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We consider high-dimensional regression over subgroups of observations. Our work is motivated by biomedical problems, where disease subtypes, for example, may differ with respect to underlying regression models, but sample sizes at the…

This article introduces a novel approach to the classification of categorical time series under the supervised learning paradigm. To construct meaningful features for categorical time series classification, we consider two relevant…

Methodology · Statistics 2021-02-05 Zeda Li , Scott A. Bruce , Tian Cai

Spectrograms visualize the frequency components of a given signal which may be an audio signal or even a time-series signal. Audio signals have higher sampling rate and high variability of frequency with time. Spectrograms can capture such…

Signal Processing · Electrical Eng. & Systems 2021-09-06 Sidharth Srivatsav Sribhashyam , Md Sirajus Salekin , Dmitry Goldgof , Ghada Zamzmi , Mark Last , Yu Sun

Modeling the time-series of high-dimensional, longitudinal data is important for predicting patient disease progression. However, existing neural network based approaches that learn representations of patient state, while very flexible, are…

Machine Learning · Computer Science 2021-06-21 Zeshan Hussain , Rahul G. Krishnan , David Sontag

Biological cells, by definition, are the basic units which contain the fundamental molecules of life of which all living things are composed. Understanding how they function and differentiating cells from one another therefore is of…

Signal Processing · Electrical Eng. & Systems 2021-01-07 Hassan Raji , Muhammad Tayyab , Jianye Sui , Seyed Reza Mahmoodi , Mehdi Javanmard

We consider the problem of sequentially testing for changes in the mean parameter of a time series, compared to a benchmark period. Most tests in the literature focus on the null hypothesis of a constant mean versus the alternative of a…

Methodology · Statistics 2025-09-23 Patrick Bastian , Tim Kutta , Rupsa Basu , Holger Dette

Quantification of system-wide perturbations from time series -omic data (i.e. a large number of variables with multiple measures in time) provides the basis for many downstream hypothesis generating tools. Here we propose a method,…

Quantitative Methods · Quantitative Biology 2016-12-30 Yi H. Yan , Elizabeth D. Trippe , Juan B. Gutierrez

Time series similarity measures are highly relevant in a wide range of emerging applications including training machine learning models, classification, and predictive modeling. Standard similarity measures for time series most often…

Machine Learning · Computer Science 2021-01-22 Lucas Cassiel Jacaruso

The Cox model is an indispensable tool for time-to-event analysis, particularly in biomedical research. However, medicine is undergoing a profound transformation, generating data at an unprecedented scale, which opens new frontiers to study…

Methodology · Statistics 2023-03-07 Alexander W. Jung , Moritz Gerstung

Time series data, defined by equally spaced points over time, is essential in fields like medicine, telecommunications, and energy. Analyzing it involves tasks such as classification, clustering, prototyping, and regression. Classification…

Machine Learning · Computer Science 2025-02-27 Ali Ismail-Fawaz

Several experimental studies claim to be able to predict the outcome of simple decisions from brain signals measured before subjects are aware of their decision. Often, these studies use multivariate pattern recognition methods with the…

Neurons and Cognition · Quantitative Biology 2016-06-21 Marco Rusconi , Angelo Valleriani

Identifying reliable biomarkers for predicting clinical events in longitudinal studies is important for accurate disease prognosis and for guiding development of new treatments. However, prognostic studies are often observational, making it…

Methodology · Statistics 2025-08-12 Ainesh Sewak , Vanda Inacio , Joanne Wuu , Michael Benatar , Torsten Hothorn

Complex data features, such as unmodelled censored event times and variables with time-dependent effects, are common in cancer recurrence studies and pose challenges for Bayesian survival modelling. Current methodologies for predictive…

Methodology · Statistics 2026-01-12 Saku Suorsa , Aki Vehtari

CMOS-based sensor array chips provide new and attractive features as compared to today's standard tools for medical, diagnostic, and biotechnical applications. Examples for molecule- and cell-based approaches and related circuit design…

Many planning and decision activities in logistics and supply chain management are based on forecasts of multiple time dependent factors. Therefore, the quality of planning depends on the quality of the forecasts. We compare various…

Machine Learning · Statistics 2024-06-07 Lena Schmid , Moritz Roidl , Markus Pauly

In this paper, we consider a new low-quality label learning problem: learning time series detection models from temporally imprecise labels. In this problem, the data consist of a set of input time series, and supervision is provided by a…

Machine Learning · Statistics 2017-04-14 Roy J. Adams , Benjamin M. Marlin

An important paradigm in smart health is developing diagnosis tools and monitoring a patient's heart activity through processing Electrocardiogram (ECG) signals is a key example, sue to high mortality rate of heart-related disease. However,…

Signal Processing · Electrical Eng. & Systems 2018-11-02 Jiaming Chen , Ali Valehi , Abolfazl Razi

Spectral estimation (SE) aims to identify how the energy of a signal (e.g., a time series) is distributed across different frequencies. This can become particularly challenging when only partial and noisy observations of the signal are…

Machine Learning · Statistics 2019-01-15 Felipe Tobar

A consolidating method for analyzing series of observations based on a fitted model of a mixture of catalysts of the main components is proposed, which makes it possible to study any number of markers. Contrasting the longitudinal approach,…

Methodology · Statistics 2023-04-12 Anastasia Grigoreva , Andrey Trufanov , Stanislav Grigorev

Cross-subject generalization in biomedical time-series refers to training on data from some subjects and testing on unseen subjects.The key challenge is to suppress subject specific variability in BTS representations.Most existing methods…

Machine Learning · Computer Science 2026-05-27 Guikang Du , Haoran Li , Xinyu Liu , Zhibo Zhang , Xiaoli Gong , Jin Zhang