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An important factor in the practical implementation of optimization models is the acceptance by the intended users. This is influenced among other factors by the interpretability of the solution process. Decision rules that meet this…

Machine Learning · Computer Science 2024-12-03 Marc Goerigk , Michael Hartisch , Sebastian Merten

The goal of cancer immunotherapy is to boost a patient's immune response to a tumor. Yet, the design of an effective immunotherapy is complicated by various factors, including a potentially immunosuppressive tumor microenvironment,…

Tissues and Organs · Quantitative Biology 2017-06-29 Anna Konstorum , Anthony T. Vella , Adam J. Adler , Reinhard Laubenbacher

ChatGPT explores a strategic blueprint of question answering (QA) in delivering medical diagnosis, treatment recommendations, and other healthcare support. This is achieved through the increasing incorporation of medical domain data via…

Computation and Language · Computer Science 2024-01-23 Qing Li , Lei Li , Yu Li

With time, machine learning models have increased in their scope, functionality and size. Consequently, the increased functionality and size of such models requires high-end hardware to both train and provide inference after the fact. This…

Machine Learning · Computer Science 2021-09-07 Arhum Ishtiaq , Sara Mahmood , Maheen Anees , Neha Mumtaz

This survey is focused on certain sequential decision-making problems that involve optimizing over probability functions. We discuss the relevance of these problems for learning and control. The survey is organized around a framework that…

Optimization and Control · Mathematics 2023-01-13 Emiland Garrabe , Giovanni Russo

Constraint problems can be trivially solved in parallel by exploring different branches of the search tree concurrently. Previous approaches have focused on implementing this functionality in the solver, more or less transparently to the…

Artificial Intelligence · Computer Science 2010-08-26 Lars Kotthoff , Neil C. A. Moore

Mathematical models are increasing adopted for setting targets for disease prevention and control. As model-informed policies are implemented, however, the inaccuracies of some forecasts become apparent, for example overprediction of…

For optimization models to be used in practice, it is crucial that users trust the results. A key factor in this aspect is the interpretability of the solution process. A previous framework for inherently interpretable optimization models…

Optimization and Control · Mathematics 2026-02-13 Marc Goerigk , Michael Hartisch , Sebastian Merten , Kartikey Sharma

Risk adjustment has become an increasingly important tool in healthcare. It has been extensively applied to payment adjustment for health plans to reflect the expected cost of providing coverage for members. Risk adjustment models are…

Machine Learning · Computer Science 2019-07-16 Qiu-Yue Zhong , Andrew H. Fairless , Jasmine M. McCammon , Farbod Rahmanian

This dissertation explores the topics of parameter estimation and model reduction in the context of quantum filtering. Chapters 2 and 3 provide a review of classical and quantum probability theory, stochastic calculus and filtering. Chapter…

Quantum Physics · Physics 2009-08-11 Bradley A. Chase

In this paper, we present a unified framework for decision making under uncertainty. Our framework is based on the composite of two risk measures, where the inner risk measure accounts for the risk of decision given the exact distribution…

Optimization and Control · Mathematics 2015-01-07 Pengyu Qian , Zizhuo Wang , Zaiwen Wen

We propose a novel approach for decision making problems leveraging the generalization capabilities of large language models (LLMs). Traditional methods such as expert systems, planning algorithms, and reinforcement learning often exhibit…

Computation and Language · Computer Science 2024-08-13 Yu Zhang , Haoxiang Liu , Feijun Jiang , Weihua Luo , Kaifu Zhang

In recent years, transformer-based language representation models (LRMs) have achieved state-of-the-art results on difficult natural language understanding problems, such as question answering and text summarization. As these models are…

Computation and Language · Computer Science 2022-10-17 Zhisheng Tang , Mayank Kejriwal

Compartmental epidemic models have been widely used for predicting the course of epidemics, from estimating the basic reproduction number to guiding intervention policies. Studies commonly acknowledge these models' assumptions but less…

Populations and Evolution · Quantitative Biology 2022-11-23 Alexander F. Siegenfeld , Pratyush K. Kollepara , Yaneer Bar-Yam

[Spreadsheet] Models are invaluable tools for strategic planning. Models help key decision makers develop a shared conceptual understanding of complex decisions, identify sensitivity factors and test management scenarios. Different…

Human-Computer Interaction · Computer Science 2024-12-31 Paula Jennings

We propose a new paradigm for Belief Change in which the new information is represented as sets of models, while the agent's body of knowledge is represented as a finite set of formulae, that is, a finite base. The focus on finiteness is…

Logic in Computer Science · Computer Science 2023-09-13 Ricardo Guimarães , Ana Ozaki , Jandson S. Ribeiro

Large Language Models (LLMs) have made significant progress in various fields. However, challenges remain in Multi-Disciplinary Team (MDT) medical consultations. Current research enhances reasoning through role assignment, task…

Artificial Intelligence · Computer Science 2025-03-19 Kai Chen , Xinfeng Li , Tianpei Yang , Hewei Wang , Wei Dong , Yang Gao

We describe an augmented intelligence system for simplifying and enhancing the modeling experience for operations research. Using this system, the user receives a suggested formulation of an optimization problem based on its description. To…

Computation and Language · Computer Science 2022-10-13 Rindranirina Ramamonjison , Haley Li , Timothy T. Yu , Shiqi He , Vishnu Rengan , Amin Banitalebi-Dehkordi , Zirui Zhou , Yong Zhang

We describe a variational approximation method for efficient inference in large-scale probabilistic models. Variational methods are deterministic procedures that provide approximations to marginal and conditional probabilities of interest.…

Artificial Intelligence · Computer Science 2011-05-30 T. S. Jaakkola , M. I. Jordan

Large language models (LLMs) have emerged as powerful tools with transformative potential across numerous domains, including healthcare and medicine. In the medical domain, LLMs hold promise for tasks ranging from clinical decision support…

Computation and Language · Computer Science 2024-05-14 Xiaolan Chen , Jiayang Xiang , Shanfu Lu , Yexin Liu , Mingguang He , Danli Shi