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Machine learning models that utilize patient data across time (rather than just the most recent measurements) have increased performance for many risk stratification tasks in the intensive care unit. However, many of these models and their…

Machine Learning · Computer Science 2021-09-24 Nari Johnson , Sonali Parbhoo , Andrew Slavin Ross , Finale Doshi-Velez

Serology testing can identify past infection by quantifying the immune response of an infected individual providing important public health guidance. Individual immune responses are time-dependent, which is reflected in antibody…

Quantitative Methods · Quantitative Biology 2022-08-04 Prajakta Bedekar , Anthony J. Kearsley , Paul N. Patrone

Multivariate time series classification is a task with increasing importance due to the proliferation of new problems in various fields (economy, health, energy, transport, crops, etc.) where a large number of information sources are…

Machine Learning · Computer Science 2020-09-09 Francisco J. Baldán , José M. Benítez

This paper considers how to classify the effects of interventions in causal models for outcomes and exposures observed over time. First, we demonstrate the limitations of the most common uses of potential outcomes and causal directed…

Methodology · Statistics 2026-05-29 Russell Steele , Naftali Weinberger , Tess Baker , Ian Shrier

This work investigates whether time series of natural phenomena can be understood as being generated by sequences of latent states which are ordered in systematic and regular ways. We focus on clinical time series and ask whether clinical…

Machine Learning · Computer Science 2025-08-29 Michael Hagmann , Michael Staniek , Stefan Riezler

Despite the excelling performance of machine learning models, understanding their decisions remains a long-standing goal. Although commonly used attribution methods from explainable AI attempt to address this issue, they typically rely on…

Machine Learning · Computer Science 2025-11-20 Juan Miguel Lopez Alcaraz , Nils Strodthoff

Multiple sclerosis is a disease that affects the brain and spinal cord, it can lead to severe disability and has no known cure. The majority of prior work in machine learning for multiple sclerosis has been centered around using Magnetic…

Machine Learning · Computer Science 2023-09-12 Alexander Norcliffe , Lev Proleev , Diana Mincu , Fletcher Lee Hartsell , Katherine Heller , Subhrajit Roy

Continuous collection of physiological data from wearable sensors enables temporal characterization of individual behaviors. Understanding the relation between an individual's behavioral patterns and psychological states can help identify…

This paper presents an approach to modeling progressive event-history data when the overall objective is prediction based on time-dependent covariates. This approach does not model the hazard function directly. Instead, it models the…

Methodology · Statistics 2010-09-07 Song Cai , James V. Zidek , Nathaniel Newlands

Electrocardiogram~(ECG), a key bioelectrical time-series signal, is crucial for assessing cardiac health and diagnosing various diseases. Given its time-series format, ECG data is often incorporated into pre-training datasets for…

Signal Processing · Electrical Eng. & Systems 2026-02-26 Zhijiang Tang , Jiaxin Qi , Yuhua Zheng , Jianqiang Huang

The use of observational time series data to assess the impact of multi-time point interventions is becoming increasingly common as more health and activity data are collected and digitized via wearables, social media, and electronic health…

Methodology · Statistics 2020-12-01 Roy Adams , Suchi Saria , Michael Rosenblum

Auditory and visual signals usually present together and correlate with each other, not only in natural environments but also in clinical settings. However, the audio-visual modelling in the latter case can be more challenging, due to the…

Computer Vision and Pattern Recognition · Computer Science 2023-10-26 Jianbo Jiao , Mohammad Alsharid , Lior Drukker , Aris T. Papageorghiou , Andrew Zisserman , J. Alison Noble

Many medical decisions involve the use of dynamic information collected on individual patients toward predicting likely transitions in their future health status. If accurate predictions are developed, then a prognostic mode can identify…

Methodology · Statistics 2018-02-22 Aasthaa Bansal , Patrick J. Heagerty

Machine learning for data-driven diagnosis has been actively studied in medicine to provide better healthcare. Supporting analysis of a patient cohort similar to a patient under treatment is a key task for clinicians to make decisions with…

Medical Physics · Physics 2020-03-25 Rongchen Guo , Takanori Fujiwara , Yiran Li , Kelly M. Lima , Soman Sen , Nam K. Tran , Kwan-Liu Ma

In biomedical applications, the similarity between a signal measured from an injured subject and a reference signal measured from a normal subject can be used to quantify the injury severity. This paper proposes a generalization of the…

Applications · Statistics 2016-10-24 A. Olenko , K. T. Wong , H. Mir , H. Al-Nashash

Auxiliary data sources have become increasingly important in epidemiological surveillance, as they are often available at a finer spatial and temporal resolution, larger coverage, and lower latency than traditional surveillance signals. We…

Machine Learning · Computer Science 2023-09-29 Aaron Rumack , Roni Rosenfeld , F. William Townes

In this paper, we develop a novel logic-based approach to detecting high-level temporally extended events from timestamped data and background knowledge. Our framework employs logical rules to capture existence and termination conditions…

Artificial Intelligence · Computer Science 2026-04-24 Yvon K. Awuklu , Meghyn Bienvenu , Katsumi Inoue , Vianney Jouhet , Fleur Mougin

A coupled map is suggested to investigate various spatial or temporal designs in biology: Several cells (or tissues) in an organ are considered as connected to each other in terms of some molecular diffusions or electrical potential…

General Physics · Physics 2011-06-07 Caglar Tuncay

This article studies the estimation of the causal effect of a time-varying treatment on time-to-an-event or on some other continuously distributed outcome. The paper applies to the situation where treatment is repeatedly adapted to…

Statistics Theory · Mathematics 2008-06-19 Judith J. Lok

Multi-modal biomedical time series (MBTS) data offers a holistic view of the physiological state, holding significant importance in various bio-medical applications. Owing to inherent noise and distribution gaps across different modalities,…

Machine Learning · Computer Science 2023-12-08 Hongbo Guo , Xinzi Xu , Hao Wu , Guoxing Wang
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