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Phylogenetic networks are increasingly used in evolutionary biology to represent the history of species that have undergone reticulate events such as horizontal gene transfer, hybrid speciation and recombination. One of the most fundamental…

Populations and Evolution · Quantitative Biology 2016-10-07 Philippe Gambette , Leo van Iersel , Steven Kelk , Fabio Pardi , Celine Scornavacca

Grey literature is essential to software engineering research as it captures practices and decisions that rarely appear in academic venues. However, collecting and assessing it at scale remains difficult because of their heterogeneous…

Recent transformer-based approaches demonstrate promising results on relational scientific information extraction. Existing datasets focus on high-level description of how research is carried out. Instead we focus on the subtleties of how…

Computation and Language · Computer Science 2021-09-23 Ian H. Magnusson , Scott E. Friedman

This paper presents the ReXCL tool, which automates the extraction and classification processes in requirements engineering, enhancing the software development life-cycle. The tool features two main modules: Extraction, which processes raw…

Software Engineering · Computer Science 2026-05-13 Paheli Bhattacharya , Manojit Chakraborty , Santhosh Kumar Arumugam , Rishabh Gupta

$\textbf{Motivation:}$ Hierarchical data structures are prevalent across several fields of research, as they represent an organised and efficient approach to study complex interconnected systems. Their significance is particularly evident…

Mathematical Software · Computer Science 2024-12-06 Giulio Benedetti , Ely Seraidarian , Theotime Pralas , Akewak Jeba , Tuomas Borman , Leo Lahti

The Tree of Life is the graphical structure that represents the evolutionary process from single-cell organisms at the origin of life to the vast biodiversity we see today. Reconstructing this tree from genomic sequences is challenging due…

Populations and Evolution · Quantitative Biology 2020-10-06 Claudia Solis-Lemus , Arrigo Coen , Cecile Ane

Typing methods are widely used in the surveillance of infectious diseases, outbreaks investigation and studies of the natural history of an infection. And their use is becoming standard, in particular with the introduction of High…

Data Structures and Algorithms · Computer Science 2020-06-16 Cátia Vaz , Marta Nascimento , João A. Carriço , Tatiana Rocher , Alexandre P. Francisco

Phylogenetic networks are rooted acyclic directed graphs in which the leaves are identified with members of a set X of species. The cluster of a vertex is the set of leaves that are descendants of the vertex. A network is "distinct-cluster"…

Combinatorics · Mathematics 2017-04-11 Stephen J. Willson

Causality extraction from natural language texts is a challenging open problem in artificial intelligence. Existing methods utilize patterns, constraints, and machine learning techniques to extract causality, heavily depending on domain…

Computation and Language · Computer Science 2020-11-10 Zhaoning Li , Qi Li , Xiaotian Zou , Jiangtao Ren

With ongoing developments and innovations in single-cell RNA sequencing methods, advancements in sequencing performance could empower significant discoveries as well as new emerging possibilities to address biological and medical…

Applications · Statistics 2019-12-19 Jiawei Long , Yu Xia

Biclustering is a data mining technique which searches for local patterns in numeric tabular data with main application in bioinformatics. This technique has shown promise in multiple areas, including development of biomarkers for cancer,…

Machine Learning · Computer Science 2021-05-05 Paweł Renc , Patryk Orzechowski , Aleksander Byrski , Jarosław Wąs , Jason H. Moore

In this work, we answer an open problem in the study of phylogenetic networks. Phylogenetic trees are rooted binary trees in which all edges are directed away from the root, whereas phylogenetic networks are rooted acyclic digraphs. For the…

Populations and Evolution · Quantitative Biology 2015-11-12 Andreas D. M. Gunawan , Bhaskar DasGupta , Louxin Zhang

A merge tree is a topological descriptor of a real-valued function. Merge trees are used in visualization and topological data analysis, either directly or as a means to another end: computing a 0-dimensional persistence diagram,…

Computational Geometry · Computer Science 2023-01-31 Arnur Nigmetov , Dmitriy Morozov

Background: With the rapid growth of massively parallel sequencing technologies, still more laboratories are utilizing sequenced DNA fragments for genomic analyses. Interpretation of sequencing data is, however, strongly dependent on…

Phylogenetics is a widely used concept in evolutionary biology. It is the reconstruction of evolutionary history by building trees that represent branching patterns and sequences. These trees represent shared history, and it is our…

Astrophysics of Galaxies · Physics 2018-08-22 P. Jofre , P. Das

Phylogenetic networks are necessary to represent the tree of life expanded by edges to represent events such as horizontal gene transfers, hybridizations or gene flow. Not all species follow the paradigm of vertical inheritance of their…

Populations and Evolution · Quantitative Biology 2016-02-15 Claudia Solís-Lemus , Cécile Ané

Single-cell RNA sequencing (scRNA-seq) enables researchers to analyze gene expression at single-cell level. One important task in scRNA-seq data analysis is unsupervised clustering, which helps identify distinct cell types, laying down the…

Genomics · Quantitative Biology 2023-12-29 Weikang Jiang , Jinxian Wang , Jihong Guan , Shuigeng Zhou

Interest in the inference of evolutionary networks relating species or populations has grown with the increasing recognition of the importance of hybridization, gene flow and admixture, and the availability of large-scale genomic data.…

Populations and Evolution · Quantitative Biology 2024-07-23 John A. Rhodes , Hector Banos , Jingcheng Xu , Cécile Ané

Comparisons of single-cell RNA sequencing (scRNA-seq) data across species can reveal links between cellular gene expression and the evolution of cell functions, features, and phenotypes. These comparisons invoke evolutionary histories, as…

Populations and Evolution · Quantitative Biology 2023-07-07 Samuel H. Church , Jasmine L. Mah , Casey W. Dunn

Synthetic biology brings together concepts and techniques from engineering and biology. In this field, computer-aided design (CAD) is necessary in order to bridge the gap between computational modeling and biological data. An application…

Molecular Networks · Quantitative Biology 2009-07-24 Deepak Chandran , Frank T. Bergmann , Herbert M. Sauro