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We investigate a stochastic process where a rectangle breaks into smaller rectangles through a series of horizontal and vertical fragmentation events. We focus on the case where both the vertical size and the horizontal size of a rectangle…

Statistical Mechanics · Physics 2019-09-17 E. Ben-Naim , P. L. Krapivsky

We investigate several important issues regarding the Random Batch Method (RBM) for second order interacting particle systems. We first show the uniform-in-time strong convergence for second order systems under suitable contraction…

Numerical Analysis · Mathematics 2020-12-02 Shi Jin , Lei Li , Yiqun Sun

Gene expression in individual cells is highly variable and sporadic, often resulting in the synthesis of mRNAs and proteins in bursts. Bursting in gene expression is known to impact cell-fate in diverse systems ranging from latency in HIV-1…

Molecular Networks · Quantitative Biology 2016-02-17 Niraj Kumar , Abhyudai Singh , Rahul V. Kulkarni

For cell-division processes in a window, Cowan introduced four selection rules and two division rules each of which stands for one cell-division model. One of these is the area-weighted in-cell model. In this model, each cell is selected…

Probability · Mathematics 2012-04-16 Eike Biehler

Cell fate determination, the process through which cells commit to differentiated states is commonly mediated by gene regulatory motifs with mutually exclusive expression states. The classical deterministic picture for cell fate…

Molecular Networks · Quantitative Biology 2019-10-09 Manuel Pájaro , Irene Otero-Muras , Carlos Vázquez , Antonio A. Alonso

The first-passage time (FPT), i.e., the moment when a stochastic process reaches a given threshold value for the first time, is a fundamental mathematical concept with immediate applications. In particular, it quantifies the statistics of…

Subcellular Processes · Quantitative Biology 2018-12-05 Denis S. Grebenkov , Ralf Metzler , Gleb Oshanin

Dataset distillation extracts a small set of synthetic training samples from a large dataset with the goal of achieving competitive performance on test data when trained on this sample. In this work, we tackle dataset distillation at its…

Machine Learning · Computer Science 2023-11-14 Yunzhen Feng , Ramakrishna Vedantam , Julia Kempe

Stochasticity is both exploited and controlled by cells. Although the intrinsic stochasticity inherent in biochemistry is relatively well understood, cellular variation, or 'noise', is predominantly generated by interactions of the system…

Molecular Networks · Quantitative Biology 2008-09-18 Vahid Shahrezaei , Julien F Ollivier , Peter S Swain

Tensor ring (TR) decomposition is a simple but effective tensor network for analyzing and interpreting latent patterns of tensors. In this work, we propose a doubly randomized optimization framework for computing TR decomposition. It can be…

Numerical Analysis · Mathematics 2023-03-30 Yajie Yu , Hanyu Li , Jingchun Zhou

The notion of stability can be generalised to point processes by defining the scaling operation in a randomised way: scaling a configuration by $t$ corresponds to letting such a configuration evolve according to a Markov branching particle…

Probability · Mathematics 2015-10-28 Giacomo Zanella , Sergei Zuyev

Space partitioning methods such as random forests and the Mondrian process are powerful machine learning methods for multi-dimensional and relational data, and are based on recursively cutting a domain. The flexibility of these methods is…

Machine Learning · Statistics 2019-12-03 Shufei Ge , Shijia Wang , Yee Whye Teh , Liangliang Wang , Lloyd T. Elliott

Experimental studies of cell motility in culture have shown that under adequate conditions these living organisms possess the ability to organize themselves into complex structures. Such structures may exhibit a synergy that greatly…

Statistical Mechanics · Physics 2021-10-27 G. Nakamura , M. Badoual , E. Fabiani , C. Deroulers

We describe the evolution of the quantity of parasites in a population of cells which divide in continuous-time. The quantity of parasites in a cell follows a Feller diffusion, which is splitted randomly between the two daughter cells when…

Populations and Evolution · Quantitative Biology 2011-01-18 Vincent Bansaye , Viet Chi Tran

Chlamydiae are bacteria with an interesting unusual developmental cycle. A single bacterium in its infectious form (elementary body, EB) enters the host cell, where it converts into its dividing form (reticulate body, RB), and divides by…

Populations and Evolution · Quantitative Biology 2023-06-06 Péter Kevei , Máté Szalai

We begin by reviewing some probabilistic results about the Dirichlet Process and its close relatives, focussing on their implications for statistical modelling and analysis. We then introduce a class of simple mixture models in which…

Methodology · Statistics 2010-03-23 Peter J. Green

We introduce a family of branch merging operations on continuum trees and show that Ford CRTs are distributionally invariant. This operation is new even in the special case of the Brownian CRT, which we explore in more detail. The…

Probability · Mathematics 2016-06-23 Franz Rembart

Branching processes are used to model diverse social and physical scenarios, from extinction of family names to nuclear fission. However, for a better description of natural phenomena, such as viral epidemics in cellular tissues, animal…

We consider a binary branching process structured by a stochastic trait that evolves according to a diffusion process that triggers the branching events, in the spirit of Kimmel's model of cell division with parasite infection. Based on the…

Statistics Theory · Mathematics 2019-02-27 Marc Hoffmann , Aline Marguet

T cell receptor signaling must operate reliably under tight time constraints. While assuming quite different mechanisms, two prominent models of T cell receptor activation, kinetic segregation and kinetic proofreading, both introduce a…

Quantitative Methods · Quantitative Biology 2024-12-10 Thorsten Prüstel , Martin Meier-Schellersheim

A dynamic model for cell differentiation is studied, where cells with internal chemical reaction dynamics interact with each other and replicate. It leads to spontaneous differentiation of cells and determination, as is discussed in the…

adap-org · Physics 2007-05-23 Chikara Furusawa , Kunihiko Kaneko