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Most machine learning (ML) models are developed for prediction only; offering no option for causal interpretation of their predictions or parameters/properties. This can hamper the health systems' ability to employ ML models in clinical…

The work we describe here is a part of a research program of developing foundations of declarative solving of search problems. We consider the model expansion task as the task representing the essence of search problems where we are given…

Logic in Computer Science · Computer Science 2011-09-06 Shahab Tasharrofi , Xiongnan , Wu , Eugenia Ternovska

The efficacy of robust optimization spans a variety of settings with uncertainties bounded in predetermined sets. In many applications, uncertainties are affected by decisions and cannot be modeled with current frameworks. This paper takes…

Optimization and Control · Mathematics 2018-03-29 Omid Nohadani , Kartikey Sharma

The aim of behaviour change is to help people to change aspects of their behaviour for the better (e.g., to decrease calorie intake, to drink in moderation, to take more exercise, to complete a course of antibiotics once started, etc.). In…

Artificial Intelligence · Computer Science 2018-02-28 Lisa Chalaguine , Emmanuel Hadoux , Fiona Hamilton , Andrew Hayward , Anthony Hunter , Sylwia Polberg , Henry W. W. Potts

We consider problems of making sequences of decisions to accomplish tasks, interacting via the medium of language. These problems are often tackled with reinforcement learning approaches. We find that these models do not generalize well…

Computation and Language · Computer Science 2020-10-07 Xusen Yin , Ralph Weischedel , Jonathan May

The aim of this paper is to evaluate whether large language models trained on multi-choice question data can be used to discriminate between medical subjects. This is an important and challenging task for automatic question answering. To…

Computation and Language · Computer Science 2024-03-22 Víctor Ponce-López

There is a recent proliferation of research on the integration of machine learning and optimization. One expansive area within this research stream is predictive-model embedded optimization, which proposes the use of pre-trained predictive…

Machine Learning · Computer Science 2022-10-20 Chenbo Shi , Mohsen Emadikhiav , Leonardo Lozano , David Bergman

Conventional inverse optimization inputs a solution and finds the parameters of an optimization model that render a given solution optimal. The literature mostly focuses on inferring the objective function in linear problems when accepted…

Optimization and Control · Mathematics 2024-10-10 Houra Mahmoudzadeh , Kimia Ghobadi

Clinical decision-making in oncology requires predicting dynamic disease evolution, a task current static AI predictors cannot perform. While world models (WMs) offer a paradigm for generative prediction, existing medical applications…

Machine Learning · Computer Science 2026-03-30 Tianxingjian Ding , Yuanhao Zou , Chen Chen , Mubarak Shah , Yu Tian

This paper establishes fundamental results for statistical inference of diagnostic classification models (DCM). The results are developed at a high level of generality, applicable to essentially all diagnostic classification models. In…

Statistics Theory · Mathematics 2025-01-08 Guanhua Fang , Jingchen Liu , Zhiliang Ying

A dynamic treatment regime is a sequence of decision rules in which each decision rule recommends treatment based on features of patient medical history such as past treatments and outcomes. Existing methods for estimating optimal dynamic…

Methodology · Statistics 2015-05-22 Kristin A. Linn , Eric B. Laber , Leonard A. Stefanski

The premise of the Multi-disciplinary Conference on Reinforcement Learning and Decision Making is that multiple disciplines share an interest in goal-directed decision making over time. The idea of this paper is to sharpen and deepen this…

Artificial Intelligence · Computer Science 2022-06-07 Richard S. Sutton

In clinical settings, we often face the challenge of building prediction models based on small observational data sets. For example, such a data set might be from a medical center in a multi-center study. Differences between centers might…

Any probabilistic model of a problem is based on assumptions which, if violated, invalidate the model. Users of probability based decision aids need to be alerted when cases arise that are not covered by the aid's model. Diagnosis of model…

Artificial Intelligence · Computer Science 2013-03-26 Kathryn Blackmond Laskey

The automatic generation of decision trees based on off-line reasoning on models of a domain is a reasonable compromise between the advantages of using a model-based approach in technical domains and the constraints imposed by embedded…

Artificial Intelligence · Computer Science 2011-06-28 L. Console , C. Picardi , D. Theseider Duprè

Large Language Models (LLMs) have demonstrated surprising performance across various natural language processing tasks. Recently, medical LLMs enhanced with domain-specific knowledge have exhibited excellent capabilities in medical…

Computation and Language · Computer Science 2024-09-24 Jinqiang Wang , Huansheng Ning , Yi Peng , Qikai Wei , Daniel Tesfai , Wenwei Mao , Tao Zhu , Runhe Huang

Precision medicine is accelerating rapidly in the field of health research. This includes fitting predictive models for individual patients based on patient similarity in an attempt to improve model performance. We propose an algorithm…

Methodology · Statistics 2025-02-07 Tatiana Krikella , Joel A. Dubin

Model selection methods are used in different scientific contexts to represent a characteristic data set in terms of a reduced number of parameters. Apparently, these methods have not found their way into the literature on multibody systems…

Robotics · Computer Science 2017-05-30 Javier Ros , Xabier Iriarte , Aitor Plaza , Vicente Mata

Matrix completion estimators are employed in causal panel data models to regulate the rank of the underlying factor model using nuclear norm minimization. This convex optimization problem enables concurrent regularization of a potentially…

Econometrics · Economics 2024-02-05 Sandro Heiniger

ksmt is a CDCL-style calculus for solving non-linear constraints over real numbers involving polynomials and transcendental functions. In this paper we investigate properties of the ksmt calculus and show that it is a $\delta$-complete…

Logic in Computer Science · Computer Science 2021-04-28 Franz Brauße , Konstantin Korovin , Margarita V. Korovina , Norbert Th. Müller
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