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Related papers: Intervention-Based Stochastic Disease Eradication

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Traditional disease transmission models assume that the infectious period is exponentially distributed with a recovery rate fixed in time and across individuals. This assumption provides analytical and computational advantages, however it…

Populations and Evolution · Quantitative Biology 2024-01-30 Laura Di Domenico , Eugenio Valdano , Vittoria Colizza

Populations can evolve in order to adapt to external changes. The capacity to evolve and adapt makes successful treatment of infectious diseases and cancer difficult. Indeed, therapy resistance has quickly become a key challenge for global…

Populations and Evolution · Quantitative Biology 2015-06-22 Andrej Fischer , Ignacio Vazquez-Garcia , Ville Mustonen

We propose a framework for the description of the effects of vaccinations on the spreading of an epidemic disease. Different vaccines can be dosed, each providing different immunization times and immunization levels. Differences due to…

Analysis of PDEs · Mathematics 2024-07-23 Rinaldo M. Colombo , Mauro Garavello

In randomized controlled trials (RCTs) of infectious disease interventions, it is well recognized that unmeasured individual heterogeneity at baseline can induce selection bias over time, thereby complicating the interpretation of the…

Methodology · Statistics 2026-04-24 Hiroyasu Ando , A. James O'Malley , Akihiro Nishi

A class of stochastic vector-borne infectious disease models is derived and studied. The class type is determined by a general nonlinear incidence rate of the disease. The disease spreads in a highly random environment with variability from…

Populations and Evolution · Quantitative Biology 2020-05-05 Divine Wanduku

We show we can control an epidemic reaction-diffusion on a directed, and heterogeneous, network by redirecting the flows, thanks to the optimisation of well-designed loss functions, in particular the basic reproduction number of the model.…

Dynamical Systems · Mathematics 2022-02-07 Pierre-Yves Massé , Quentin Laborde , Maria Cherifa , Jules Olayé , Laurent Oudre

We approach the development of models and control strategies of susceptible-infected-susceptible (SIS) epidemic processes from the perspective of marked temporal point processes and stochastic optimal control of stochastic differential…

Optimization and Control · Mathematics 2018-12-04 Lars Lorch , Abir De , Samir Bhatt , William Trouleau , Utkarsh Upadhyay , Manuel Gomez-Rodriguez

For a recently derived pairwise model of network epidemics with non-Markovian recovery, we prove that under some mild technical conditions on the distribution of the infectious periods, smaller variance in the recovery time leads to higher…

Populations and Evolution · Quantitative Biology 2018-12-27 Zsolt Vizi , István Z. Kiss , Joel C. Miller , Gergely Röst

Advances in mathematical epidemiology have led to a better understanding of the risks posed by epidemic spreading and informed strategies to contain disease spread. However, a challenge that has been overlooked is that, as a disease becomes…

Physics and Society · Physics 2016-02-17 Lucas Böttcher , Olivia Woolley-Meza , Nuno A. M. Araújo , Hans J. Herrmann , Dirk Helbing

During an epidemic, individual nodes in a network may adapt their connections to reduce the chance of infection. A common form of adaption is avoidance rewiring, where a noninfected node breaks a connection to an infected neighbor and forms…

Adaptation and Self-Organizing Systems · Physics 2018-01-24 Jason Hindes , Ira B. Schwartz , Leah B. Shaw

In this paper, we study a novel control method for a generalized SIS epidemic process. In particular, we use predictive control to design optimal protective resource distribution strategies which balance the need to eliminate the epidemic…

Optimization and Control · Mathematics 2018-08-17 Nicholas J. Watkins , George J. Pappas

This paper investigates the optimal harvesting strategy for a single species living in random environments whose growth is given by a regime-switching diffusion. Harvesting acts as a (stochastic) control on the size of the population. The…

Optimization and Control · Mathematics 2016-08-02 Qingshuo Song , Richard Stockbridge , Chao Zhu

The Poisson distribution is the probability distribution of the number of independent events in a given period of time. Although the Poisson distribution appears ubiquitously in various stochastic dynamics of gene expression, both as…

Statistical Mechanics · Physics 2024-10-02 Julian Lee

We introduce two stochastic chemostat models consisting in a coupled population-nutrient process reflecting the interaction between the nutrient and the bacterias in the chemostat with finite volume. The nutrient concentration evolves…

Probability · Mathematics 2012-06-19 Pierre Collet , Servet Martinez , Sylvie Meleard , Jaime San Martin

Understanding the conditions ensuring the persistence of a population is an issue of primary importance in population biology. The first theoretical approach to the problem dates back to the 50's with the KiSS (after Kierstead, Slobodkin…

Populations and Evolution · Quantitative Biology 2015-09-07 Stefano Berti , Massimo Cencini , Davide Vergni , Angelo Vulpiani

Social distancing reduces infectious disease transmission by limiting contact frequency and proximity within a community. However, compliance varies due to its impact on daily life. This paper explores the effects of compliance on social…

Optimization and Control · Mathematics 2024-08-27 Hyelim Shin , Taesik Lee

The abundance of a species' population in an ecosystem is rarely stationary, often exhibiting large fluctuations over time. Using historical data on marine species, we show that the year-to-year fluctuations of population growth rate obey a…

Adaptation and Self-Organizing Systems · Physics 2015-06-02 Jie Sun , Sean P. Cornelius , John Janssen , Kimberly A. Gray , Adilson E. Motter

The question of whether biological populations survive or are eventually driven to extinction has long been examined using mathematical models. In this work we study population survival or extinction using a stochastic, discrete…

Populations and Evolution · Quantitative Biology 2021-09-15 Yifei Li , Stuart T. Johnston , Pascal R. Buenzli , Peter van Heijster , Matthew J. Simpson

Frequency-dependent selection reflects the interaction between different species as they battle for limited resources in their environment. In a stochastic evolutionary game the species relative fitnesses guides the evolutionary dynamics…

Probability · Mathematics 2020-12-29 Lea Popovic , Liam Peuckert

There has been much recent interest in screening populations for an infectious disease. Here, we present a stochastic-control model, wherein the optimum screening policy is provably difficult to find, but wherein Thompson sampling has…

Physics and Society · Physics 2020-11-03 Jakub Marecek