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The role of the Uncertainty Principle is examined through the examples of squeezing, information capacity, and position monitoring. It is suggested that more attention should be directed to conceptual considerations in quantum information…

Quantum Physics · Physics 2007-05-23 Horace P. Yuen

Image-based simulation, the use of 3D images to calculate physical quantities, fundamentally relies on image segmentation to create the computational geometry. However, this process introduces image segmentation uncertainty because there is…

Computational Engineering, Finance, and Science · Computer Science 2021-09-20 Michael C. Krygier , Tyler LaBonte , Carianne Martinez , Chance Norris , Krish Sharma , Lincoln N. Collins , Partha P. Mukherjee , Scott A. Roberts

We prove a quantitative uncertainty principle at low energies for the Laplacian on fairly general weighted graphs with a uniform explicit control of the constants in terms of geometric quantities. A major step consists in establishing lower…

Functional Analysis · Mathematics 2018-04-02 Daniel Lenz , Peter Stollmann , Gunter Stolz

Uncertainty quantification complements model predictions by characterizing their reliability, which is essential for high-stakes decision making such as medical image segmentation. However, most existing methods reduce uncertainty to a…

Computer Vision and Pattern Recognition · Computer Science 2026-05-13 An Sui , Yuzhu Li , Gunter Schumann , Fuping Wu , Xiahai Zhuang

In the analysis of the on-axis intensity for a highly focused optical field it is highly desirable to deal with effective relations aimed at characterizing the field behavior in a rather simple fashion. Here, a novel and adequate measure…

Optics · Physics 2020-09-23 R. Martinez-Herrero , A. Carnicer , I. Juvells , A. S. Sanz

There are strong incentives to build models that demonstrate outstanding predictive performance on various datasets and benchmarks. We believe these incentives risk a narrow focus on models and on the performance metrics used to evaluate…

Machine Learning · Computer Science 2022-06-07 David Lovell , Dimity Miller , Jaiden Capra , Andrew Bradley

Single-cell reference atlases are large-scale, cell-level maps that capture cellular heterogeneity within an organ using single cell genomics. Given their size and cellular diversity, these atlases serve as high-quality training data for…

Genomics · Quantitative Biology 2022-11-09 Jan Engelmann , Leon Hetzel , Giovanni Palla , Lisa Sikkema , Malte Luecken , Fabian Theis

Advances in architectural design, data availability, and compute have driven remarkable progress in semantic segmentation. Yet, these models often rely on relaxed Bayesian assumptions, omitting critical uncertainty information needed for…

Computer Vision and Pattern Recognition · Computer Science 2026-02-19 M. M. A. Valiuddin , R. J. G. van Sloun , C. G. A. Viviers , P. H. N. de With , F. van der Sommen

We study uncertainty relations for pairs of conjugate variables like number and angle, of which one takes integer values and the other takes values on the unit circle. The translation symmetry of the problem in either variable implies that…

Quantum Physics · Physics 2018-04-03 Paul Busch , Jukka Kiukas , Reinhard F. Werner

The visual information in V1 is processed by an array of modules called orientation preference columns. In some species including humans, orientation columns are radially arranged around singular points like the spokes of a wheel, that are…

Mathematical Physics · Physics 2010-07-09 Davide Barbieri , Giovanna Citti , Gonzalo Sanguinetti , Alessandro Sarti

Classifiers are often tested on relatively small data sets, which should lead to uncertain performance metrics. Nevertheless, these metrics are usually taken at face value. We present an approach to quantify the uncertainty of…

Machine Learning · Statistics 2021-03-05 Niklas Tötsch , Daniel Hoffmann

We demonstrate that final-state uncertainty is ubiquitous in multistable systems of coupled neuronal maps, meaning that predicting whether one such system will eventually be chaotic or nonchaotic is often nearly impossible. We propose a…

Neurons and Cognition · Quantitative Biology 2025-07-22 Brandon B. Le , Bennett Lamb , Luke Benfer , Sriharsha Sambangi , Nisal Geemal Vismith , Akshaj Jagarapu

Uncertainty quantification for inverse problems in imaging has drawn much attention lately. Existing approaches towards this task define uncertainty regions based on probable values per pixel, while ignoring spatial correlations within the…

Computer Vision and Pattern Recognition · Computer Science 2024-01-23 Omer Belhasin , Yaniv Romano , Daniel Freedman , Ehud Rivlin , Michael Elad

Cell tracking and segmentation assist biologists in extracting insights from large-scale microscopy time-lapse data. Driven by local accuracy metrics, current tracking approaches often suffer from a lack of long-term consistency and the…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Timo Kaiser , Maximilian Schier , Bodo Rosenhahn

In a data-scarce field such as healthcare, where models often deliver predictions on patients with rare conditions, the ability to measure the uncertainty of a model's prediction could potentially lead to improved effectiveness of decision…

Machine Learning · Statistics 2020-05-26 Lotta Meijerink , Giovanni Cinà , Michele Tonutti

In many areas of engineering and sciences, decision rules and control strategies are usually designed based on nominal values of relevant system parameters. To ensure that a control strategy or decision rule will work properly when the…

Probability · Mathematics 2020-06-16 Xinjia Chen

Due to lack of scientific understanding, some mechanisms may be missing in mathematical modeling of complex phenomena in science and engineering. These mathematical models thus contain some uncertainties such as uncertain parameters. One…

Probability · Mathematics 2012-04-05 Jinqiao Duan , Ting Gao , Guowei He

Segmentation tasks in medical imaging are inherently ambiguous: the boundary of a target structure is oftentimes unclear due to image quality and biological factors. As such, predicted segmentations from deep learning algorithms are…

Image and Video Processing · Electrical Eng. & Systems 2019-11-18 Katharina Hoebel , Ken Chang , Jay Patel , Praveer Singh , Jayashree Kalpathy-Cramer

Accurate medical image segmentation is crucial for diagnosis and analysis. However, the models without calibrated uncertainty estimates might lead to errors in downstream analysis and exhibit low levels of robustness. Estimating the…

Image and Video Processing · Electrical Eng. & Systems 2021-09-16 Yanwu Yang , Xutao Guo , Yiwei Pan , Pengcheng Shi , Haiyan Lv , Ting Ma

Although cell shape can reflect the mechanical and biochemical properties of the cell and its environment, quantification of 3D cell shapes within 3D tissues remains difficult, typically requiring digital reconstruction from a stack of 2D…

Quantitative Methods · Quantitative Biology 2019-03-06 Tristan A. Sharp , Matthias Merkel , M. Lisa Manning , Andrea J. Liu
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