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Dengue fever is a vector-borne disease mostly endemic to tropical and subtropical countries that affect millions every year and is considered a significant burden for public health. Its geographic distribution makes it highly sensitive to…

Computers and Society · Computer Science 2022-04-05 Luis A. Barboza , Shu-Wei Chou , Paola Vásquez , Yury E. García , Juan G. Calvo , Hugo C. Hidalgo , Fabio Sanchez

Epidemiological models may give some basic guidelines for public health practitioners, allowing to analyze issues that can influence the strategies to prevent and fight a disease. To be used in decision-making, however, a mathematical model…

Populations and Evolution · Quantitative Biology 2013-08-15 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres

This paper is about numerical control of HIV propagation. The contribution of the paper is threefold: first, a novel model of HIV propagation is proposed; second, the methods from numerical optimal control are successfully applied to the…

Systems and Control · Computer Science 2023-05-30 Dmitry Gromov , Ingo Bulla , Ethan O. Romero-Severson , Oana Silvia Serea

A two-patch mathematical model of Dengue virus type 2 (DENV-2) that accounts for vectors' vertical transmission and between patches human dispersal is introduced. Dispersal is modeled via a Lagrangian approach. A host-patch residence-times…

Populations and Evolution · Quantitative Biology 2016-01-26 Derdei Bichara , Susan A. Holechek , Jorge Velazquez-Castro , Anarina L. Murillo , Carlos Castillo-Chavez

Solving complex optimal control problems have confronted computational challenges for a long time. Recent advances in machine learning have provided us with new opportunities to address these challenges. This paper takes model predictive…

Optimization and Control · Mathematics 2022-07-21 Weinan E , Jiequn Han , Jihao Long

It is possible to model vector-borne infection using the classical Ross-Macdonald model. This attempt, however fails in several respects. First, using measured (or estimated) parameters, the model predicts a much greater number of cases…

We introduce a dengue model (SEIR) where the human individuals are treated on an individual basis (IBM) while the mosquito population, produced by an independent model, is treated by compartments (SEI). We study the spread of epidemics by…

Populations and Evolution · Quantitative Biology 2015-03-17 Marcelo J Otero , Daniel H Barmak , Claudio O Dorso , Hernán G Solari , Mario A Natiello

Predicting an infectious disease can help reduce its impact by advising public health interventions and personal preventive measures. Novel data streams, such as Internet and social media data, have recently been reported to benefit…

Efficient testing and vaccination protocols are critical aspects of epidemic management. To study the optimal allocation of limited testing and vaccination resources in a heterogeneous contact network of interacting susceptible, recovered,…

Populations and Evolution · Quantitative Biology 2026-05-12 Mingtao Xia , Lucas Böttcher , Tom Chou

Compartmental models have long served as important tools in mathematical epidemiology, with their usefulness highlighted by the recent COVID-19 pandemic. However, most of the classical models fail to account for certain features of this…

Dynamical Systems · Mathematics 2023-08-21 Monique Chyba , Taylor Klotz , Yuriy Mileyko , Corey Shanbrom

It is preliminarily known that Aedes mosquitoes are very close to humans and their dwellings, also give rises to a broad spectrum of diseases: dengue, yellow fever, chikungunya. In this paper, we explore a multi-age-class model for mosquito…

Optimization and Control · Mathematics 2017-12-04 Karunia Putra Wijaya , Thomas Goetz , Edy Soewono

Dengue fever is increasing in geographical range, spread by invasion of its vector mosquitoes. The trade in second-hand tires has been implicated as a factor in this process as they act as mobile reservoirs of mosquito eggs and larvae.…

Populations and Evolution · Quantitative Biology 2017-01-23 Emilene Pliego Pliego , Jorge Velázquez-Castro , Markus P. Eichhorn , Andrés Fraguela Collar

In the last two decades dengue cases increased significantly throughout the world. In several regions dengue re-emerged, particularly in Latin America, where dengue cases not only increased but also occurred more frequently. It is therefore…

Populations and Evolution · Quantitative Biology 2022-04-12 Javier Armando Gutierrez , Karina Laneri , Juan Pablo Aparicio , Gustavo Javier Sibona

In this paper, we study an age-structured model which has strong biological background about mosquito plasticity. Firstly, we prove the existence of solutions and the comparison principle for a generalized system. Then, we prove the…

Analysis of PDEs · Mathematics 2018-04-26 Lin Lin Li , Cláudia Pio Ferreira , Bedreddine Ainseba

We analyze a class of general nonlinear epidemic models with age and space structure, including a nonlocal infection term depending on age and space. After establishing the well-posedness of the state partial differential equation, we…

Optimization and Control · Mathematics 2025-03-11 Behzad Azmi , Nicolas Schlosser

Mosquitoes are responsible for the transmission of many diseases such as dengue fever, zika or chigungunya. One way to control the spread of these diseases is to use the sterile insect technique (SIT), which consists in a massive release of…

Analysis of PDEs · Mathematics 2021-11-17 Luís Almeida , Michel Duprez , Yannick Privat , Nicolas Vauchelet

In this paper we propose some mathematical models for the transmission of dengue using a system of reaction-diffusion equations. The mosquitoes are divided into infected, uninfected and aquatic subpopulations, while the humans, which are…

Analysis of PDEs · Mathematics 2018-11-21 Felipo Bacani , Stylianos Dimas , Igor Leite Freire , Norberto Anibal Maidana , Mariano Torrisi

Dengue is a vector borne disease transmitted to humans by {\it{Aedes Aegypti}} mosquitoes carrying Dengue virus of different serotypes. Primarily an urban epidemic, Dengue exhibits complex spatial and temporal dynamics, influenced by many…

Populations and Evolution · Quantitative Biology 2015-04-30 Murali Krishna Enduri , Shivakumar Jolad

Based on approximately 90,000 confirmed dengue cases reported in Recife - a major city in northeastern Brazil - between 2015 and 2024, we conducted a neighborhood-level spatial analysis. Socioeconomic and demographic indicators from the…

Applications · Statistics 2025-07-15 Marcílio Ferreira dos Santos

Dengue control in India is a challenging task due to complex healthcare settings. In yesteryears, an amplification of dengue infections in India posed the need for introspection of existing dengue control policies. Prior understanding of…

Populations and Evolution · Quantitative Biology 2021-06-29 Indrajit Ghosh , Pankaj Kumar Tiwari , Joydev Chattopadhyay