biological processes in cells can only be observed indirectly via measurements, such as gene expression. Causal representation learning -- the task of correctly mapping low-level observations to latent causal…

Machine Learning · Computer Science 2025-10-31 Elliot Layne , Jason Hartford , Sébastien Lachapelle , Mathieu Blanchette , Dhanya Sridhar

Stochastic dynamics of several systems can be modeled via piecewise deterministic time evolution of the state, interspersed by random discrete events. Within this general class of systems, we consider time-triggered stochastic hybrid…

Systems and Control · Computer Science 2018-04-27 Mohammad Soltani , Abhyudai Singh

Investigations of natural variation among cells within a population are essential for understanding the stochastic nature of tissue cell deformation under applied load. In the existing literature, the population variation of single-cell…

Cell Behavior · Quantitative Biology 2011-07-14 John M. Maloney , Krystyn J. Van Vliet

The homeostasis of epithelial tissue relies on a balance between the self-renewal of stem cell populations, cellular differentiation, and loss. Although this balance needs to be tightly regulated to avoid pathologies, such as tumor growth,…

Biological Physics · Physics 2024-04-10 Johannes C. Krämer , Edouard Hannezo , Gerhard Gompper , Jens Elgeti

Spatial interaction between two or more classes or species has important implications in various fields and causes multivariate patterns such as segregation or association. Segregation occurs when members of a class or species are more…

Methodology · Statistics 2009-02-09 Elvan Ceyhan

Gene expression is inherently a noisy process which manifests as cell-to-cell variability in time evolution of proteins. Consequently, events that trigger at critical threshold levels of regulatory proteins exhibit stochasticity in their…

Subcellular Processes · Quantitative Biology 2016-09-26 Khem Raj Ghusinga , Abhyudai Singh

Cells of the human body have nearly identical genome but exhibit very different phenotypes that allow them to carry out specific functions and react to changes in their surrounding environment. This division of labour is achieved by…

Cell Behavior · Quantitative Biology 2021-11-24 Hanan Dreiwi , Flavia Feliciangeli , Mario Castro , Grant Lythe , Carmen Molina-París , Martín López-García

Randomized experiments ensure robust causal inference that are critical to effective learning analytics research and practice. However, traditional randomized experiments, like A/B tests, are limiting in large scale digital learning…

Applications · Statistics 2019-02-04 Timothy NeCamp , Josh Gardner , Christopher Brooks

Diffusion processes with branching play an important role in statistical dynamics. They are a common approach to the computing of quantum mechanical groundstates, and serve as models for population dynamics and as physical pictures for…

Condensed Matter · Physics 2008-02-03 Thomas Fricke

Cellular differentiation in a developping organism is studied via a discrete bistable reaction-diffusion model. A system of undifferentiated cells is allowed to receive an inductive signal emenating from its environment. Depending on the…

Pattern Formation and Solitons · Physics 2009-11-10 Gabor Fath , Zbigniew Domanski

We demonstrate how concepts of statistical mechanics of interacting particles can have important implications in the choice of interaction potentials to model qualitative properties of cell aggregates in theoretical biology. We illustrate…

Cell Behavior · Quantitative Biology 2017-06-29 J. A. Carrillo , A. Colombi , M. Scianna

Entanglement distillation, an essential quantum information processing task, refers to the conversion from multiple copies of noisy entangled states to a smaller number of highly entangled states. In this work, we study the non-asymptotic…

Quantum Physics · Physics 2019-10-03 Kun Fang , Xin Wang , Marco Tomamichel , Runyao Duan

The cell cortex, a thin film of active material assembled below the cell membrane, plays a key role in cellular symmetry breaking processes such as cell polarity establishment and cell division. Here, we present a minimal model of the…

Biological Physics · Physics 2019-09-30 Alexander Mietke , V. Jemseena , K. Vijay Kumar , Ivo F. Sbalzarini , Frank Jülicher

We study a continuous time Mutually Catalytic Branching model on the $\mathbb{Z}^{d}$. The model describes the behavior of two different populations of particles, performing random walk on the lattice in the presence of branching, that is,…

Probability · Mathematics 2026-01-14 Alexandra Jamchi Fugenfirov , Leonid Mytnik

An intrinsic branching structure within the transient random walk on a strip in a random environment is revealed. As applications, which enables us to express the hitting time explicitly, and specifies the density of the absolutely…

Probability · Mathematics 2012-04-06 Wenming Hong , Meijuan Zhang

Stochastic processes can model many emerging phenomena on networks, like the spread of computer viruses, rumors, or infectious diseases. Understanding the dynamics of such stochastic spreading processes is therefore of fundamental interest.…

Social and Information Networks · Computer Science 2019-01-07 Gerrit Großmann , Verena Wolf

Small systems in a thermodynamic medium --- like colloids in a suspension or the molecular machinery in living cells --- are strongly affected by the thermal fluctuations of their environment. Physicists model such systems by means of…

Statistical Mechanics · Physics 2014-10-16 Bernhard Altaner

In multicellular organisms, epithelial cells form layers separating compartments responsible for different physiological functions. At the early stage of epithelial layer formation, each cell of an aggregate defines an inner and an outer…

Cell Behavior · Quantitative Biology 2010-02-09 A. Veglio , A. Gamba , M. Nicodemi , F. Bussolino , G. Serini

The analysis of the BATSE's count distribution within cosmological models suffers from observational uncertainties due to the variability of the bursts' spectra: when BATSE observes bursts from different redshifts at a fixed energy band it…

Astrophysics · Physics 2009-10-28 Ehud Cohen , Tsvi Piran

We describe Structured Random Binding (SRB), a minimal model of protein-protein interactions rooted in the statistical physics of disordered systems. In this model, nonspecific binding is a generic consequence of the interaction between…

Statistical Mechanics · Physics 2025-03-27 Ling-Nan Zou