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We present a method to obtain numerically accurate values of configurational free energies of semiflexible macromolecular systems, based on the technique of thermodynamic integration combined with normal-mode analysis of a reference system…

Biomolecules · Quantitative Biology 2018-10-17 Stefan M. Giovan , Robert G. Scharein , Andreas Hanke , Stephen D. Levene

This paper is motivated by the problem of error control in network coding when errors are introduced in a random fashion (rather than chosen by an adversary). An additive-multiplicative matrix channel is considered as a model for random…

Information Theory · Computer Science 2019-05-07 Danilo Silva , Frank R. Kschischang , Ralf Kötter

We calculate the expectation value of an arbitrary product of characteristic polynomials of complex random matrices and their hermitian conjugates. Using the technique of orthogonal polynomials in the complex plane our result can be written…

High Energy Physics - Theory · Physics 2010-04-05 G. Akemann , G. Vernizzi

The formation of secondary structures by a random RNA sequence is studied as a model system for the sequence-structure problem omnipresent in biopolymers. Several toy energy models are introduced to allow detailed analytical and numerical…

Statistical Mechanics · Physics 2009-11-07 R. Bundschuh , T. Hwa

RNA secondary structures of increasing complexity are probed combining single molecule stretching experiments and stochastic unfolding/refolding simulations. We find that force-induced unfolding pathways cannot usually be interpretated by…

Biological Physics · Physics 2015-06-26 S. Harlepp , T. Marchal , J. Robert , J-F. Leger , A. Xayaphoummine , H. Isambert , D. Chatenay

The network density matrix formalism allows for describing the dynamics of information on top of complex structures and it has been successfully used to analyze from system's robustness to perturbations to coarse graining multilayer…

Physics and Society · Physics 2023-05-03 Arsham Ghavasieh , Manlio De Domenico

The main objects under consideration in this thesis are called maps, a certain class of graphs embedded on surfaces. Our problems have a powerful relatively recent tool in common, the so-called topological recursion (TR) introduced by…

Mathematical Physics · Physics 2020-02-04 Elba Garcia-Failde

We investigate the topologies of random geometric complexes built over random points sampled on Riemannian manifolds in the so-called "thermodynamic" regime. We prove the existence of universal limit laws for the topologies; namely, the…

Probability · Mathematics 2020-11-23 Antonio Auffinger , Antonio Lerario , Erik Lundberg

We consider a certain abstract of RNA secondary structures, which is closely related to RNA shapes. The generating function counting the number of the abstract structures is obtained by means of Narayana numbers and 2-Motzkin paths, through…

Combinatorics · Mathematics 2019-07-18 Sang Kwan Choi

In this article the configurational space of two simple protein models consisting of polymers composed of a periodic sequence of four different kinds of monomers is studied as a function of temperature. In the protein models, hydrogen bond…

Soft Condensed Matter · Physics 2012-03-26 Hanif Bayat Movahed , Ramses van Zon , Jeremy Schofield

Complex numbers define the relationship between entities in many situations. A canonical example would be the off-diagonal terms in a Hamiltonian matrix in quantum physics. Recent years have seen an increasing interest to extend the tools…

Social and Information Networks · Computer Science 2023-07-06 Yu Tian , Renaud Lambiotte

Complex prediction models such as deep learning are the output from fitting machine learning, neural networks, or AI models to a set of training data. These are now standard tools in science. A key challenge with the current generation of…

Machine Learning · Computer Science 2022-10-21 Meng Liu , Tamal K. Dey , David F. Gleich

Random matrix theory allows for the deduction of stability criteria for complex systems using only a summary knowledge of the statistics of the interactions between components. As such, results like the well-known elliptical law are…

Disordered Systems and Neural Networks · Physics 2023-11-06 Lyle Poley , Tobias Galla , Joseph W. Baron

The problem of RNA secondary structure design (also called inverse folding) is the following: given a target secondary structure, one aims to create a sequence that folds into, or is compatible with, a given structure. In several practical…

Quantitative Methods · Quantitative Biology 2013-08-02 Yu Zhou , Yann Ponty , Stéphane Vialette , Jérôme Waldispühl , Yi Zhang , Alain Denise

The thesis consists of two projects. In the first project, we present a software that analyses RNA secondary structures and compares them. The goal of this software is to find the differences between two secondary structures (experimental…

Biomolecules · Quantitative Biology 2012-12-18 Asaf Farhi

We review our recent results on pseudo-hermitian random matrix theory which were hitherto presented in various conferences and talks. (Detailed accounts of our work will appear soon in separate publications.) Following an introduction of…

Mathematical Physics · Physics 2021-10-27 Joshua Feinberg , Roman Riser

We study a new class of matrix models, formulated on a lattice. On each site are $N$ states with random energies governed by a Gaussian random matrix Hamiltonian. The states on different sites are coupled randomly. We calculate the density…

Condensed Matter · Physics 2009-10-22 E. Brézin , A. Zee

We introduce a natural class of models of random chain complexes of real vector spaces that some classical ensembles of random matrices, the length $1$ case. We are interested here in the homological properties of these random complexes.…

Probability · Mathematics 2026-02-12 Ayat Ababneh , Matthew Kahle

We show that the large N expansion in the multi-trace 1 formal hermitian matrix model is governed by the topological recursion of [Eynard and Orantin, 2007] with initial conditions. In terms of a 1d gas of eigenvalues, this model includes -…

Mathematical Physics · Physics 2016-10-05 Gaëtan Borot

An elementary, at the undergraduate level derivation is given of precise upper bounds of the number of various RNA secondary structures. The method works when the generating function has multiple singularities at the circle of convergence,…

Complex Variables · Mathematics 2014-07-29 Alexander I. Kheyfits