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Currently, third-generation sequencing techniques, which allow to obtain much longer DNA reads compared to the next-generation sequencing technologies, are becoming more and more popular. There are many possibilities to combine data from…

Genomics · Quantitative Biology 2019-05-23 Wiktor Kuśmirek , Wiktor Franus , Robert Nowak

Speculative decoding (SD) has attracted a significant amount of research attention due to the substantial speedup it can achieve for LLM inference. However, despite the high speedups they offer, speculative decoding methods often achieve…

Computation and Language · Computer Science 2024-06-04 Wei Zhong , Manasa Bharadwaj

Peptide drugs incorporating non-standard amino acids (NSAAs) offer improved binding affinity and improved pharmacological properties. However, existing peptide design methods are limited to standard amino acids, leaving NSAA-aware design…

Biomolecules · Quantitative Biology 2025-10-07 Tao Guo , Junbo Yin , Yu Wang , Xin Gao

Third-generation nanopore sequencers offer a feature called selective sequencing or 'Read Until' that allows genomic reads to be analyzed in real-time and abandoned halfway, if not belonging to a genomic region of 'interest'. This selective…

Hardware Architecture · Computer Science 2022-11-15 Po Jui Shih , Hassaan Saadat , Sri Parameswaran , Hasindu Gamaarachchi

Fast 4$\pi$ solid angle particle track recognition has been a challenge in particle physics for a long time, especially in using nuclear emulsion detectors. The recent advances in computing technology opened the way for its realization. A…

Instrumentation and Detectors · Physics 2015-06-18 A. Ariga , T. Ariga

The rapid rise of large-scale foundation models has reshaped the landscape of image segmentation, with models such as Segment Anything achieving unprecedented versatility across diverse vision tasks. However, previous generations-including…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Tianrun Chen , Runlong Cao , Xinda Yu , Lanyun Zhu , Chaotao Ding , Deyi Ji , Cheng Chen , Qi Zhu , Chunyan Xu , Papa Mao , Ying Zang

Dedicated accelerator hardware has become essential for processing AI-based workloads, leading to the rise of novel accelerator architectures. Furthermore, fundamental differences in memory architecture and parallelism have made these…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-04-19 Luk Burchard , Max Xiaohang Zhao , Johannes Langguth , Aydın Buluç , Giulia Guidi

Accurate detection of pulmonary nodules with high sensitivity and specificity is essential for automatic lung cancer diagnosis from CT scans. Although many deep learning-based algorithms make great progress for improving the accuracy of…

Image and Video Processing · Electrical Eng. & Systems 2019-07-30 Jingya Liu , Liangliang Cao , Oguz Akin , Yingli Tian

3D Gaussian Splatting (3DGS) based Simultaneous Localization and Mapping (SLAM) systems can largely benefit from 3DGS's state-of-the-art rendering efficiency and accuracy, but have not yet been adopted in resource-constrained edge devices…

Hardware Architecture · Computer Science 2025-10-10 Leshu Li , Jiayin Qin , Jie Peng , Zishen Wan , Huaizhi Qu , Ye Han , Pingqing Zheng , Hongsen Zhang , Yu Cao , Tianlong Chen , Yang Katie Zhao

There is an explosion of data, documents, and other content, and people require tools to analyze and interpret these, tools to turn the content into information and knowledge. Topic modeling have been developed to solve these problems.…

Computation and Language · Computer Science 2015-10-23 Aaron Q Li

Analysis of DNA samples is an important step in forensics, and the speed of analysis can impact investigations. Comparison of DNA sequences is based on the analysis of short tandem repeats (STRs), which are short DNA sequences of 2-5 base…

Performance · Computer Science 2018-03-07 Siddharth Samsi , Brian Helfer , Jeremy Kepner , Albert Reuther , Darrell O. Ricke

Normalization techniques are a boon for modern deep learning. They let weights converge more quickly with often better generalization performances. It has been argued that the normalization-induced scale invariance among the weights…

Machine Learning · Computer Science 2021-01-19 Byeongho Heo , Sanghyuk Chun , Seong Joon Oh , Dongyoon Han , Sangdoo Yun , Gyuwan Kim , Youngjung Uh , Jung-Woo Ha

LiDAR-based 3D detection has made great progress in recent years. However, the performance of 3D detectors is considerably limited when deployed in unseen environments, owing to the severe domain gap problem. Existing domain adaptive 3D…

Computer Vision and Pattern Recognition · Computer Science 2023-08-17 Ziyu Li , Jingming Guo , Tongtong Cao , Liu Bingbing , Wankou Yang

The computing industry is forced to find alternative design approaches and computing platforms to sustain increased power efficiency, while providing sufficient performance. Among the examined solutions, Approximate Computing, Hardware…

Hardware Architecture · Computer Science 2024-09-09 Vasileios Leon

Genomic sequence alignment is an important research topic in bioinformatics and continues to attract significant efforts. As genomic data grow exponentially, however, most of alignment methods face challenges due to their huge computational…

Computational Engineering, Finance, and Science · Computer Science 2018-06-07 Hanyu Jiang , Narayan Ganesan , Yu-Dong Yao

Genome sequence analysis has enabled significant advancements in medical and scientific areas such as personalized medicine, outbreak tracing, and the understanding of evolution. Unfortunately, it is currently bottlenecked by the…

Transformer-based models are becoming more and more intelligent and are revolutionizing a wide range of human tasks. To support their deployment, AI labs offer inference services that consume hundreds of GWh of energy annually and charge…

Systems and Control · Electrical Eng. & Systems 2025-08-29 Ching-Yi Lin , Sahil Shah

Graph Neural Networks (GNNs) have shown great superiority on non-Euclidean graph data, achieving ground-breaking performance on various graph-related tasks. As a practical solution to train GNN on large graphs with billions of nodes and…

Machine Learning · Computer Science 2024-09-24 Zeyu Zhu , Peisong Wang , Qinghao Hu , Gang Li , Xiaoyao Liang , Jian Cheng

3D Gaussian splatting (3DGS) has become a vital tool for learning a radiance field from multiple posed images. Although 3DGS shows great advantages over NeRF in terms of rendering quality and efficiency, it remains a research challenge to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Jiaqi Liu , Zhizhong Han

Performances on standard 3D point cloud benchmarks have plateaued, resulting in oversized models and complex network design to make a fractional improvement. We present an alternative to enhance existing deep neural networks without any…

Computer Vision and Pattern Recognition · Computer Science 2023-03-02 Renrui Zhang , Liuhui Wang , Ziyu Guo , Jianbo Shi
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