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I introduce a framework to distinguish two domains of physics - the manifest (i.e. the directly observable empirical records in terms of manifest configurations) and the non-manifest domain of physics (i.e. the things that the manifest…

Quantum Physics · Physics 2024-08-13 Johannes Fankhauser

Observability is a modelling property that describes the possibility of inferring the internal state of a system from observations of its output. A related property, structural identifiability, refers to the theoretical possibility of…

Quantitative Methods · Quantitative Biology 2018-12-12 Alejandro F. Villaverde

Effectively modeling phenomena present in highly nonlinear dynamical systems whilst also accurately quantifying uncertainty is a challenging task, which often requires problem-specific techniques. We present a novel, domain-agnostic…

Machine Learning · Statistics 2021-10-26 Thomas M. McDonald , Mauricio A. Álvarez

Anomaly detection in medical imaging is a challenging task in contexts where abnormalities are not annotated. This problem can be addressed through unsupervised anomaly detection (UAD) methods, which identify features that do not match with…

Image and Video Processing · Electrical Eng. & Systems 2023-09-07 Geoffroy Oudoumanessah , Carole Lartizien , Michel Dojat , Florence Forbes

Significant progress has been made in developing identification and estimation techniques for missing data problems where modeling assumptions can be described via a directed acyclic graph. The validity of results using such techniques rely…

Methodology · Statistics 2023-06-13 Razieh Nabi , Rohit Bhattacharya

Model visualizations provide information that outputs alone might miss. But can we trust that model visualizations reflect model behavior? For instance, can they diagnose abnormal behavior such as planted backdoors or overregularization? To…

Machine Learning · Computer Science 2023-05-31 Jean-Stanislas Denain , Jacob Steinhardt

Testing procedures for predictive regressions with lagged autoregressive variables imply a suboptimal inference in presence of small violations of ideal assumptions. We propose a novel testing framework resistant to such violations, which…

Statistical Finance · Quantitative Finance 2016-12-16 Lorenzo Camponovo , Olivier Scaillet , Fabio Trojani

Causal inference often hinges on strong assumptions - such as no unmeasured confounding or perfect compliance - that are rarely satisfied in practice. Partial identification offers a principled alternative: instead of relying on…

Machine Learning · Computer Science 2025-08-20 Tobias Maringgele

Conformal prediction provides prediction sets with finite-sample marginal coverage, but many applications require coverage guarantees that adapt to individual test points, a subpopulation, or a structural component of the data. Existing…

Methodology · Statistics 2026-05-27 Yinjie Min , Liuhua Peng , Changliang Zou

In order to detect unknown intrusions and runtime errors of computer programs, the cyber-security community has developed various detection techniques. Anomaly detection is an approach that is designed to profile the normal runtime behavior…

Cryptography and Security · Computer Science 2021-06-03 Byunggu Yu , Junwhan Kim

Anomaly detection methods can be very useful in identifying unusual or interesting patterns in data. A recently proposed conditional anomaly detection framework extends anomaly detection to the problem of identifying anomalous patterns on a…

Machine Learning · Computer Science 2026-05-04 Michal Valko , Milos Hauskrecht

Outlying observations are frequently encountered across a wide spectrum of scientific domains, posing notable challenges to the generalizability of statistical models and the reproducibility of downstream analysis. They are identified…

Methodology · Statistics 2026-03-17 Dongliang Zhang , Masoud Asgharian , Martin A. Lindquist

The mathematical models used to represent physical phenomena are generally known to be imperfect representations of reality. Model inadequacies arise for numerous reasons, such as incomplete knowledge of the phenomena or computational…

Computational Engineering, Finance, and Science · Computer Science 2017-02-28 Teresa Portone , Damon McDougall , Robert D. Moser

Timely detection of concerning events is an important problem in clinical practice. In this paper, we consider the problem of conditional anomaly detection that aims to identify data instances with an unusual response, such as the omission…

Machine Learning · Computer Science 2026-04-27 Michal Valko , Hamed Valizadegan , Branislav Kveton , Gregory F. Cooper , Milos Hauskrecht

The search for faint emission or absorption lines in astronomical spectra has received considerable attention in recent years, especially in the X-ray wavelength range. These features usually appear as a deficit or excess of counts in a…

High Energy Astrophysical Phenomena · Physics 2018-10-05 Massimiliano Bonamente

Machine learning (ML) systems are increasingly deployed in high-stakes domains where reliability is paramount. This thesis investigates how uncertainty estimation can enhance the safety and trustworthiness of ML, focusing on selective…

Machine Learning · Computer Science 2025-09-09 Stephan Rabanser

This work addresses the challenge of providing consistent explanations for predictive models in the presence of model indeterminacy, which arises due to the existence of multiple (nearly) equally well-performing models for a given dataset…

Machine Learning · Computer Science 2023-06-14 Dan Ley , Leonard Tang , Matthew Nazari , Hongjin Lin , Suraj Srinivas , Himabindu Lakkaraju

This paper clarifies a fundamental difference between causal inference and traditional statistical inference by formalizing a mathematical distinction between their respective parameters. We connect two major approaches to causal inference,…

Methodology · Statistics 2025-08-29 Muye Liu , Jun Xie

Incipient anomalies present milder symptoms compared to severe ones, and are more difficult to detect and diagnose due to their close resemblance to normal operating conditions. The lack of incipient anomaly examples in the training data…

Machine Learning · Computer Science 2020-08-21 Yingshui Tan , Baihong Jin , Qiushi Cui , Xiangyu Yue , Alberto Sangiovanni Vincentelli

Many real world models can be characterized as weak, meaning that there is significant uncertainty in both the data input and inferences. This lack of determinism makes it especially difficult for users of computer decision aids to…

Artificial Intelligence · Computer Science 2013-04-10 Holly B. Jimison
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