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In this work we obtain the planar free energy for the Hermitian one-matrix model with various choices of the potential. We accomplish this by applying an approach that bypasses the usual diagonalization of the matrices and the introduction…

High Energy Physics - Theory · Physics 2022-03-02 Bartomeu Fiol , Alan Rios Fukelman

We present a diagrammatic technique for calculating the free energy of the Hermitian one-matrix model to all orders of 1/N expansion in the case where the limiting eigenvalue distribution spans arbitrary (but fixed) number of disjoint…

High Energy Physics - Theory · Physics 2010-02-03 L. Chekhov , B. Eynard

The topological interaction arising in interlinked polymeric rings such as DNA catenanes is considered. More specifically, the free energy for a pair of linked random walk rings is derived where the distance $R$ between two segments each of…

Statistical Mechanics · Physics 2016-08-31 Matthias Otto

In biology, predicting RNA secondary structures plays a vital role in determining its physical and chemical properties. Although we have powerful energy models to predict them as well as parametric analysis to understand the models…

Biomolecules · Quantitative Biology 2023-05-01 Doan Dai Nguyen

The study of gene regulation and expression is often discussed in quantitative terms. In particular, the expression of genes is regularly characterized with respect to how much, how fast, when and where. Whether discussing the level of gene…

Molecular Networks · Quantitative Biology 2007-05-23 Lacramioara Bintu , Nicolas E. Buchler , Hernan G. Garcia , Ulrich Gerland , Terence Hwa , Jane' Kondev , Rob Phillips

This contribution focuses on the fascinating RNA molecule, its sequence-dependent folding driven by base-pairing interactions, the interplay between these interactions and natural evolution, and its multiple regulatory roles. The four of us…

Statistical Mechanics · Physics 2022-07-28 Simona Cocco , Andrea De Martino , Andrea Pagnani , Martin Weigt

Motivation: RNA design aims to find RNA sequences that fold into a given target secondary structure, a problem also known as RNA inverse folding. However, not all target structures are designable. Recent advances in RNA designability have…

Data Structures and Algorithms · Computer Science 2026-04-28 Tianshuo Zhou , David H. Mathews , Liang Huang

We extend the relation between random matrices and free probability theory from the level of expectations to the level of all correlation functions (which are classical cumulants of traces of products of the matrices). We introduce the…

Operator Algebras · Mathematics 2007-06-13 Benoit Collins , James A. Mingo , Piotr Sniady , Roland Speicher

We review a collection of models of random simplicial complexes together with some of the most exciting phenomena related to them. We do not attempt to cover all existing models, but try to focus on those for which many important results…

Probability · Mathematics 2022-05-04 Omer Bobrowski , Dmitri Krioukov

Random Hermitian matrices are used to model complex systems without time-reversal invariance. Adding an external source to the model can have the effect of shifting some of the matrix eigenvalues, which corresponds to shifting some of the…

Mathematical Physics · Physics 2015-05-20 Marco Bertola , Robert Buckingham , Seung-Yeop Lee , Virgil U. Pierce

Single-cell RNA sequencing (scRNA-seq) is a relatively new technology that has stimulated enormous interest in statistics, data science, and computational biology due to the high dimensionality, complexity, and large scale associated with…

Machine Learning · Statistics 2023-10-25 Yuta Hozumi , Guo-Wei Wei

Using force as a probe to map the folding landscapes of RNA molecules has become a reality thanks to major advances in single molecule pulling experiments. Although the unfolding pathways under tension are complicated to predict studies in…

Biological Physics · Physics 2018-03-14 Changbong Hyeon , D. Thirumalai

We introduce a new class of large structured random matrices characterized by four fundamental properties which we discuss. We prove that this class is stable under matrix-valued and pointwise non-linear operations. We then formulate an…

Probability · Mathematics 2025-06-09 Denis Bernard , Ludwig Hruza

One of the most important applications of topological recursion concerns spectral curves for which the functions $(x,y)$ defining the spectral curve are allowed to have logarithmic singularities. This occurs for instance for Seiberg-Witten…

Mathematical Physics · Physics 2026-04-29 Alexander Hock , Olivier Marchal , Nicolas Orantin

We construct ensembles of random integrable matrices with any prescribed number of nontrivial integrals and formulate integrable matrix theory (IMT) -- a counterpart of random matrix theory (RMT) for quantum integrable models. A type-M…

Mesoscale and Nanoscale Physics · Physics 2016-05-20 Emil A. Yuzbashyan , B. Sriram Shastry , Jasen A. Scaramazza

We consider the additive superimposition of an extensive number of independent Euclidean Random Matrices in the high-density regime. The resolvent is computed with techniques from free probability theory, as well as with the replica method…

Disordered Systems and Neural Networks · Physics 2020-05-27 Aldo Battista , Remi Monasson

We focus on functional renormalization for ensembles of several (say $n\geq 1$) random matrices, whose potentials include multi-traces, to wit, the probability measure contains factors of the form $ \exp[-\mathrm{Tr}(V_1)\times\ldots\times…

Mathematical Physics · Physics 2022-06-16 Carlos I. Perez-Sanchez

We consider Gaussian fields of real symmetric, complex Hermitian or quaternionic Hermitian matrices over an electrical network, and describe how the isomorphisms between these fields and random walks give rise to topological expansions…

Probability · Mathematics 2022-08-31 Titus Lupu

We extend recent methods for parametric sequence alignment to the parameter space for scoring RNA folds. This involves the construction of an RNA polytope. A vertex of this polytope corresponds to RNA secondary structures with common…

Biomolecules · Quantitative Biology 2009-04-24 Valerie Hower , Christine E. Heitsch

We consider higher-rank versions of the standard numerical range for matrices. A central motivation for this investigation comes from quantum error correction. We develop the basic structure theory for the higher-rank numerical ranges, and…

Functional Analysis · Mathematics 2007-05-23 Man-Duen Choi , David W. Kribs , Karol Zyczkowski